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4N8Q

Alternative substrates of Mycobacterium tuberculosis anthranilate phosphoribosyl transferase

Summary for 4N8Q
Entry DOI10.2210/pdb4n8q/pdb
Related2BPQ 3QR9 4N5V 4N93
DescriptorAnthranilate phosphoribosyltransferase, 2-amino-4-fluorobenzoic acid (3 entities in total)
Functional Keywordsanthranilate phosphoribosyltransferase, anthranilic acids, magnesium, tryptophan, inhibitor, transferase, magnesium binding phosphoribosyl pyrophosphate
Biological sourceMycobacterium tuberculosis
Total number of polymer chains2
Total formula weight77891.95
Authors
Castell, A.,Cookson, T.V.M.,Bulloch, E.,Evans, G.L.,Baker, E.N.,Lott, J.S.,Parker, E.J. (deposition date: 2013-10-17, release date: 2014-04-23, Last modification date: 2023-09-20)
Primary citationCookson, T.V.,Castell, A.,Bulloch, E.M.,Evans, G.L.,Short, F.L.,Baker, E.N.,Lott, J.S.,Parker, E.J.
Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis.
Biochem.J., 461:87-98, 2014
Cited by
PubMed: 24712732
DOI: 10.1042/BJ20140209
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.08 Å)
Structure validation

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