2ZCO

Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus

Summary for 2ZCO

Entry DOI	10.2210/pdb2zco/pdb
Related	2ZCP 2ZCQ 2ZCR 2ZCS
Descriptor	Dehydrosqualene synthase (2 entities in total)
Functional Keywords	crtm, carotenoid biosynthesis, staphyloxanthin biosynthesis, transferase, head-to-head condensation
Biological source	Staphylococcus aureus
Total number of polymer chains	1
Total formula weight	34787.50
Authors	Liu, C.I.,Jeng, W.Y.,Wang, A.H.,Oldfield, E. (deposition date: 2007-11-11, release date: 2008-03-11, Last modification date: 2024-03-13)
Primary citation	Liu, C.I.,Liu, G.Y.,Song, Y.,Yin, F.,Hensler, M.E.,Jeng, W.Y.,Nizet, V.,Wang, A.H.,Oldfield, E. A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence. Science, 319:1391-1394, 2008 Cited by PubMed: 18276850 DOI: 10.1126/science.1153018 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.58 Å)

Structure validation