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PDB: 4175 件

5VVU
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Structural Investigations of the Substrate Specificity of Human O-GlcNAcase
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Protein O-GlcNAcase, TAB1 peptide
著者Li, B, Jiang, J, Li, H, Hu, C.-W.
登録日2017-05-20
公開日2017-09-27
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural insights into the substrate binding adaptability and specificity of human O-GlcNAcase.
Nat Commun, 8, 2017
1WBZ
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CRYSTAL STRUCTURES OF MURINE MHC CLASS I H-2 Db AND Kb MOLECULES IN COMPLEX WITH CTL EPITOPES FROM INFLUENZA A VIRUS: IMPLICATIONS FOR TCR REPERTOIRE SELECTION AND IMMUNODOMINANCE
分子名称: BETA-2MICROGLOBULIN, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, K-B ALPHA CHAIN PRECURSOR, ...
著者Meijers, R, Lai, C, Yang, Y, Liu, J, Zhong, W, Wang, J, Reinherz, E.L.
登録日2004-11-05
公開日2005-01-19
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structures of Murine Mhc Class I H-2 D(B) and K(B) Molecules in Complex with Ctl Epitopes from Influenza a Virus: Implications for Tcr Repertoire Selection and Immunodominance
J.Mol.Biol., 345, 2005
1WBX
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CRYSTAL STRUCTURES OF MURINE MHC CLASS I H-2 Db AND Kb MOLECULES IN COMPLEX WITH CTL EPITOPES FROM INFLUENZA A VIRUS: IMPLICATIONS FOR TCR REPERTOIRE SELECTION AND IMMUNODOMINANCE
分子名称: BETA-2MICROGLOBULIN, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-B ALPHA CHAIN, ...
著者Meijers, R, Lai, C, Yang, Y, Liu, J, Zhong, W, Wang, J, Reinherz, E.L.
登録日2004-11-05
公開日2005-01-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structures of Murine Mhc Class I H-2 D(B) and K(B) Molecules in Complex with Ctl Epitopes from Influenza a Virus: Implications for Tcr Repertoire Selection and Immunodominance
J.Mol.Biol., 345, 2005
4U20
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Crystal structure of the E. coli ribosome bound to flopristin.
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Noeske, J, Huang, J, Olivier, N.B, Giacobbe, R.A, Zambrowski, M, Cate, J.H.D.
登録日2014-07-16
公開日2014-07-30
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Synergy of streptogramin antibiotics occurs independently of their effects on translation.
Antimicrob.Agents Chemother., 58, 2014
5Z7D
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p204HINab-dsDNA complex structure
分子名称: DNA (5'-D(P*CP*CP*AP*TP*CP*AP*GP*AP*AP*AP*GP*AP*GP*AP*GP*C)-3'), Interferon-activable protein 204
著者Jin, T, Jiang, J, Xiao, T.S.
登録日2018-01-28
公開日2019-01-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献Structural mechanism of DNA recognition by the p204 HIN domain.
Nucleic Acids Res., 2021
3PXG
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Structure of MecA121 and ClpC1-485 complex
分子名称: Adapter protein mecA 1, Negative regulator of genetic competence ClpC/MecB
著者Wang, F, Mei, Z.Q, Wang, J.W, Shi, Y.G.
登録日2010-12-09
公開日2011-03-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.654 Å)
主引用文献Structure and mechanism of the hexameric MecA-ClpC molecular machine.
Nature, 471, 2011
3ID3
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BU of 3id3 by Molmil
Crystal Structure of RseP PDZ2 I304A domain
分子名称: Regulator of sigma E protease
著者Li, X, Wang, B, Feng, L, Wang, J, Shi, Y.
登録日2009-07-20
公開日2009-08-11
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Cleavage of RseA by RseP requires a carboxyl-terminal hydrophobic amino acid following DegS cleavage
Proc.Natl.Acad.Sci.USA, 106, 2009
4QNH
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Calcium-calmodulin (T79D) complexed with the calmodulin binding domain from a small conductance potassium channel SK2-a
分子名称: CALCIUM ION, Calmodulin, SULFATE ION, ...
著者Zhang, M, Pascal, J.M, Logothetis, D.E, Zhang, J.F.
登録日2014-06-17
公開日2014-08-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Selective phosphorylation modulates the PIP2 sensitivity of the CaM-SK channel complex.
Nat.Chem.Biol., 10, 2014
4U27
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Crystal structure of the E. coli ribosome bound to flopristin and linopristin.
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Noeske, J, Huang, J, Olivier, N.B, Giacobbe, R.A, Zambrowski, M, Cate, J.H.D.
登録日2014-07-16
公開日2014-07-30
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Synergy of streptogramin antibiotics occurs independently of their effects on translation.
Antimicrob.Agents Chemother., 58, 2014
4GYY
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Crystal structure of human O-GlcNAc Transferase with UDP-5SGlcNAc and a peptide substrate
分子名称: (2S,3R,4R,5S,6R)-3-(acetylamino)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-thiopyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate, Casein kinase II subunit alpha, SULFATE ION, ...
著者Lazarus, M.B, Jiang, J, Gloster, T.M, Zandberg, W.F, Vocadlo, D.J, Walker, S.
登録日2012-09-05
公開日2012-10-31
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural snapshots of the reaction coordinate for O-GlcNAc transferase.
Nat.Chem.Biol., 8, 2012
4U24
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Crystal structure of the E. coli ribosome bound to dalfopristin.
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Noeske, J, Huang, J, Olivier, N.B, Giacobbe, R.A, Zambrowski, M, Cate, J.H.D.
登録日2014-07-16
公開日2014-07-30
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Synergy of streptogramin antibiotics occurs independently of their effects on translation.
Antimicrob.Agents Chemother., 58, 2014
3KVW
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Crystal Structure of dual-specificity tyrosine phosphorylation regulated kinase 2 (DYRK2) in complex with an indirubin ligand
分子名称: (2Z,3E)-7'-bromo-3-(hydroxyimino)-2'-oxo-1,1',2',3-tetrahydro-2,3'-biindole-5-carboxylic acid, CHLORIDE ION, Dual specificity tyrosine-phosphorylation-regulated kinase 2
著者Filippakopoulos, P, Myrianthopoulos, V, Kritsanida, M, Magiatis, P, Skaltsounis, A.L, Soundararajan, M, Krojer, T, Gileadi, O, Hapka, E, Fedorov, O, Berridge, G, Wang, J, Shrestha, L, Vollmar, M, von Delft, F, Arrowsmith, C.H, Edwards, A, Weigelt, J, Bountra, C, Mikros, E, Knapp, S, Structural Genomics Consortium (SGC)
登録日2009-11-30
公開日2010-01-05
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Crystal Structure of dual-specificity tyrosine phosphorylation regulated kinase 2 (DYRK2) in complex with an indirubin ligand
To be Published
3PZ7
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Crystal structure of Ccd1-DIX domain
分子名称: 1,2-ETHANEDIOL, Dixin
著者Liu, Y.T, Wang, J.W, Chen, L, Wu, J.W.
登録日2010-12-14
公開日2010-12-29
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.441 Å)
主引用文献Molecular basis of WNT Activation via the DIX-domain protein CCD1
To be Published
5Z6P
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The crystal structure of an agarase, AgWH50C
分子名称: B-agarase
著者Mao, X, Zhou, J, Zhang, P, Zhang, L, Zhang, J, Li, Y.
登録日2018-01-24
公開日2019-01-02
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.061 Å)
主引用文献Structure-based design of agarase AgWH50C from Agarivorans gilvus WH0801 to enhance thermostability.
Appl. Microbiol. Biotechnol., 103, 2019
3R62
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Structure of complement regulator Factor H mutant, T1184R.
分子名称: Complement factor H, GLYCEROL
著者Morgan, H.P, Jiang, J, Herbert, A.P, Kavanagh, D, Uhran, D, Barlow, P.N, Hannan, J.P.
登録日2011-03-21
公開日2011-06-29
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Crystallographic determination of the disease-associated T1184R variant of the complement Factor H.
Acta Crystallogr.,Sect.D, 67, 2011
3MWH
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The 1.4 Ang crystal structure of the ArsD arsenic metallochaperone provides insights into its interactions with the ArsA ATPase
分子名称: Arsenical resistance operon trans-acting repressor arsD, GLYCEROL
著者Ye, J, Ajees, A.A, Yang, J, Rosen, B.P.
登録日2010-05-05
公開日2010-05-26
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献The 1.4 A crystal structure of the ArsD arsenic metallochaperone provides insights into its interaction with the ArsA ATPase.
Biochemistry, 49, 2010
3RAU
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Crystal structure of the HD-PTP Bro1 domain
分子名称: 1,2-ETHANEDIOL, ACETATE ION, GLYCEROL, ...
著者Mu, R.L, Jiang, J.S, Snyder, G, Smith, P, Xiao, T.
登録日2011-03-28
公開日2011-09-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The Phe105 Loop of Alix Bro1 Domain Plays a Key Role in HIV-1 Release.
Structure, 19, 2011
1I3C
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RESPONSE REGULATOR FOR CYANOBACTERIAL PHYTOCHROME, RCP1
分子名称: RESPONSE REGULATOR RCP1, SULFATE ION
著者Im, Y.J, Rho, S.-H, Park, C.-M, Yang, S.-S, Kang, J.-G, Lee, J.Y, Song, P.-S, Eom, S.H.
登録日2001-02-14
公開日2002-03-06
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of a cyanobacterial phytochrome response regulator.
Protein Sci., 11, 2002
3R9M
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Crystal structure of the Brox Bro1 domain
分子名称: 1,2-ETHANEDIOL, BRO1 domain-containing protein BROX, FORMIC ACID
著者Mu, R.L, Jiang, J.S, Snyder, G, Smith, P, Xiao, T.
登録日2011-03-25
公開日2011-09-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The Phe105 Loop of Alix Bro1 Domain Plays a Key Role in HIV-1 Release.
Structure, 19, 2011
3NAE
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RB69 DNA Polymerase (Y567A) Ternary Complex with dATP Opposite Guanidinohydantoin
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ...
著者Wang, M, Beckman, J, Blaha, G, Wang, J, Konigsberg, W.H.
登録日2010-06-01
公開日2010-09-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.003 Å)
主引用文献Substitution of Ala for Tyr567 in RB69 DNA Polymerase Allows dAMP and dGMP To Be Inserted opposite Guanidinohydantoin .
Biochemistry, 49, 2010
1R5G
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Crystal Structure of MetAP2 complexed with A311263
分子名称: (2S,3R)-3-AMINO-2-HYDROXY-5-(ETHYLSULFANYL)PENTANOYL-((S)-(-)-(1-NAPHTHYL)ETHYL)AMIDE, MANGANESE (II) ION, Methionine aminopeptidase 2
著者Sheppard, G.S, Wang, J, Kawai, M, BaMaung, N.Y, Craig, R.A, Erickson, S.A, Lynch, L, Patel, J, Yang, F, Searle, X.B, Lou, P, Park, C, Kim, K.H, Henkin, J, Lesniewski, R.
登録日2003-10-10
公開日2004-10-12
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献3-Amino-2-hydroxyamides and related compounds as inhibitors of methionine aminopeptidase-2.
Bioorg.Med.Chem.Lett., 14, 2004
3EFX
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Novel binding site identified in a hybrid between cholera toxin and heat-labile enterotoxin, 1.9A crystal structure reveals the details
分子名称: Cholera enterotoxin subunit B, Heat-labile enterotoxin B chain, alpha-L-fucopyranose-(1-2)-[2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)]beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]beta-D-glucopyranose
著者Holmner, A, Lebens, M, Teneberg, S, Angstrom, J, Okvist, M, Krengel, U.
登録日2008-09-10
公開日2008-09-23
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Novel binding site identified in a hybrid between cholera toxin and heat-labile enterotoxin: 1.9 A crystal structure reveals the details
Structure, 12, 2004
1I5U
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SOLUTION STRUCTURE OF CYTOCHROME B5 TRIPLE MUTANT (E48A/E56A/D60A)
分子名称: CYTOCHROME B5, PROTOPORPHYRIN IX CONTAINING FE
著者Qian, C, Yao, Y, Tang, W, Wang, J, Zhongxian, H.
登録日2001-02-28
公開日2001-03-21
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Effects of charged amino-acid mutation on the solution structure of cytochrome b(5) and binding between cytochrome b(5) and cytochrome c.
Protein Sci., 10, 2001
4EO7
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Crystal structure of the TIR domain of human myeloid differentiation primary response protein 88.
分子名称: MAGNESIUM ION, Myeloid differentiation primary response protein MyD88
著者Snyder, G.A, Cirl, C, Jiang, J.S, Chen, P, Smith, T, Xiao, T.S.
登録日2012-04-13
公開日2013-04-10
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.449 Å)
主引用文献Molecular mechanisms for the subversion of MyD88 signaling by TcpC from virulent uropathogenic Escherichia coli.
Proc.Natl.Acad.Sci.USA, 110, 2013
3OF1
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Crystal Structure of Bcy1, the Yeast Regulatory Subunit of PKA
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, cAMP-dependent protein kinase regulatory subunit
著者Rinaldi, J, Wu, J, Yang, J, Ralston, C.Y, Sankaran, B, Moreno, S, Taylor, S.S.
登録日2010-08-13
公開日2010-12-01
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Structure of Yeast Regulatory Subunit: A Glimpse into the Evolution of PKA Signaling.
Structure, 18, 2010

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