4N5V

Alternative substrates of Mycobacterium tuberculosis anthranilate phosphoribosyl transferase

Summary for 4N5V

Entry DOI	10.2210/pdb4n5v/pdb
Related	2BPQ 3QR9 4N8Q 4N93
Descriptor	Anthranilate phosphoribosyltransferase, 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, MAGNESIUM ION, ... (6 entities in total)
Functional Keywords	anthranilate phosphoribosyltransferase, anthranilic acids, magnesium, tryptophan, inhibitor, transferase, magnesium binding phosphoribosyl pyrophosphate
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	2
Total formula weight	79355.84
Authors	Castell, A.,Cookson, T.V.M.,Parker, E.J.,Baker, E.N.,Lott, J.S. (deposition date: 2013-10-10, release date: 2014-04-23, Last modification date: 2023-09-20)
Primary citation	Cookson, T.V.,Castell, A.,Bulloch, E.M.,Evans, G.L.,Short, F.L.,Baker, E.N.,Lott, J.S.,Parker, E.J. Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis. Biochem.J., 461:87-98, 2014 Cited by PubMed: 24712732 DOI: 10.1042/BJ20140209 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation