8G5E

Crystal Structure of SETDB1 Tudor domain in complex with UNC6535

This is a non-PDB format compatible entry.

Summary for 8G5E

• Entry DOI: 10.2210/pdb8g5e/pdb
• Descriptor: Histone-lysine N-methyltransferase SETDB1, N~4~-[6-(dimethylamino)hexyl]-N~2~-[5-(dimethylamino)pentyl]-6,7-dimethoxyquinazoline-2,4-diamine, UNKNOWN ATOM OR ION, ... (4 entities in total)
• Functional Keywords: setdb1, epigenetics, methyllysine reader, sgc, structural genomics, psi:biology, protein structure initiative, structural genomics consortium, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 26798.00

Authors

Beldar, S.,Dong, A.,Brown, P.J.,Arrowsmith, C.H.,Edwards, A.M.,Halabelian, L.,Structural Genomics Consortium (SGC) (deposition date: 2023-02-13, release date: 2023-02-22, Last modification date: 2024-05-22)

• Primary citation: Beldar, S.,Dong, A.,Brown, P.J.,Arrowsmith, C.H.,Edwards, A.M.,Halabelian, L.; Crystal Structure of SETDB1 Tudor domain in complex with UNC6535; To be published,

Experimental method

X-RAY DIFFRACTION (1.98 Å)