2Z9J
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2ZCR
| Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with bisphosphonate BPH-698 | 分子名称: | Dehydrosqualene synthase, MAGNESIUM ION, tripotassium (1R)-4-(4'-butylbiphenyl-4-yl)-1-phosphonatobutane-1-sulfonate | 著者 | Liu, C.I, Jeng, W.Y, Wang, A.H, Oldfield, E. | 登録日 | 2007-11-11 | 公開日 | 2008-03-11 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence. Science, 319, 2008
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2ZEM
| Crystal structure of the human glutaminyl cyclase mutant D248Q at 2.18 angstrom resolution | 分子名称: | Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION | 著者 | Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H. | 登録日 | 2007-12-13 | 公開日 | 2008-04-22 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis. Biochem.J., 411, 2008
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2ZEP
| Crystal structure of the human glutaminyl cyclase mutant H319L at 2.1 angstrom resolution | 分子名称: | Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION | 著者 | Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H. | 登録日 | 2007-12-13 | 公開日 | 2008-04-22 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis. Biochem.J., 411, 2008
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2ZEE
| Crystal structure of the human glutaminyl cyclase mutant S160G at 1.99 angstrom resolution | 分子名称: | Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION | 著者 | Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H. | 登録日 | 2007-12-12 | 公開日 | 2008-04-22 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis. Biochem.J., 411, 2008
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2ZEO
| Crystal structure of the human glutaminyl cyclase mutant D305E at 1.66 angstrom resolution | 分子名称: | Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION | 著者 | Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H. | 登録日 | 2007-12-13 | 公開日 | 2008-04-22 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis. Biochem.J., 411, 2008
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2Z8W
| Structure of an IgNAR-AMA1 complex | 分子名称: | Apical membrane antigen 1, New antigen receptor variable domain | 著者 | Streltsov, V.A, Henderson, K.A, Batchelor, A.H, Coley, A.M, Nuttall, S.D. | 登録日 | 2007-09-11 | 公開日 | 2007-11-27 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Structure of an IgNAR-AMA1 Complex: Targeting a Conserved Hydrophobic Cleft Broadens Malarial Strain Recognition Structure, 15, 2007
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2ZYS
| A. Fulgidus lipase with fatty acid fragment and chloride | 分子名称: | CHLORIDE ION, Lipase, putative, ... | 著者 | Chen, C.K, Ko, T.P, Guo, R.T, Wang, A.H. | 登録日 | 2009-01-29 | 公開日 | 2009-06-16 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structure of the alkalohyperthermophilic Archaeoglobus fulgidus lipase contains a unique C-terminal domain essential for long-chain substrate binding. J.Mol.Biol., 390, 2009
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2ZCQ
| Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with bisphosphonate BPH-652 | 分子名称: | (1R)-4-(3-phenoxyphenyl)-1-phosphonobutane-1-sulfonic acid, Dehydrosqualene synthase, MAGNESIUM ION | 著者 | Liu, C.I, Jeng, W.Y, Wang, A.H, Oldfield, E. | 登録日 | 2007-11-11 | 公開日 | 2008-03-11 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence. Science, 319, 2008
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2ZEF
| Crystal structure of the human glutaminyl cyclase mutant E201D at 1.67 angstrom resolution | 分子名称: | Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION | 著者 | Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H. | 登録日 | 2007-12-12 | 公開日 | 2008-04-22 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis. Biochem.J., 411, 2008
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2ZEL
| Crystal structure of the human glutaminyl cyclase mutant D248A at 1.97 angstrom resolution | 分子名称: | Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION | 著者 | Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H. | 登録日 | 2007-12-13 | 公開日 | 2008-04-22 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis. Biochem.J., 411, 2008
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6NI2
| Stabilized beta-arrestin 1-V2T subcomplex of a GPCR-G protein-beta-arrestin mega-complex | 分子名称: | Beta-arrestin-1, Fab30 Heavy Chain, Fab30 Light Chain, ... | 著者 | Nguyen, A.H, Thomsen, A.R.B, Cahill, T.J, des Georges, A, Lefkowitz, R.J. | 登録日 | 2018-12-26 | 公開日 | 2019-11-20 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structure of an endosomal signaling GPCR-G protein-beta-arrestin megacomplex. Nat.Struct.Mol.Biol., 26, 2019
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2ZCO
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2ZEG
| Crystal structure of the human glutaminyl cyclase mutant E201L at 2.08 angstrom resolution | 分子名称: | Glutaminyl-peptide cyclotransferase, IMIDAZOLE, SULFATE ION, ... | 著者 | Huang, K.F, Wang, Y.R, Chang, E.C, Chou, T.L, Wang, A.H. | 登録日 | 2007-12-12 | 公開日 | 2008-04-22 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | A conserved hydrogen-bond network in the catalytic centre of animal glutaminyl cyclases is critical for catalysis. Biochem.J., 411, 2008
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6NI3
| B2V2R-Gs protein subcomplex of a GPCR-G protein-beta-arrestin mega-complex | 分子名称: | 8-[(1R)-2-{[1,1-dimethyl-2-(2-methylphenyl)ethyl]amino}-1-hydroxyethyl]-5-hydroxy-2H-1,4-benzoxazin-3(4H)-one, Endolysin,Beta-2 adrenergic receptor chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Nguyen, A.H, Thomsen, A.R.B, Cahill, T.J, des Georges, A, Lefkowitz, R.J. | 登録日 | 2018-12-26 | 公開日 | 2019-11-20 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure of an endosomal signaling GPCR-G protein-beta-arrestin megacomplex. Nat.Struct.Mol.Biol., 26, 2019
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3A0K
| Crystal structure of an antiflamatory legume lectin from Cymbosema roseum seeds | 分子名称: | ALPHA-AMINOBUTYRIC ACID, CALCIUM ION, Cymbosema roseum mannose-specific lectin, ... | 著者 | Rocha, B.A.M, Delatorre, P, Marinho, E.S, Benevides, R.G, Moura, T.R, Souza, L.A.G, Nascimento, K.S, Sampaio, A.H, Cavada, B.S. | 登録日 | 2009-03-20 | 公開日 | 2010-04-07 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural basis for both pro- and anti-inflammatory response induced by mannose-specific legume lectin from Cymbosema roseum Biochimie, 2011
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2ZYI
| A. Fulgidus lipase with fatty acid fragment and calcium | 分子名称: | CALCIUM ION, Lipase, putative, ... | 著者 | Chen, C.K, Ko, T.P, Guo, R.T, Wang, A.H. | 登録日 | 2009-01-22 | 公開日 | 2009-06-16 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of the alkalohyperthermophilic Archaeoglobus fulgidus lipase contains a unique C-terminal domain essential for long-chain substrate binding. J.Mol.Biol., 390, 2009
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2ZYH
| mutant A. Fulgidus lipase S136A complexed with fatty acid fragment | 分子名称: | CALCIUM ION, HEXADECANE, Lipase, ... | 著者 | Chen, C.K, Ko, T.P, Guo, R.T, Wang, A.H. | 登録日 | 2009-01-22 | 公開日 | 2009-06-16 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Structure of the alkalohyperthermophilic Archaeoglobus fulgidus lipase contains a unique C-terminal domain essential for long-chain substrate binding. J.Mol.Biol., 390, 2009
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1AWJ
| INTRAMOLECULAR ITK-PROLINE COMPLEX, NMR, MINIMIZED AVERAGE STRUCTURE | 分子名称: | ITK | 著者 | Andreotti, A.H, Bunnell, S.C, Feng, S, Berg, L.J, Schreiber, S.L. | 登録日 | 1997-10-02 | 公開日 | 1998-01-14 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Regulatory intramolecular association in a tyrosine kinase of the Tec family. Nature, 385, 1997
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6DV5
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1B5S
| DIHYDROLIPOYL TRANSACETYLASE (E.C.2.3.1.12) CATALYTIC DOMAIN (RESIDUES 184-425) FROM BACILLUS STEAROTHERMOPHILUS | 分子名称: | DIHYDROLIPOAMIDE ACETYLTRANSFERASE | 著者 | Izard, T, Aevarsson, A, Allen, M.D, Westphal, A.H, Perham, R.N, De Kok, A, Hol, W.G. | 登録日 | 1999-01-10 | 公開日 | 1999-02-16 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (4.4 Å) | 主引用文献 | Principles of quasi-equivalence and Euclidean geometry govern the assembly of cubic and dodecahedral cores of pyruvate dehydrogenase complexes. Proc.Natl.Acad.Sci.USA, 96, 1999
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1BZL
| CRYSTAL STRUCTURE OF TRYPANOSOMA CRUZI TRYPANOTHIONE REDUCTASE IN COMPLEX WITH TRYPANOTHIONE, AND THE STRUCTURE-BASED DISCOVERY OF NEW NATURAL PRODUCT INHIBITORS | 分子名称: | BIS(GAMMA-GLUTAMYL-CYSTEINYL-GLYCINYL)SPERMIDINE, FLAVIN-ADENINE DINUCLEOTIDE, TRYPANOTHIONE REDUCTASE (OXIDIZED FORM) | 著者 | Bond, C.S, Zhang, Y, Berriman, M, Cunningham, M, Fairlamb, A.H, Hunter, W.N. | 登録日 | 1998-11-02 | 公開日 | 1999-11-10 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of Trypanosoma cruzi trypanothione reductase in complex with trypanothione, and the structure-based discovery of new natural product inhibitors. Structure Fold.Des., 7, 1999
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6EF2
| Yeast 26S proteasome bound to ubiquitinated substrate (5T motor state) | 分子名称: | 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, 26S proteasome regulatory subunit 6B homolog, ... | 著者 | de la Pena, A.H, Goodall, E.A, Gates, S.N, Lander, G.C, Martin, A. | 登録日 | 2018-08-15 | 公開日 | 2018-10-17 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.27 Å) | 主引用文献 | Substrate-engaged 26Sproteasome structures reveal mechanisms for ATP-hydrolysis-driven translocation. Science, 362, 2018
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1DEQ
| THE CRYSTAL STRUCTURE OF MODIFIED BOVINE FIBRINOGEN (AT ~4 ANGSTROM RESOLUTION) | 分子名称: | FIBRINOGEN, FIBRINOGEN (ALPHA CHAIN), FIBRINOGEN (BETA CHAIN), ... | 著者 | Brown, J.H, Volkmann, N, Jun, G, Henschen-Edman, A.H, Cohen, C. | 登録日 | 1999-11-15 | 公開日 | 2000-02-02 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | The crystal structure of modified bovine fibrinogen. Proc.Natl.Acad.Sci.USA, 97, 2000
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6EF3
| Yeast 26S proteasome bound to ubiquitinated substrate (4D motor state) | 分子名称: | 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, 26S proteasome regulatory subunit 6B homolog, ... | 著者 | de la Pena, A.H, Goodall, E.A, Gates, S.N, Lander, G.C, Martin, A. | 登録日 | 2018-08-15 | 公開日 | 2018-10-17 | 最終更新日 | 2020-01-08 | 実験手法 | ELECTRON MICROSCOPY (4.17 Å) | 主引用文献 | Substrate-engaged 26Sproteasome structures reveal mechanisms for ATP-hydrolysis-driven translocation. Science, 362, 2018
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