4BZB
 
 | | Crystal structure of the tetrameric dGTP-bound SAMHD1 mutant catalytic core | | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1, MAGNESIUM ION | | 著者 | Ji, X, Yang, H, Wu, Y, Yan, J, Mehrens, J, DeLucia, M, Hao, C, Gronenborn, A.M, Skowronski, J, Ahn, J, Xiong, Y. | | 登録日 | 2013-07-25 | | 公開日 | 2013-10-23 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Mechanism of Allosteric Activation of Samhd1 by Dgtp
Nat.Struct.Mol.Biol., 20, 2013
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6AE3
 | | Crystal structure of GSK3beta complexed with Morin | | 分子名称: | 2-[2,4-bis(oxidanyl)phenyl]-3,5,7-tris(oxidanyl)chromen-4-one, GLYCEROL, Glycogen synthase kinase-3 beta | | 著者 | Kim, K.L, Cha, J.S, Kim, J.S, Ahn, J.S, Ha, N.C, Cho, H.S. | | 登録日 | 2018-08-03 | | 公開日 | 2018-09-19 | | 最終更新日 | 2018-10-03 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Crystal structure of GSK3 beta in complex with the flavonoid, morin
Biochem. Biophys. Res. Commun., 504, 2018
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5YDV
 | | Regulatory domain of HypT from Salmonella typhimurium complexed with HOCl (HOCl-bound form) | | 分子名称: | Cell density-dependent motility repressor, SULFATE ION, hypochlorous acid | | 著者 | Jo, I, Hong, S, Ahn, J, Ha, N.C. | | 登録日 | 2017-09-14 | | 公開日 | 2018-11-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.752 Å) | | 主引用文献 | Structural basis for HOCl recognition and regulation mechanisms of HypT, a hypochlorite-specific transcriptional regulator.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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5YEZ
 | | Regulatory domain of HypT M206Q mutant from Salmonella typhimurium | | 分子名称: | Cell density-dependent motility repressor | | 著者 | Jo, I, Hong, S, Ahn, J, Ha, N.C. | | 登録日 | 2017-09-20 | | 公開日 | 2018-10-03 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural basis for HOCl recognition and regulation mechanisms of HypT, a hypochlorite-specific transcriptional regulator.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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5YDW
 | | Full-length structure of HypT from Salmonella typhimuriuma (hypochlorite-specific LysR-type transcriptional regulator) | | 分子名称: | Cell density-dependent motility repressor | | 著者 | Jo, I, Hong, S, Ahn, J, Ha, N.C. | | 登録日 | 2017-09-15 | | 公開日 | 2018-11-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structural basis for HOCl recognition and regulation mechanisms of HypT, a hypochlorite-specific transcriptional regulator.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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5Y9S
 | | Crystal structure of VV2_1132, a LysR family transcriptional regulator | | 分子名称: | BROMIDE ION, VV2_1132 | | 著者 | Jang, Y, Hong, S, Jo, I, Ahn, J, Ha, N.C. | | 登録日 | 2017-08-28 | | 公開日 | 2018-03-28 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.199 Å) | | 主引用文献 | A Novel Tetrameric Assembly Configuration in VV2_1132, a LysR-Type Transcriptional Regulator inVibrio vulnificus
Mol. Cells, 41, 2018
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5YER
 | | Regulatory domain of HypT from Salmonella typhimurium (Bromide ion-bound) | | 分子名称: | BROMIDE ION, Cell density-dependent motility repressor, SULFATE ION | | 著者 | Jo, I, Hong, S, Ahn, J, Ha, N.C. | | 登録日 | 2017-09-19 | | 公開日 | 2018-11-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | | 主引用文献 | Structural basis for HOCl recognition and regulation mechanisms of HypT, a hypochlorite-specific transcriptional regulator.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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5YDO
 | | Regulatory domain of HypT from Salmonella typhimurium (apo-form) | | 分子名称: | Cell density-dependent motility repressor, SULFATE ION | | 著者 | Jo, I, Hong, S, Ahn, J, Ha, N.C. | | 登録日 | 2017-09-13 | | 公開日 | 2018-11-28 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural basis for HOCl recognition and regulation mechanisms of HypT, a hypochlorite-specific transcriptional regulator.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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5FJB
 | | Cyclophilin A Stabilize HIV-1 Capsid through a Novel Non- canonical Binding Site | | 分子名称: | GAG POLYPROTEIN, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A | | 著者 | Liu, C, Perilla, J.R, Ning, J, Lu, M, Hou, G, Ramalhu, R, Bedwell, G.J, Ahn, J, Shi, J, Gronenborn, A.M, Prevelige Jr, P.E, Rousso, I, Aiken, C, Polenova, T, Schulten, K, Zhang, P. | | 登録日 | 2015-10-07 | | 公開日 | 2016-03-16 | | 最終更新日 | 2017-08-23 | | 実験手法 | ELECTRON MICROSCOPY (9 Å) | | 主引用文献 | Cyclophilin a Stabilizes the HIV-1 Capsid Through a Novel Non-Canonical Binding Site.
Nat.Commun., 7, 2016
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4Z8L
 | | Crystal structure of DCAF1/SIV-MND VPX/MND SAMHD1 NTD ternary complex | | 分子名称: | Protein VPRBP, SAM domain and HD domain-containing protein, Vpx protein, ... | | 著者 | Koharudin, L.M, Wu, Y, Calero, G, Ahn, J, Gronenborn, A.M. | | 登録日 | 2015-04-09 | | 公開日 | 2015-06-17 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural Basis of Clade-specific Engagement of SAMHD1 (Sterile alpha Motif and Histidine/Aspartate-containing Protein 1) Restriction Factors by Lentiviral Viral Protein X (Vpx) Virulence Factors.
J.Biol.Chem., 290, 2015
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5JK7
 | | The X-ray structure of the DDB1-DCAF1-Vpr-UNG2 complex | | 分子名称: | DNA damage-binding protein 1, Protein VPRBP, Protein Vpr, ... | | 著者 | Calero, G, Ahn, J, Wu, Y. | | 登録日 | 2016-04-26 | | 公開日 | 2016-10-05 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (3.49 Å) | | 主引用文献 | The DDB1-DCAF1-Vpr-UNG2 crystal structure reveals how HIV-1 Vpr steers human UNG2 toward destruction.
Nat.Struct.Mol.Biol., 23, 2016
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2KOD
 | | A high-resolution NMR structure of the dimeric C-terminal domain of HIV-1 CA | | 分子名称: | HIV-1 CA C-terminal domain | | 著者 | Byeon, I.-J.L, Jung, J, Ahn, J, concel, J, Gronenborn, A.M. | | 登録日 | 2009-09-18 | | 公開日 | 2009-11-24 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural convergence between Cryo-EM and NMR reveals intersubunit interactions critical for HIV-1 capsid function.
Cell(Cambridge,Mass.), 139, 2009
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3J34
 | | Structure of HIV-1 Capsid Protein by Cryo-EM | | 分子名称: | capsid protein | | 著者 | Zhao, G, Perilla, J.R, Yufenyuy, E, Meng, X, Chen, B, Ning, J, Ahn, J, Gronenborn, A.M, Schulten, K, Aiken, C, Zhang, P. | | 登録日 | 2013-02-23 | | 公開日 | 2013-05-29 | | 最終更新日 | 2018-07-18 | | 実験手法 | ELECTRON MICROSCOPY (8.6 Å) | | 主引用文献 | Mature HIV-1 capsid structure by cryo-electron microscopy and all-atom molecular dynamics.
Nature, 497, 2013
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4QG1
 | | Crystal structure of the tetrameric GTP/dATP-bound SAMHD1 (RN206) mutant catalytic core | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Koharudin, L.M.I, Wu, Y, DeLucia, M, Mehrens, J, Gronenborn, A.M, Ahn, J. | | 登録日 | 2014-05-22 | | 公開日 | 2014-10-15 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural Basis of Allosteric Activation of Sterile alpha Motif and Histidine-Aspartate Domain-containing Protein 1 (SAMHD1) by Nucleoside Triphosphates.
J.Biol.Chem., 289, 2014
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4QFX
 | | Crystal structure of the tetrameric dGTP/dATP-bound SAMHD1 (RN206) mutant catalytic core | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ... | | 著者 | Koharudin, L.M.I, Wu, Y, DeLucia, M, Mehrens, J, Gronenborn, A.M, Ahn, J. | | 登録日 | 2014-05-21 | | 公開日 | 2014-10-15 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural Basis of Allosteric Activation of Sterile alpha Motif and Histidine-Aspartate Domain-containing Protein 1 (SAMHD1) by Nucleoside Triphosphates.
J.Biol.Chem., 289, 2014
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4QG2
 | | Crystal structure of the tetrameric GTP/dATP/ATP-bound SAMHD1 (RN206) mutant catalytic core | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Koharudin, L.M.I, Wu, Y, DeLucia, M, Mehrens, J, Gronenborn, A.M, Ahn, J. | | 登録日 | 2014-05-22 | | 公開日 | 2014-10-15 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structural Basis of Allosteric Activation of Sterile alpha Motif and Histidine-Aspartate Domain-containing Protein 1 (SAMHD1) by Nucleoside Triphosphates.
J.Biol.Chem., 289, 2014
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4QG0
 | | Crystal structure of the tetrameric dGTP/dUTP-bound SAMHD1 (RN206) mutant catalytic core | | 分子名称: | 1,2-ETHANEDIOL, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DEOXYURIDINE-5'-TRIPHOSPHATE, ... | | 著者 | Koharudin, L.M.I, Wu, Y, DeLucia, M, Mehrens, J, Gronenborn, A.M, Ahn, J. | | 登録日 | 2014-05-22 | | 公開日 | 2014-10-15 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural Basis of Allosteric Activation of Sterile alpha Motif and Histidine-Aspartate Domain-containing Protein 1 (SAMHD1) by Nucleoside Triphosphates.
J.Biol.Chem., 289, 2014
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4QG4
 | | Crystal structure of the tetrameric GTP/dATP/ATP-bound SAMHD1 (H210A) mutant catalytic core | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Koharudin, L.M.I, Wu, Y, DeLucia, M, Mehrens, J, Gronenborn, A.M, Ahn, J. | | 登録日 | 2014-05-22 | | 公開日 | 2014-10-15 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural Basis of Allosteric Activation of Sterile alpha Motif and Histidine-Aspartate Domain-containing Protein 1 (SAMHD1) by Nucleoside Triphosphates.
J.Biol.Chem., 289, 2014
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2M65
 | | NMR structure of human restriction factor APOBEC3A | | 分子名称: | Probable DNA dC->dU-editing enzyme APOBEC-3A, ZINC ION | | 著者 | Byeon, I.L, Byeon, C, Ahn, J, Gronenborn, A.M. | | 登録日 | 2013-03-21 | | 公開日 | 2013-05-22 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structure of human restriction factor APOBEC3A reveals substrate binding and enzyme specificity.
Nat Commun, 4, 2013
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7TA8
 | | NMR structure of crosslinked cyclophilin A | | 分子名称: | Peptidyl-prolyl cis-trans isomerase A | | 著者 | Lu, M, Toptygin, D, Xiang, Y, Shi, Y, Schwieters, C.D, Lipinski, E.C, Ahn, J, Byeon, I.-J.L, Gronenborn, A.M. | | 登録日 | 2021-12-20 | | 公開日 | 2022-06-01 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The Magic of Linking Rings: Discovery of a Unique Photoinduced Fluorescent Protein Crosslink.
J.Am.Chem.Soc., 144, 2022
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4QFY
 | | Crystal structure of the tetrameric dGTP/dCTP-bound SAMHD1 (RN206) mutant catalytic core | | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ... | | 著者 | Koharudin, L.M.I, Wu, Y, DeLucia, M, Mehrens, J, Gronenborn, A.M, Ahn, J. | | 登録日 | 2014-05-22 | | 公開日 | 2014-10-15 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural Basis of Allosteric Activation of Sterile alpha Motif and Histidine-Aspartate Domain-containing Protein 1 (SAMHD1) by Nucleoside Triphosphates.
J.Biol.Chem., 289, 2014
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4QFZ
 | | Crystal structure of the tetrameric dGTP/dTTP-bound SAMHD1 (RN206) mutant catalytic core | | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, MAGNESIUM ION, ... | | 著者 | Koharudin, L.M.I, Wu, Y, DeLucia, M, Mehrens, J, Gronenborn, A.M, Ahn, J. | | 登録日 | 2014-05-22 | | 公開日 | 2014-10-15 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural Basis of Allosteric Activation of Sterile alpha Motif and Histidine-Aspartate Domain-containing Protein 1 (SAMHD1) by Nucleoside Triphosphates.
J.Biol.Chem., 289, 2014
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5ZNX
 | | Crystal structure of CM14-treated HlyU from Vibrio vulnificus | | 分子名称: | Transcriptional activator | | 著者 | Park, N, Kim, S, Jo, I, Ahn, J, Hong, S, Jeong, S, Baek, Y. | | 登録日 | 2018-04-11 | | 公開日 | 2019-04-10 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.114 Å) | | 主引用文献 | Small-molecule inhibitor of HlyU attenuates virulence of Vibrio species.
Sci Rep, 9, 2019
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2WEW
 | | Crystal structure of human apoM in complex with myristic acid | | 分子名称: | 1,2-ETHANEDIOL, APOLIPOPROTEIN M, MYRISTIC ACID | | 著者 | Sevvana, M, Ahnstrom, J, Egerer-Sieber, C, Dahlback, B, Muller, Y.A. | | 登録日 | 2009-04-02 | | 公開日 | 2009-09-15 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Serendipitous Fatty Acid Binding Reveals the Structural Determinants for Ligand Recognition in Apolipoprotein M.
J.Mol.Biol., 393, 2009
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7SWL
 | | CryoEM structure of the N-terminal-deleted Rix7 AAA-ATPase | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Kocaman, S, Stanley, R.E, Lo, Y.H, Krahn, J, Dandey, V.P, Sobhany, M, Petrovich, M, Williams, J.G, Deterding, L.J, Borgnia, M.J, Etigunta, S. | | 登録日 | 2021-11-20 | | 公開日 | 2022-03-02 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.88 Å) | | 主引用文献 | Communication network within the essential AAA-ATPase Rix7 drives ribosome assembly.
Pnas Nexus, 1, 2022
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