7K0A

Puromycin N-acetyltransferase in complex with acetylated puromycin and CoA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Puromycin N-acetyltransferase	polymer	208	22581.5	2	UniProt (P13249) Pfam (PF00583)	Streptomyces alboniger
2	C, K (A, B)	N-Acetylpuromycin	non-polymer		513.5	2	Chemie (VQ1)
3	D, O (A, B)	COENZYME A	non-polymer		767.5	2	Chemie (COA)
4	E, F (A)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	2	Chemie (PEG)
5	G, H, I, J, P... (A, B)	SULFATE ION	non-polymer		96.1	6	Chemie (SO4)
6	L, M, N (B)	1,2-ETHANEDIOL	non-polymer		62.1	3	Chemie (EDO)
7	R, S (A, B)	water	water		18.0	273	Chemie (HOH)

Sequence modifications

A, B: 2 - 199 (UniProt: P13249)

PDB	External Database	Details
Met -1	-	initiating methionine
Gly 0	-	expression tag
Ser 1	-	expression tag
Ser 200	-	expression tag
His 201	-	expression tag
His 202	-	expression tag
His 203	-	expression tag
His 204	-	expression tag
His 205	-	expression tag
His 206	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	45163.0
Non-Polymers*	Number of molecules	15
	Total formula weight	3537.0
All*	Total formula weight	48700.0

*Water molecules are not included.