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PDB: 265 件
4NI6
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Repeat domain 1 of Clostridium perfringens CPE0147
分子名称: Putative surface anchored protein
著者Kwon, H, Squire, C.J, Young, P.G, Baker, E.N.
登録日2013-11-05
公開日2013-12-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Autocatalytically generated Thr-Gln ester bond cross-links stabilize the repetitive Ig-domain shaft of a bacterial cell surface adhesin.
Proc.Natl.Acad.Sci.USA, 111, 2014
4N8Q
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BU of 4n8q by Molmil
Alternative substrates of Mycobacterium tuberculosis anthranilate phosphoribosyl transferase
分子名称: 2-amino-4-fluorobenzoic acid, Anthranilate phosphoribosyltransferase
著者Castell, A, Cookson, T.V.M, Bulloch, E, Evans, G.L, Baker, E.N, Lott, J.S, Parker, E.J.
登録日2013-10-17
公開日2014-04-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis.
Biochem.J., 461, 2014
4NS3
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Crystal structure of the Delta-pyrroline-5-carboxylate dehydrogenase from Mycobacterium tuberculosis bound with NAD and cobalamin
分子名称: COBALAMIN, Delta-1-pyrroline-5-carboxylate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Lagautriere, T, Bashiri, G, Baker, E.N.
登録日2013-11-27
公開日2015-01-14
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Use of a "silver bullet" to resolve crystal lattice dislocation disorder: A cobalamin complex of Delta (1)-pyrroline-5-carboxylate dehydrogenase from Mycobacterium tuberculosis.
J.Struct.Biol., 189, 2015
4M0R
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Trianthranilate-like analogue bound to anthranilate phosphoribosyltransferase (AnPRT; TrpD).
分子名称: 2,6-bis[(2-carboxyphenyl)amino]benzoic acid, Anthranilate phosphoribosyltransferase, DIMETHYL SULFOXIDE, ...
著者Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2013-08-02
公開日2014-05-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Repurposing the Chemical Scaffold of the Anti-Arthritic Drug Lobenzarit to Target Tryptophan Biosynthesis in Mycobacterium tuberculosis.
Chembiochem, 15, 2014
3RPK
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BU of 3rpk by Molmil
Structure of the Full-Length Major Pilin RrgB from Streptococcus pneumoniae
分子名称: Backbone pilus subunit
著者Paterson, N.G, Baker, E.N.
登録日2011-04-26
公開日2011-06-15
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of the Full-Length Major Pilin from Streptococcus pneumoniae: Implications for Isopeptide Bond Formation in Gram-Positive Bacterial Pili
Plos One, 6, 2011
4N5V
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Alternative substrates of Mycobacterium tuberculosis anthranilate phosphoribosyl transferase
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 2-amino-4-fluorobenzoic acid, Anthranilate phosphoribosyltransferase, ...
著者Castell, A, Cookson, T.V.M, Parker, E.J, Baker, E.N, Lott, J.S.
登録日2013-10-10
公開日2014-04-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis.
Biochem.J., 461, 2014
4P0D
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BU of 4p0d by Molmil
The T6 backbone pilin of serotype M6 Streptococcus pyogenes has a modular three-domain structure decorated with variable loops and extensions
分子名称: CALCIUM ION, IODIDE ION, Trypsin-resistant surface T6 protein
著者Young, P.G, Moreland, N.J, Loh, J.M, Bell, A, Atatoa-Carr, P, Proft, T, Baker, E.N.
登録日2014-02-20
公開日2014-08-27
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Conservation, Variability, and Immunogenicity of the T6 Backbone Pilin of Serotype M6 Streptococcus pyogenes.
Infect.Immun., 82, 2014
4N31
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Structure and activity of Streptococcus pyogenes SipA: a signal peptidase homologue essential for pilus polymerisation
分子名称: PHOSPHATE ION, PHOSPHATIDYLETHANOLAMINE, SipA
著者Young, P.G, Proft, T, Baker, E.N.
登録日2013-10-06
公開日2014-08-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure and activity of Streptococcus pyogenes SipA: a signal peptidase-like protein essential for pilus polymerisation.
Plos One, 9, 2014
6UCD
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The crystal structure of Staphylococcus aureus super antigen-like protein SSL10
分子名称: Exotoxin
著者Patel, D, Young, P.G, Bunker, R.D, Baker, E.N, Fraser, J.D.
登録日2019-09-16
公開日2020-08-05
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献The crystal structure of Staphylococcus aureus super antigen-like protein SSL10
To Be Published
2BLG
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STRUCTURAL BASIS OF THE TANFORD TRANSITION OF BOVINE BETA-LACTOGLOBULIN FROM CRYSTAL STRUCTURES AT THREE PH VALUES; PH 8.2
分子名称: BETA-LACTOGLOBULIN
著者Qin, B.Y, Bewley, M.C, Creamer, L.K, Baker, H.M, Baker, E.N, Jameson, G.B.
登録日1998-08-29
公開日1999-01-27
最終更新日2021-07-28
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Structural basis of the Tanford transition of bovine beta-lactoglobulin.
Biochemistry, 37, 1998
6BWG
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Crystal structure of native Rv2983 from Mycobacterium tuberculosis
分子名称: 2-phospho-L-lactate guanylyltransferase
著者Bashiri, G, Jirgis, E.N.M, Baker, E.N.
登録日2017-12-15
公開日2018-12-19
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献A revised biosynthetic pathway for the cofactor F420in prokaryotes.
Nat Commun, 10, 2019
6BWH
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Crystal structure of Mycoibacterium tuberculosis Rv2983 in complex with PEP
分子名称: 2-phospho-L-lactate guanylyltransferase, MAGNESIUM ION, PHOSPHOENOLPYRUVATE
著者Bashiri, G, Jirgis, E.N.M, Baker, E.N.
登録日2017-12-15
公開日2018-12-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献A revised biosynthetic pathway for the cofactor F420in prokaryotes.
Nat Commun, 10, 2019
2B7O
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The Structure of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase from Mycobacterium tuberculosis
分子名称: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG, MANGANESE (II) ION, O-DODECANYL OCTAETHYLENE GLYCOL, ...
著者Webby, C.J, Baker, H.M, Lott, J.S, Baker, E.N, Parker, E.J, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2005-10-05
公開日2005-10-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The structure of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis reveals a common catalytic scaffold and ancestry for type I and type II enzymes
J.Mol.Biol., 354, 2005
1LFH
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MOLECULAR REPLACEMENT SOLUTION OF THE STRUCTURE OF APOLACTOFERRIN, A PROTEIN DISPLAYING LARGE-SCALE CONFORMATIONAL CHANGE
分子名称: CHLORIDE ION, LACTOFERRIN
著者Anderson, B.F, Baker, E.N, Norris, G.E.
登録日1991-09-04
公開日1993-10-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Molecular replacement solution of the structure of apolactoferrin, a protein displaying large-scale conformational change.
Acta Crystallogr.,Sect.B, 47, 1991
2FYF
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BU of 2fyf by Molmil
Structure of a putative phosphoserine aminotransferase from Mycobacterium Tuberculosis
分子名称: GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION, ...
著者Coulibaly, F, Lassalle, E, Baker, E.N, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2006-02-07
公開日2007-01-16
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure of phosphoserine aminotransferase from Mycobacterium tuberculosis.
Acta Crystallogr.,Sect.D, 68, 2012
2F00
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Escherichia coli MurC
分子名称: MAGNESIUM ION, UDP-N-acetylmuramate--L-alanine ligase
著者Deva, T, Baker, E.N, Squire, C.J, Smith, C.A.
登録日2005-11-10
公開日2006-10-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of Escherichia coliUDP-N-acetylmuramoyl:L-alanine ligase (MurC).
Acta Crystallogr.,Sect.D, 62, 2006
1VFE
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HUMAN LACTOFERRIN, N-TERMINAL LOBE MUTANT WITH ARG 121 REPLACED BY SER (R121S)
分子名称: CARBONATE ION, FE (III) ION, HUMAN LACTOFERRIN
著者Faber, H.R, Day, C.L, Baker, E.N.
登録日1996-10-01
公開日1997-04-01
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Mutation of arginine 121 in lactoferrin destabilizes iron binding by disruption of anion binding: crystal structures of R121S and R121E mutants.
Biochemistry, 35, 1996
1VFD
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HUMAN LACTOFERRIN, N-TERMINAL LOBE MUTANT WITH ARG 121 REPLACED BY GLU (R121E)
分子名称: CARBONATE ION, FE (III) ION, LACTOFERRIN
著者Faber, H.R, Day, C.L, Baker, E.N.
登録日1996-10-01
公開日1997-04-21
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mutation of arginine 121 in lactoferrin destabilizes iron binding by disruption of anion binding: crystal structures of R121S and R121E mutants.
Biochemistry, 35, 1996
2VOR
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Crystal Structures of Mycobacterium tuberculosis Folylpolyglutamate Synthase Complexed with ADP and AMPPCP
分子名称: COBALT (II) ION, FOLYLPOLYGLUTAMATE SYNTHASE PROTEIN FOLC, GLYCEROL, ...
著者Young, P.G, Baker, E.N, Metcalf, P, Smith, C.A.
登録日2008-02-19
公開日2008-07-01
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structures of Mycobacterium Tuberculosisfolylpolyglutamate Synthase Complexed with Adp and Amppcp.
Acta Crystallogr.,Sect.D, 64, 2008
1FCK
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STRUCTURE OF DICERIC HUMAN LACTOFERRIN
分子名称: CARBONATE ION, CERIUM (III) ION, LACTOFERRIN
著者Baker, H.M, Baker, C.J, Smith, C.A, Baker, E.N.
登録日2000-07-18
公開日2001-01-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Metal substitution in transferrins: specific binding of cerium(IV) revealed by the crystal structure of cerium-substituted human lactoferrin.
J.Biol.Inorg.Chem., 5, 2000
1LCF
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CRYSTAL STRUCTURE OF COPPER-AND OXALATE-SUBSTITUTED HUMAN LACTOFERRIN AT 2.0 ANGSTROMS RESOLUTION
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, COPPER (II) ION, ...
著者Smith, C.A, Anderson, B.F, Baker, H.M, Baker, E.N.
登録日1994-01-11
公開日1994-08-31
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of copper- and oxalate-substituted human lactoferrin at 2.0 A resolution.
Acta Crystallogr.,Sect.D, 50, 1994
1LFI
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METAL SUBSTITUTION IN TRANSFERRINS: THE CRYSTAL STRUCTURE OF HUMAN COPPER-LACTOFERRIN AT 2.1 ANGSTROMS RESOLUTION
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, COPPER (II) ION, ...
著者Smith, C.A, Anderson, B.F, Baker, H.M, Baker, E.N.
登録日1992-02-10
公開日1993-10-31
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Metal substitution in transferrins: the crystal structure of human copper-lactoferrin at 2.1-A resolution.
Biochemistry, 31, 1992
2VOS
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Mycobacterium tuberculosis Folylpolyglutamate synthase complexed with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, COBALT (II) ION, FOLYLPOLYGLUTAMATE SYNTHASE PROTEIN FOLC, ...
著者Young, P.G, Baker, E.N, Metcalf, P, Smith, C.A.
登録日2008-02-19
公開日2008-07-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of Mycobacterium Tuberculosisfolylpolyglutamate Synthase Complexed with Adp and Amppcp.
Acta Crystallogr.,Sect.D, 64, 2008
2YPQ
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3-deoxy-D-arabino-heptulosonate 7-phosphate synthase with tryptophan and tyrosine bound
分子名称: CHLORIDE ION, GLYCEROL, MANGANESE (II) ION, ...
著者Blackmore, N.J, Reichau, S, Jiao, W, Hutton, R.D, Baker, E.N, Jameson, G.B, Parker, E.J.
登録日2012-10-31
公開日2013-01-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Three Sites and You are Out: Ternary Synergistic Allostery Controls Aromatic Aminoacid Biosynthesis in Mycobacterium Tuberculosis.
J.Mol.Biol., 425, 2013
2Z8L
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Crystal Structure of the Staphylococcal superantigen-like protein SSL5 at pH 4.6 complexed with sialyl Lewis X
分子名称: Exotoxin 3, GLYCEROL, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Baker, H.M, Basu, I, Chung, M.C, Caradoc Davies, T, Fraser, J.D, Baker, E.N.
登録日2007-09-06
公開日2007-11-27
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structures of the staphylococcal toxin SSL5 in complex with sialyl Lewis X reveal a conserved binding site that shares common features with viral and bacterial sialic acid binding proteins
J.Mol.Biol., 374, 2007

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