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PDB: 29 件
2B4X
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Crystal Structure of Antithrombin-III
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antithrombin-III
著者Adams, T.E, Huntington, J.A, Johnson, D.J.D, Bock, S.C.
登録日2005-09-27
公開日2006-10-10
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of Antithrombin-III
To be Published
1N7W
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Crystal Structure of Human Serum Transferrin, N-Lobe L66W mutant
分子名称: CARBONATE ION, FE (III) ION, Serotransferrin
著者Adams, T.E, Mason, A.B, He, Q.Y, Halbrooks, P.J, Briggs, S.K, Smith, V.C, MacGillivray, R.T, Everse, S.J.
登録日2002-11-18
公開日2003-03-18
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Position of Arginine 124 Controls the Rate of Iron Release from the N-lobe of Human Serum Transferrin. A Structural Study
J.Biol.Chem., 278, 2003
1N84
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HUMAN SERUM TRANSFERRIN, N-LOBE
分子名称: CARBONATE ION, FE (III) ION, Serotransferrin
著者Adams, T.E, Mason, A.B, He, Q.Y, Halbrooks, P.J, Briggs, S.K, Smith, V.C, Macgillivray, R.T, Everse, S.J.
登録日2002-11-19
公開日2003-03-18
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献THE POSITION OF ARGININE 124 CONTROLS THE RATE OF IRON RELEASE FROM THE N-LOBE OF HUMAN SERUM TRANSFERRIN. A STRUCTURAL STUDY
J.Biol.Chem., 278, 2003
1N7X
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HUMAN SERUM TRANSFERRIN, N-LOBE Y45E MUTANT
分子名称: CARBONATE ION, FE (III) ION, Serotransferrin
著者Adams, T.E, Mason, A.B, He, Q.Y, Halbrooks, P.J, Briggs, S.K, Smith, V.C, Macgillivray, R.T, Everse, S.J.
登録日2002-11-18
公開日2003-03-18
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献THE POSITION OF ARGININE 124 CONTROLS THE RATE OF IRON RELEASE FROM THE N-LOBE OF HUMAN SERUM TRANSFERRIN. A STRUCTURAL STUDY
J.Biol.Chem., 278, 2003
1SDD
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BU of 1sdd by Molmil
Crystal Structure of Bovine Factor Vai
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COPPER (II) ION, ...
著者Adams, T.E, Hockin, M.F, Mann, K.G, Everse, S.J.
登録日2004-02-13
公開日2004-06-29
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The crystal structure of activated protein C-inactivated bovine factor Va: Implications for cofactor function.
Proc.Natl.Acad.Sci.USA, 101, 2004
3GIS
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BU of 3gis by Molmil
Crystal Structure of Na-free Thrombin in Complex with Thrombomodulin
分子名称: CALCIUM ION, Prothrombin, SULFATE ION, ...
著者Adams, T.E, Huntington, J.A.
登録日2009-03-06
公開日2009-08-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular basis of thrombomodulin activation of slow thrombin
J.Thromb.Haemost., 7, 2009
3K65
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Crystal Structure of Prethombin-2/Fragment-2 Complex
分子名称: 1,4-BUTANEDIOL, Prothrombin
著者Adams, T.E, Huntington, J.A.
登録日2009-10-08
公開日2010-09-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural transitions during prothrombin activation: On the importance of fragment 2.
Biochimie, 122, 2016
4XBM
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BU of 4xbm by Molmil
X-ray crystal structure of Notch ligand Delta-like 1
分子名称: Delta-like protein 1, alpha-L-fucopyranose
著者Kershaw, N.J, Burgess, A.W, Church, N.L, Luo, C.S, Adam, T.E.
登録日2014-12-17
公開日2015-03-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Notch ligand delta-like1: X-ray crystal structure and binding affinity.
Biochem.J., 468, 2015
4V00
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Structural and functional characterization of a novel monotreme- specific protein from the milk of the platypus
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, MONOTREME LACTATING PROTEIN
著者Enjapoori, A.K, Newman, J, Polekina, G, Adams, T.E, Sharp, J.A, Peat, T.S, Nicholas, K.R.
登録日2014-09-10
公開日2015-09-30
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Structural characterization of a novel monotreme-specific protein with antimicrobial activity from the milk of the platypus.
Acta Crystallogr F Struct Biol Commun, 74, 2018
4V3J
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Structural and functional characterization of a novel monotreme- specific protein from the milk of the platypus
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MONOTREME LACTATING PROTEIN
著者Kumar, A, Newman, J, Polekina, G, Adams, T.E, Sharp, J.A, Peat, T.S, Nicholas, K.R.
登録日2014-10-20
公開日2016-01-20
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structural characterization of a novel monotreme-specific protein with antimicrobial activity from the milk of the platypus.
Acta Crystallogr F Struct Biol Commun, 74, 2018
3B9F
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1.6 A structure of the PCI-thrombin-heparin complex
分子名称: 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, GLYCEROL, Plasma serine protease inhibitor, ...
著者Li, W, Adams, T.E, Huntington, J.A.
登録日2007-11-05
公開日2008-04-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Molecular basis of thrombin recognition by protein C inhibitor revealed by the 1.6-A structure of the heparin-bridged complex.
Proc.Natl.Acad.Sci.Usa, 105, 2008
1MOX
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Crystal Structure of Human Epidermal Growth Factor Receptor (residues 1-501) in complex with TGF-alpha
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Garrett, T.P.J, McKern, N.M, Lou, M, Elleman, T.C, Adams, T.E, Lovrecz, G.O, Zhu, H.-J, Walker, F, Frenkel, M.J, Hoyne, P.A, Jorissen, R.N, Nice, E.C, Burgess, A.W, Ward, C.W.
登録日2002-09-10
公開日2003-09-10
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of a Truncated Epidermal Growth Factor Receptor Extracellular Domain Bound to Transforming Growth Factor alpha
Cell(Cambridge,Mass.), 110, 2002
2GD4
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Crystal Structure of the Antithrombin-S195A Factor Xa-Pentasaccharide Complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside, ...
著者Johnson, D.J, Li, W, Adams, T.E, Huntington, J.A.
登録日2006-03-15
公開日2006-05-09
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Antithrombin-S195A factor Xa-heparin structure reveals the allosteric mechanism of antithrombin activation.
Embo J., 25, 2006
2A91
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Crystal structure of ErbB2 domains 1-3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor tyrosine-protein kinase erbB-2
著者Garrett, T.P.J, McKern, N.M, Lou, M, Elleman, T.C, Adams, T.E, Lovrecz, G.O, Kofler, M, Jorissen, R.N, Nice, E.C, Burgess, A.W.
登録日2005-07-11
公開日2005-07-26
最終更新日2022-12-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The Crystal Structure of a Truncated ErbB2 Ectodomain Reveals an Active Conformation, Poised to Interact with Other ErbB Receptors
Mol.Cell, 11, 2003
2AFQ
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1.9 angstrom crystal structure of wild-type human thrombin in the sodium free state
分子名称: GLYCEROL, Prothrombin
著者Johnson, D.J.D, Adams, T.E, Huntington, J.A.
登録日2005-07-26
公開日2005-11-15
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Crystal structure of wild-type human thrombin in the Na+-free state
Biochem.J., 392, 2005
4ZF7
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Crystal structure of ferret interleukin-2
分子名称: DI(HYDROXYETHYL)ETHER, Interleukin 2, PENTAETHYLENE GLYCOL, ...
著者Ren, B, Newman, J, McKinstry, W.J, Adams, T.E.
登録日2015-04-21
公開日2015-11-04
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.893 Å)
主引用文献Structural and functional characterisation of ferret interleukin-2.
Dev.Comp.Immunol., 55, 2015
1RYO
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BU of 1ryo by Molmil
Human serum transferrin, N-lobe bound with oxalate
分子名称: FE (III) ION, OXALATE ION, Serotransferrin
著者Halbrooks, P.J, Mason, A.B, Adams, T.E, Briggs, S.K, Everse, S.J.
登録日2003-12-22
公開日2004-05-11
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献The oxalate effect on release of iron from human serum transferrin explained.
J.Mol.Biol., 339, 2004
2HI9
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Crystal Structure of human native protein C inhibitor
分子名称: CITRIC ACID, GLYCEROL, Plasma serine protease inhibitor
著者Li, W, Adams, T.E, Huntington, J.A.
登録日2006-06-29
公開日2007-03-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of native protein C inhibitor provides insight into its multiple functions.
J.Biol.Chem., 282, 2007
7K09
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Puromycin N-acetyltransferase in complex with acetyl-CoA
分子名称: ACETYL COENZYME *A, Puromycin N-acetyltransferase
著者Caputo, A.T, Newman, J, Adams, T.E, Peat, T.S.
登録日2020-09-03
公開日2021-03-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.313 Å)
主引用文献Structure-guided selection of puromycin N-acetyltransferase mutants with enhanced selection stringency for deriving mammalian cell lines expressing recombinant proteins.
Sci Rep, 11, 2021
7K0A
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Puromycin N-acetyltransferase in complex with acetylated puromycin and CoA
分子名称: 1,2-ETHANEDIOL, COENZYME A, DI(HYDROXYETHYL)ETHER, ...
著者Peat, T.S, Caputo, A.T, Newman, J, Adams, T.E.
登録日2020-09-03
公開日2021-03-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure-guided selection of puromycin N-acetyltransferase mutants with enhanced selection stringency for deriving mammalian cell lines expressing recombinant proteins.
Sci Rep, 11, 2021
6VHI
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Crystal structure of the human ILRUN Fw domain
分子名称: Protein ILRUN
著者Caputo, A.T, Adams, T.E.
登録日2020-01-09
公開日2020-07-01
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Molecular characterisation of ILRUN, a novel inhibitor of proinflammatory and antimicrobial cytokines.
Heliyon, 6, 2020
6B4M
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Structural characterization of a novel monotreme-specific protein from the milk of the platypus
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, IODIDE ION, ...
著者Peat, T.S, Newman, J, Sharp, J.A, Kumar, A, Nicholas, K.R, Adams, T.E.
登録日2017-09-27
公開日2018-01-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural characterization of a novel monotreme-specific protein with antimicrobial activity from the milk of the platypus.
Acta Crystallogr F Struct Biol Commun, 74, 2018
4D70
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Structural, biophysical and biochemical analyses of a Clostridium perfringens Sortase D5 transpeptidase
分子名称: SORTASE FAMILY PROTEIN
著者Suryadinata, R, Seabrook, S, Adams, T.E, Nuttall, S.D, Peat, T.S.
登録日2014-11-19
公開日2015-07-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structural and Biochemical Analyses of a Clostridium Perfringens Sortase D Transpeptidase
Acta Crystallogr.,Sect.D, 71, 2015
4CYY
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The structure of vanin-1: defining the link between metabolic disease, oxidative stress and inflammation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PANTETHEINASE
著者Boersma, Y.L, Newman, J, Adams, T.E, Sparrow, L, Cowieson, N, Lucent, D, Krippner, G, Bozaoglu, K, Peat, T.S.
登録日2014-04-16
公開日2014-12-10
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献The Structure of Vanin-1: A Key Enzyme Linking Metabolic Disease and Inflammation
Acta Crystallogr.,Sect.D, 70, 2014
4CYG
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The structure of vanin-1: defining the link between metabolic disease, oxidative stress and inflammation
分子名称: (2R)-2,4-dihydroxy-N-[(3S)-3-hydroxy-4-phenylbutyl]-3,3-dimethylbutanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Boersma, Y.L, Newman, J, Adams, T.E, Sparrow, L, Cowieson, N, Lucent, D, Krippner, G, Bozaoglu, K, Peat, T.S.
登録日2014-04-11
公開日2014-12-10
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Structure of Vanin-1: A Key Enzyme Linking Metabolic Disease and Inflammation
Acta Crystallogr.,Sect.D, 70, 2014

 

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