8SKD
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8SKX
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8SKE
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8SHM
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8SAH
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![BU of 8sah by Molmil](/molmil-images/mine/8sah) | Huntingtin C-HEAT domain in complex with HAP40 | Descriptor: | 40-kDa huntingtin-associated protein, Huntingtin | Authors: | Harding, R.J, Deme, J.C, Alteen, M.G, Arrowsmith, C.H, Lea, S.M, Structural Genomics Consortium (SGC) | Deposit date: | 2023-03-31 | Release date: | 2023-04-26 | Last modified: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Delineation of functional subdomains of Huntingtin protein and their interaction with HAP40. Structure, 31, 2023
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8EOM
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![BU of 8eom by Molmil](/molmil-images/mine/8eom) | TUDOR DOMAIN OF TUMOR SUPPRESSOR P53BP1 WITH MFP-5973 | Descriptor: | 4-(4-methylpiperazine-1-sulfonyl)benzamide, SULFATE ION, TP53-binding protein 1, ... | Authors: | The, J, Hong, Z, Headey, S, Gunzburg, M, Doak, B, James, L.I, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Structural Genomics Consortium (SGC) | Deposit date: | 2022-10-03 | Release date: | 2023-01-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | TUDOR DOMAIN OF TUMOR SUPPRESSOR P53BP1 WITH MFP-5973 to be published
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8F0W
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![BU of 8f0w by Molmil](/molmil-images/mine/8f0w) | Tudor Domain of Tumor suppressor p53BP1 with MFP-5956 | Descriptor: | 1-[4-(4-ethylpiperazin-1-yl)-3-fluorophenyl]butan-1-one, TP53-binding protein 1, UNKNOWN ATOM OR ION | Authors: | The, J, Hong, Z, Dong, A, Headey, S, Gunzburg, M, Doak, B, James, L.I, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Structural Genomics Consortium (SGC) | Deposit date: | 2022-11-04 | Release date: | 2023-01-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Tudor Domain of Tumor suppressor p53BP1 with MFP-5956 to be published
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8FBG
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![BU of 8fbg by Molmil](/molmil-images/mine/8fbg) | Crystal structure of NSD1 Mutant-Y1869C | Descriptor: | CALCIUM ION, Histone-lysine N-methyltransferase, H3 lysine-36 specific, ... | Authors: | Providokhina, K, Dong, A, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2022-11-29 | Release date: | 2023-01-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Crystal structure of NSD1 To Be Published
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8FBH
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![BU of 8fbh by Molmil](/molmil-images/mine/8fbh) | Crystal structure of NSD1 Mutant-T1927A | Descriptor: | Histone-lysine N-methyltransferase, H3 lysine-36 specific, S-ADENOSYLMETHIONINE, ... | Authors: | Providokhina, K, Dong, A, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2022-11-29 | Release date: | 2023-01-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Crystal structure of NSD1 To Be Published
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8F8E
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![BU of 8f8e by Molmil](/molmil-images/mine/8f8e) | Crystal structure of the WDR domain of human DCAF1 in complex with OICR-8268 compound | Descriptor: | (3P)-N-[(1S)-3-amino-1-(3-chloro-4-fluorophenyl)-3-oxopropyl]-3-(4-chloro-2-fluorophenyl)-1H-pyrazole-4-carboxamide, CITRIC ACID, DDB1- and CUL4-associated factor 1 | Authors: | Kimani, S, Li, A, Dong, A, Li, Y, Hutchinson, A, Seitova, A, Wilson, B, Al-Awar, R, Vedadi, M, Brown, P, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC) | Deposit date: | 2022-11-21 | Release date: | 2023-03-01 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Crystal structure of the WDR domain of human DCAF1 in complex with OICR-8268 compound To be published
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7FHJ
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![BU of 7fhj by Molmil](/molmil-images/mine/7fhj) | Crystal structure of BAZ2A with DNA | Descriptor: | Bromodomain adjacent to zinc finger domain protein 2A, DNA (5'-D(*CP*GP*GP*AP*AP*TP*GP*TP*AP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*TP*AP*(5CM)P*AP*TP*TP*CP*CP*G)-3'), ... | Authors: | Liu, K, Dong, A, Li, Y, Loppnau, P, Edwards, A.M, Arrowsmith, C.H, Min, J, Structural Genomics Consortium, Structural Genomics Consortium (SGC) | Deposit date: | 2021-07-29 | Release date: | 2021-12-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Structural basis of the TAM domain of BAZ2A in binding to DNA or RNA independent of methylation status. J.Biol.Chem., 297, 2021
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8G5E
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![BU of 8g5e by Molmil](/molmil-images/mine/8g5e) | Crystal Structure of SETDB1 Tudor domain in complex with UNC6535 | Descriptor: | Histone-lysine N-methyltransferase SETDB1, N~4~-[6-(dimethylamino)hexyl]-N~2~-[5-(dimethylamino)pentyl]-6,7-dimethoxyquinazoline-2,4-diamine, UNKNOWN ATOM OR ION | Authors: | Beldar, S, Dong, A, Brown, P.J, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC) | Deposit date: | 2023-02-13 | Release date: | 2023-02-22 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Crystal Structure of SETDB1 Tudor domain in complex with UNC6535 To be published
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8GCY
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![BU of 8gcy by Molmil](/molmil-images/mine/8gcy) | Co-crystal structure of CBL-B in complex with N-Aryl isoindolin-1-one inhibitor | Descriptor: | 1,2-ETHANEDIOL, 2-{3-[(1s,3R)-3-methyl-1-(4-methyl-4H-1,2,4-triazol-3-yl)cyclobutyl]phenyl}-6-{[(3S)-3-methylpiperidin-1-yl]methyl}-4-(trifluoromethyl)-2,3-dihydro-1H-isoindol-1-one, E3 ubiquitin-protein ligase CBL-B, ... | Authors: | Kimani, S, Zeng, H, Dong, A, Li, Y, Santhakumar, V, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC) | Deposit date: | 2023-03-03 | Release date: | 2023-03-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | The co-crystal structure of Cbl-b and a small-molecule inhibitor reveals the mechanism of Cbl-b inhibition. Commun Biol, 6, 2023
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1RQ6
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![BU of 1rq6 by Molmil](/molmil-images/mine/1rq6) | Solution structure of ribosomal protein S17E from Methanobacterium Thermoautotrophicum, Northeast Structural Genomics Consortium Target TT802 / Ontario Center for Structural Proteomics Target Mth0803 | Descriptor: | 30S ribosomal protein S17e | Authors: | Wu, B, Yee, A, Huang, Y.J, Ramelot, T.A, Semesi, A, Jung, J.W, Edward, A, Lee, W, Kennedy, M.A, Montelione, G.T, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2003-12-04 | Release date: | 2004-12-14 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The solution structure of ribosomal protein S17E from Methanobacterium thermoautotrophicum: a structural homolog of the FF domain. Protein Sci., 17, 2008
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1T57
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![BU of 1t57 by Molmil](/molmil-images/mine/1t57) | Crystal Structure of the Conserved Protein MTH1675 from Methanobacterium thermoautotrophicum | Descriptor: | Conserved Protein MTH1675, FLAVIN MONONUCLEOTIDE, MAGNESIUM ION | Authors: | Kim, Y, Joachimiak, A, Saridakis, V, Xu, X, Arrowsmith, C.H, Christendat, D, Edwards, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2004-05-03 | Release date: | 2004-08-03 | Last modified: | 2018-06-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structure of the Conserved Protein MTH1675 from Methanobacterium thermoautotrophicum To be Published
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1EO0
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![BU of 1eo0 by Molmil](/molmil-images/mine/1eo0) | CONSERVED DOMAIN COMMON TO TRANSCRIPTION FACTORS TFIIS, ELONGIN A, CRSP70 | Descriptor: | TRANSCRIPTION ELONGATION FACTOR S-II | Authors: | Booth, V, Koth, C, Edwards, A.M, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2000-03-21 | Release date: | 2000-05-03 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure of a conserved domain common to the transcription factors TFIIS, elongin A, and CRSP70 J.Biol.Chem., 275, 2000
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1EO1
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1EIW
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1EP0
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![BU of 1ep0 by Molmil](/molmil-images/mine/1ep0) | HIGH RESOLUTION CRYSTAL STRUCTURE OF DTDP-6-DEOXY-D-XYLO-4-HEXULOSE 3,5-EPIMERASE FROM METHANOBACTERIUM THERMOAUTOTROPHICUM | Descriptor: | DTDP-6-DEOXY-D-XYLO-4-HEXULOSE 3,5-EPIMERASE | Authors: | Christendat, D, Saridakis, V, Bochkarev, A, Pai, E.F, Arrowsmith, C.H, Edwards, A.M, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2000-03-24 | Release date: | 2000-12-13 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structure of dTDP-4-keto-6-deoxy-D-hexulose 3,5-epimerase from Methanobacterium thermoautotrophicum complexed with dTDP. J.Biol.Chem., 275, 2000
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1ENW
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1EIK
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![BU of 1eik by Molmil](/molmil-images/mine/1eik) | Solution Structure of RNA Polymerase Subunit RPB5 from Methanobacterium Thermoautotrophicum | Descriptor: | RNA POLYMERASE SUBUNIT RPB5 | Authors: | Yee, A, Booth, V, Dharamsi, A, Engel, A, Edwards, A.M, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2000-02-25 | Release date: | 2000-06-21 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the RNA polymerase subunit RPB5 from Methanobacterium thermoautotrophicum. Proc.Natl.Acad.Sci.USA, 97, 2000
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1EIJ
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![BU of 1eij by Molmil](/molmil-images/mine/1eij) | NMR ENSEMBLE OF METHANOBACTERIUM THERMOAUTOTROPHICUM PROTEIN 1615 | Descriptor: | HYPOTHETICAL PROTEIN MTH1615 | Authors: | Christendat, D, Booth, V, Gernstein, M, Arrowsmith, C.H, Edwards, A.M, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2000-02-25 | Release date: | 2000-11-03 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structural proteomics of an archaeon. Nat.Struct.Biol., 7, 2000
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1EF4
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![BU of 1ef4 by Molmil](/molmil-images/mine/1ef4) | SOLUTION STRUCTURE OF THE ESSENTIAL RNA POLYMERASE SUBUNIT RPB10 FROM METHANOBACTERIUM THERMOAUTOTROPHICUM | Descriptor: | DNA-DIRECTED RNA POLYMERASE, ZINC ION | Authors: | Mackereth, C.D, Arrowsmith, C.H, Edwards, A.M, Mcintosh, L.P, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2000-02-07 | Release date: | 2000-06-14 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Zinc-bundle structure of the essential RNA polymerase subunit RPB10 from Methanobacterium thermoautotrophicum. Proc.Natl.Acad.Sci.USA, 97, 2000
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1NYN
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![BU of 1nyn by Molmil](/molmil-images/mine/1nyn) | Solution NMR Structure of Protein YHR087W from Saccharomyces cerevisiae. Northeast Structural Genomics Consortium Target YTYST425. | Descriptor: | Hypothetical 12.0 kDa protein in NAM8-GAR1 intergenic region | Authors: | Cort, J.R, Yee, A.A, Arrowsmith, C.H, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2003-02-13 | Release date: | 2003-04-08 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The Shwachman-Bodian-Diamond syndrome protein family is involved in RNA metabolism. J.Biol.Chem., 280, 2005
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1O8B
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![BU of 1o8b by Molmil](/molmil-images/mine/1o8b) | Structure of Escherichia coli ribose-5-phosphate isomerase, RpiA, complexed with arabinose-5-phosphate. | Descriptor: | 5-O-phosphono-beta-D-arabinofuranose, RIBOSE 5-PHOSPHATE ISOMERASE | Authors: | Zhang, R.-g, Andersson, C.E, Savchenko, A, Skarina, T, Evdokimova, E, Beasley, S, Arrowsmith, C.H, Edwards, A.M, Joachimiak, A, Mowbray, S.L, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2002-11-26 | Release date: | 2003-01-24 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Structure of Escherichia Coli Ribose-5-Phosphate Isomerase: A Ubiquitous Enzyme of the Pentose Phosphate Pathway and the Calvin Cycle Structure, 11, 2003
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