7K0A

Puromycin N-acetyltransferase in complex with acetylated puromycin and CoA

Summary for 7K0A

Entry DOI	10.2210/pdb7k0a/pdb
Descriptor	Puromycin N-acetyltransferase, N-Acetylpuromycin, COENZYME A, ... (7 entities in total)
Functional Keywords	enzyme acetyletransferase complex selection marker, antibiotic, transferase
Biological source	Streptomyces alboniger
Total number of polymer chains	2
Total formula weight	48699.96
Authors	Peat, T.S.,Caputo, A.T.,Newman, J.,Adams, T.E. (deposition date: 2020-09-03, release date: 2021-03-17, Last modification date: 2023-10-18)
Primary citation	Caputo, A.T.,Eder, O.M.,Bereznakova, H.,Pothuis, H.,Ardevol, A.,Newman, J.,Nuttall, S.,Peat, T.S.,Adams, T.E. Structure-guided selection of puromycin N-acetyltransferase mutants with enhanced selection stringency for deriving mammalian cell lines expressing recombinant proteins. Sci Rep, 11:5247-5247, 2021 Cited by PubMed: 33664348 DOI: 10.1038/s41598-021-84551-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation