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7K09

Puromycin N-acetyltransferase in complex with acetyl-CoA

Summary for 7K09
Entry DOI10.2210/pdb7k09/pdb
DescriptorPuromycin N-acetyltransferase, ACETYL COENZYME *A (3 entities in total)
Functional Keywordsenzyme acetyletransferase complex selection marker, antibiotic, transferase
Biological sourceStreptomyces alboniger
Total number of polymer chains6
Total formula weight140346.37
Authors
Caputo, A.T.,Newman, J.,Adams, T.E.,Peat, T.S. (deposition date: 2020-09-03, release date: 2021-03-17, Last modification date: 2023-10-18)
Primary citationCaputo, A.T.,Eder, O.M.,Bereznakova, H.,Pothuis, H.,Ardevol, A.,Newman, J.,Nuttall, S.,Peat, T.S.,Adams, T.E.
Structure-guided selection of puromycin N-acetyltransferase mutants with enhanced selection stringency for deriving mammalian cell lines expressing recombinant proteins.
Sci Rep, 11:5247-5247, 2021
Cited by
PubMed: 33664348
DOI: 10.1038/s41598-021-84551-9
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.313 Å)
Structure validation

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