4N5V

Alternative substrates of Mycobacterium tuberculosis anthranilate phosphoribosyl transferase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Anthranilate phosphoribosyltransferase	polymer	378	38790.8	2	UniProt (P66992) Pfam (PF02885) Pfam (PF00591) UniProt (by SIFTS) (P9WFX5) In PDB	Mycobacterium tuberculosis
2	A, B	1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose	non-polymer		390.1	2	Chemie (PRP)
3	A, B	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
4	A, B	2-amino-4-fluorobenzoic acid	non-polymer		155.1	4	Chemie (FA0)
5	A, B	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
6		water	water		18.0	513	Chemie (HOH)

Sequence modifications

A, B: 1 - 370 (UniProt: P66992)

PDB	External Database	Details
Leu 371	-	expression tag
Ala 372	-	expression tag
His 373	-	expression tag
His 374	-	expression tag
His 375	-	expression tag
His 376	-	expression tag
His 377	-	expression tag
His 378	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	77581.7
Non-Polymers*	Number of molecules	13
	Total formula weight	1774.1
All*	Total formula weight	79355.8

*Water molecules are not included.