3RMJ
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![BU of 3rmj by Molmil](/molmil-images/mine/3rmj) | Crystal structure of truncated alpha-Isopropylmalate Synthase from Neisseria meningitidis | 分子名称: | 2-isopropylmalate synthase, GLYCEROL, MAGNESIUM ION, ... | 著者 | Huisman, F.H.A, Baker, H.M, Koon, N, Baker, E.N, Parker, E.J. | 登録日 | 2011-04-20 | 公開日 | 2012-03-14 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Removal of the C-terminal regulatory domain of alpha-isopropylmalate synthase disrupts functional substrate binding Biochemistry, 51, 2012
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4CEV
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![BU of 4cev by Molmil](/molmil-images/mine/4cev) | ARGINASE FROM BACILLUS CALDEVELOX, L-ORNITHINE COMPLEX | 分子名称: | GUANIDINE, L-ornithine, MANGANESE (II) ION, ... | 著者 | Bewley, M.C, Jeffrey, P.D, Patchett, M.L, Kanyo, Z.F, Baker, E.N. | 登録日 | 1999-03-15 | 公開日 | 1999-04-16 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily. Structure Fold.Des., 7, 1999
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3U6W
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![BU of 3u6w by Molmil](/molmil-images/mine/3u6w) | Truncated M. tuberculosis LeuA (1-425) complexed with KIV | 分子名称: | 2-isopropylmalate synthase, 3-METHYL-2-OXOBUTANOIC ACID, GLYCEROL, ... | 著者 | Koon, N, Baker, E.N, Squire, C.J. | 登録日 | 2011-10-13 | 公開日 | 2012-03-14 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Removal of the C-terminal regulatory domain of alpha-isopropylmalate synthase disrupts functional substrate binding. Biochemistry, 51, 2012
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4GEC
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![BU of 4gec by Molmil](/molmil-images/mine/4gec) | Crystal Structure of E.coli MenH R124A Mutant | 分子名称: | 1,2-ETHANEDIOL, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, CHLORIDE ION, ... | 著者 | Johnston, J.M, Baker, E.N, Guo, Z, Jiang, M. | 登録日 | 2012-08-01 | 公開日 | 2013-05-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal Structures of E. coli Native MenH and Two Active Site Mutants. Plos One, 8, 2013
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1OFG
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![BU of 1ofg by Molmil](/molmil-images/mine/1ofg) | GLUCOSE-FRUCTOSE OXIDOREDUCTASE | 分子名称: | GLUCOSE-FRUCTOSE OXIDOREDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Kingston, R.L, Scopes, R.K, Baker, E.N. | 登録日 | 1996-10-17 | 公開日 | 1997-04-21 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The structure of glucose-fructose oxidoreductase from Zymomonas mobilis: an osmoprotective periplasmic enzyme containing non-dissociable NADP. Structure, 4, 1996
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1ND4
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![BU of 1nd4 by Molmil](/molmil-images/mine/1nd4) | Crystal structure of aminoglycoside-3'-phosphotransferase-IIa | 分子名称: | ACETATE ION, Aminoglycoside 3'-phosphotransferase, KANAMYCIN A, ... | 著者 | Nurizzo, D, Shewry, S.C, Baker, E.N, Smith, C.A. | 登録日 | 2002-12-06 | 公開日 | 2003-09-16 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The crystal structure of aminoglycoside-3'-phosphotransferase-IIa, an enzyme responsible for antibiotic resistance J.Mol.Biol., 327, 2003
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1NXJ
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![BU of 1nxj by Molmil](/molmil-images/mine/1nxj) | Structure of Rv3853 from Mycobacterium tuberculosis | 分子名称: | GLYOXYLIC ACID, L(+)-TARTARIC ACID, Probable S-adenosylmethionine:2-demethylmenaquinone methyltransferase | 著者 | Johnston, J.M, Arcus, V.L, Baker, E.N, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2003-02-10 | 公開日 | 2003-07-29 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal Structure of a Putative Methyltransferase from Mycobacterium tuberculosis: Misannotation of a Genome Clarified by Protein Structural Analysis J.Bacteriol., 185, 2003
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1Q7T
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![BU of 1q7t by Molmil](/molmil-images/mine/1q7t) | Rv1170 (MshB) from Mycobacterium tuberculosis | 分子名称: | SULFATE ION, hypothetical protein Rv1170, octyl beta-D-glucopyranoside | 著者 | McCarthy, A.A, Peterson, N.A, Knijff, R, Baker, E.N, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2003-08-20 | 公開日 | 2004-01-13 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal Structure of MshB from Mycobacterium tuberculosis, a Deacetylase Involved in Mycothiol Biosynthesis. J.Mol.Biol., 335, 2004
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5ERX
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![BU of 5erx by Molmil](/molmil-images/mine/5erx) | Crystal Structure of APO MenD from M. tuberculosis - I222 | 分子名称: | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | 著者 | Johnston, J.M, Jirgis, E.N.M, Bashiri, G, Bulloch, E.M.M, Baker, E.N. | 登録日 | 2015-11-16 | 公開日 | 2016-06-22 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.729 Å) | 主引用文献 | Structural Views along the Mycobacterium tuberculosis MenD Reaction Pathway Illuminate Key Aspects of Thiamin Diphosphate-Dependent Enzyme Mechanisms. Structure, 24, 2016
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5ESO
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![BU of 5eso by Molmil](/molmil-images/mine/5eso) | Crystal Structure of M. tuberculosis MenD with ThDP, Mg2+ and Isochorismate bound | 分子名称: | (5S,6S)-5-[(1-carboxyethenyl)oxy]-6-hydroxycyclohexa-1,3-diene-1-carboxylic acid, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, BETA-MERCAPTOETHANOL, ... | 著者 | Johnston, J.M, Jirgis, E.N.M, Bashiri, G, Bulloch, E.M.M, Baker, E.N. | 登録日 | 2015-11-16 | 公開日 | 2016-06-22 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structural Views along the Mycobacterium tuberculosis MenD Reaction Pathway Illuminate Key Aspects of Thiamin Diphosphate-Dependent Enzyme Mechanisms. Structure, 24, 2016
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5ESS
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![BU of 5ess by Molmil](/molmil-images/mine/5ess) | Crystal Structure of M. tuberculosis MenD bound to Mg2+ and covalent intermediate I (a ThDP and decarboxylated 2-oxoglutarate adduct) | 分子名称: | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, 4-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-5-[2-[oxidanyl(phosphonooxy)phosphoryl]oxyethyl]-1,3-thiazol-3 -ium-2-yl]-4-oxidanyl-butanoic acid, ACETATE ION, ... | 著者 | Johnston, J.M, Jirgis, E.N.M, Bashiri, G, Bulloch, E.M.M, Baker, E.N. | 登録日 | 2015-11-17 | 公開日 | 2016-06-22 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural Views along the Mycobacterium tuberculosis MenD Reaction Pathway Illuminate Key Aspects of Thiamin Diphosphate-Dependent Enzyme Mechanisms. Structure, 24, 2016
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5ESU
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![BU of 5esu by Molmil](/molmil-images/mine/5esu) | Crystal Structure of M. tuberculosis MenD bound to Mg2+ and Covalent Intermediate II (a ThDP + de-carboxylated 2-oxoglutarate + Isochorismate adduct) | 分子名称: | (1~{R},2~{S},5~{S},6~{S})-2-[(1~{S})-1-[3-[(4-azanylidene-2-methyl-1~{H}-pyrimidin-5-yl)methyl]-4-methyl-5-[2-[oxidanyl (phosphonooxy)phosphoryl]oxyethyl]-1,3-thiazol-3-ium-2-yl]-1,4-bis(oxidanyl)-4-oxidanylidene-butyl]-6-oxidanyl-5-(3-oxid anyl-3-oxidanylidene-prop-1-en-2-yl)oxy-cyclohex-3-ene-1-carboxylic acid, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, BETA-MERCAPTOETHANOL, ... | 著者 | Johnston, J.M, Jirgis, E.N.M, Bashiri, G, Bulloch, E.M.M, Baker, E.N. | 登録日 | 2015-11-17 | 公開日 | 2016-06-22 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural Views along the Mycobacterium tuberculosis MenD Reaction Pathway Illuminate Key Aspects of Thiamin Diphosphate-Dependent Enzyme Mechanisms. Structure, 24, 2016
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5ERY
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![BU of 5ery by Molmil](/molmil-images/mine/5ery) | Crystal Structure of APO MenD from M. tuberculosis - P212121 | 分子名称: | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | 著者 | Johnston, J.M, Jirgis, E.N.M, Bashiri, G, Bulloch, E.M.M, Baker, E.N. | 登録日 | 2015-11-16 | 公開日 | 2016-06-22 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural Views along the Mycobacterium tuberculosis MenD Reaction Pathway Illuminate Key Aspects of Thiamin Diphosphate-Dependent Enzyme Mechanisms. Structure, 24, 2016
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5ESD
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![BU of 5esd by Molmil](/molmil-images/mine/5esd) | Crystal Structure of M. tuberculosis MenD bound to ThDP and Mn2+ | 分子名称: | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, MANGANESE (II) ION, THIAMINE DIPHOSPHATE | 著者 | Johnston, J.M, Jirgis, E.N.M, Bashiri, G, Bulloch, E.M.M, Baker, E.N. | 登録日 | 2015-11-16 | 公開日 | 2016-06-22 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural Views along the Mycobacterium tuberculosis MenD Reaction Pathway Illuminate Key Aspects of Thiamin Diphosphate-Dependent Enzyme Mechanisms. Structure, 24, 2016
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5BO2
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![BU of 5bo2 by Molmil](/molmil-images/mine/5bo2) | |
5BNE
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![BU of 5bne by Molmil](/molmil-images/mine/5bne) | |
5C1R
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![BU of 5c1r by Molmil](/molmil-images/mine/5c1r) | Stereoisomer of PRPP bound in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyl (AnPRT; trpD) | 分子名称: | 5-O-[(R)-hydroxy(phosphonooxy)phosphoryl]-1-O-phosphono-alpha-D-ribofuranose, Anthranilate phosphoribosyltransferase, GLYCEROL, ... | 著者 | Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2015-06-15 | 公開日 | 2016-07-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.802 Å) | 主引用文献 | Binding and mimicking of the phosphate-rich substrate, PRPP. To Be Published
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5C2L
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![BU of 5c2l by Molmil](/molmil-images/mine/5c2l) | |
5C7S
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![BU of 5c7s by Molmil](/molmil-images/mine/5c7s) | |
5BYT
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![BU of 5byt by Molmil](/molmil-images/mine/5byt) | |
5CEV
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![BU of 5cev by Molmil](/molmil-images/mine/5cev) | ARGINASE FROM BACILLUS CALDEVELOX, L-LYSINE COMPLEX | 分子名称: | GUANIDINE, LYSINE, MANGANESE (II) ION, ... | 著者 | Bewley, M.C, Jeffrey, P.D, Patchett, M.L, Kanyo, Z.F, Baker, E.N. | 登録日 | 1999-03-16 | 公開日 | 1999-04-16 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily. Structure Fold.Des., 7, 1999
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5CYY
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![BU of 5cyy by Molmil](/molmil-images/mine/5cyy) | |
5CW8
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![BU of 5cw8 by Molmil](/molmil-images/mine/5cw8) | Crystal structure of Mycobacterium tuberculosis KstR in complex with 3-oxo-4-cholesten-26-oyl-CoA | 分子名称: | HTH-type transcriptional repressor KstR, S-{1-[5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,7-dihydroxy-6,6-dimethyl-3-oxido-8,12 -dioxo-2,4-dioxa-9,13-diaza-3lambda~5~-phosphapentadecan-15-yl} (2S,6R)-6-[(8S,9S,10R,13R,14S,17R)-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta [a]phenanthren-17-yl]-2-methylheptanethioate (non-preferred name), TRIETHYLENE GLYCOL | 著者 | Ho, N.A.T, Dawes, S, Kendall, S, Casabon, I, Crowe, A.M, Baker, E.N, Eltis, L.D, Lott, J.S, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2015-07-27 | 公開日 | 2016-02-17 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The Structure of the Transcriptional Repressor KstR in Complex with CoA Thioester Cholesterol Metabolites Sheds Light on the Regulation of Cholesterol Catabolism in Mycobacterium tuberculosis. J.Biol.Chem., 291, 2016
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5CXG
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![BU of 5cxg by Molmil](/molmil-images/mine/5cxg) | Crystal structure of Mycobacterium tuberculosis KstR in complex with PEG | 分子名称: | DI(HYDROXYETHYL)ETHER, HTH-type transcriptional repressor KstR, TRIETHYLENE GLYCOL | 著者 | Ho, N.A.T, Dawes, S, Kendall, S, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2015-07-28 | 公開日 | 2016-02-17 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.1001 Å) | 主引用文献 | The Structure of the Transcriptional Repressor KstR in Complex with CoA Thioester Cholesterol Metabolites Sheds Light on the Regulation of Cholesterol Catabolism in Mycobacterium tuberculosis. J.Biol.Chem., 291, 2016
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5CXI
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![BU of 5cxi by Molmil](/molmil-images/mine/5cxi) | Crystal structure of Mycobacterium tuberculosis KstR in complex with 3-oxo-23,24-bisnorchol-4-en-22-oyl-CoA (4-BNC-CoA) | 分子名称: | 3-oxo-23,24-bisnorchol-4-en-22-oyl-CoA, HTH-type transcriptional repressor KstR | 著者 | Ho, N.A.T, Dawes, S, Kendall, S, Casabon, I, Crowe, A.M, Baker, E.N, Eltis, L.D, Lott, J.S, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2015-07-29 | 公開日 | 2016-02-17 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The Structure of the Transcriptional Repressor KstR in Complex with CoA Thioester Cholesterol Metabolites Sheds Light on the Regulation of Cholesterol Catabolism in Mycobacterium tuberculosis. J.Biol.Chem., 291, 2016
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