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PDB: 88758 results

4QPR
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BU of 4qpr by Molmil
CRYSTAL STRUCTURE OF GAF DOMAIN of POTASSIUM SENSOR HISTIDINE KINASE KDPD FROM ESCHERICHIA COLI
Descriptor: Sensor protein KdpD
Authors:Kumar, S, Yernool, D.A.
Deposit date:2014-06-24
Release date:2015-09-02
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal Structure of Gaf Domain of Potassium Sensor Histidine Kinase Kdpd from Escherichia Coli
To be Published
5CAJ
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BU of 5caj by Molmil
Crystal structure of E. coli YaaA, a member of the DUF328/UPF0246 family
Descriptor: BENZAMIDINE, CHLORIDE ION, UPF0246 protein YaaA
Authors:Prahlad, J, Lin, J, Wilson, M.A.
Deposit date:2015-06-29
Release date:2016-02-24
Last modified:2020-10-28
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The DUF328 family member YaaA is a DNA-binding protein with a novel fold.
J.Biol.Chem., 295, 2020
5K30
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BU of 5k30 by Molmil
Crystal structure of methionine gamma-lyase from Citrobacter freundii modified by S-Ethyl-L-cysteine sulfoxide
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, Methionine gamma-lyase, ...
Authors:Revtovich, S.V, Nikulin, A.D, Morozova, E.A, Demidkina, T.V.
Deposit date:2016-05-19
Release date:2017-07-12
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Sulfoxides of sulfur-containing amino acids are suicide substrates of Citrobacter freundii methionine gamma-lyase. Structural bases of the enzyme inactivation.
Biochimie, 168, 2020
5H2O
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BU of 5h2o by Molmil
A three dimensional movie of structural changes in bacteriorhodopsin: structure obtained 250 us after photoexcitation
Descriptor: 2,3-DI-PHYTANYL-GLYCEROL, Bacteriorhodopsin, DECANE, ...
Authors:Royant, A, Nango, E, Nakane, T, Tanaka, T, Arima, T, Neutze, R, Iwata, S.
Deposit date:2016-10-15
Release date:2016-12-21
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A three-dimensional movie of structural changes in bacteriorhodopsin
Science, 354, 2016
6G28
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BU of 6g28 by Molmil
Human [protein ADP-ribosylargenine] hydrolase ARH1 in complex with ADP-ribose
Descriptor: CHLORIDE ION, MAGNESIUM ION, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE, ...
Authors:Ariza, A.
Deposit date:2018-03-22
Release date:2018-11-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.23 Å)
Cite:(ADP-ribosyl)hydrolases: Structural Basis for Differential Substrate Recognition and Inhibition.
Cell Chem Biol, 25, 2018
5MWO
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BU of 5mwo by Molmil
Structure of Mycobacterium Tuberculosis Transcriptional Regulatory Repressor Protein (EthR) in complex with fragment 7E8.
Descriptor: (5-methyl-1-benzothiophen-2-yl)methanol, 1,2-ETHANEDIOL, HTH-type transcriptional regulator EthR
Authors:Mendes, V, Chan, D.S.-H, Thomas, S.E, McConnell, B, Matak-Vinkovic, D, Coyne, A.G, Abell, C, Blundell, T.L.
Deposit date:2017-01-18
Release date:2017-05-31
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.962 Å)
Cite:Fragment Screening against the EthR-DNA Interaction by Native Mass Spectrometry.
Angew. Chem. Int. Ed. Engl., 56, 2017
6G37
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BU of 6g37 by Molmil
Crystal structure of haspin in complex with 5-fluorotubercidin
Descriptor: 5-fluorotubercidin, PHOSPHATE ION, Serine/threonine-protein kinase haspin
Authors:Heroven, C, Chaikuad, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2018-03-24
Release date:2018-04-18
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Halogen-Aromatic pi Interactions Modulate Inhibitor Residence Times.
Angew. Chem. Int. Ed. Engl., 57, 2018
5CLB
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BU of 5clb by Molmil
Alkylpurine DNA glycosylase AlkD bound to DNA containing a 3-methyladenine analog (9-mer A)
Descriptor: AlkD, DNA (5'-D(*AP*AP*GP*CP*AP*(DZM)P*AP*CP*C)-3'), DNA (5'-D(*TP*GP*GP*TP*TP*TP*GP*CP*T)-3')
Authors:Mullins, E.A, Eichman, B.F.
Deposit date:2015-07-16
Release date:2015-10-28
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.766 Å)
Cite:The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions.
Nature, 527, 2015
7PL3
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BU of 7pl3 by Molmil
Crystal structure of catalytic domain in closed conformation of LytB from Streptococcus pneumoniae
Descriptor: CALCIUM ION, DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, ...
Authors:Martinez Caballero, S, Hermoso, J.A.
Deposit date:2021-08-28
Release date:2022-09-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Molecular basis of the final step of cell division in Streptococcus pneumoniae.
Cell Rep, 42, 2023
5H2L
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BU of 5h2l by Molmil
A three dimensional movie of structural changes in bacteriorhodopsin: structure obtained 5.25 us after photoexcitation
Descriptor: 2,3-DI-PHYTANYL-GLYCEROL, Bacteriorhodopsin, DECANE, ...
Authors:Royant, A, Nango, E, Nakane, T, Tanaka, T, Arima, T, Neutze, R, Iwata, S.
Deposit date:2016-10-15
Release date:2016-12-21
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A three-dimensional movie of structural changes in bacteriorhodopsin
Science, 354, 2016
8TIC
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BU of 8tic by Molmil
Structure of human beta 1,3-N-acetylglucosaminyltransferase 2 with compound 1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(2-methylpropyl)-2-oxo-2,3-dihydro-1H-benzimidazole-5-carboxylic acid, CHLORIDE ION, ...
Authors:Sudom, A, Min, X.
Deposit date:2023-07-19
Release date:2023-12-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Imidazolone as an Amide Bioisostere in the Development of beta-1,3- N -Acetylglucosaminyltransferase 2 (B3GNT2) Inhibitors.
J.Med.Chem., 66, 2023
3C92
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BU of 3c92 by Molmil
Thermoplasma acidophilum 20S proteasome with a closed gate
Descriptor: Proteasome subunit alpha, Proteasome subunit beta
Authors:Rabl, J, Smith, D.M, Yu, Y, Chang, S.C, Goldberg, A.L, Cheng, Y.
Deposit date:2008-02-14
Release date:2008-08-05
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:Mechanism of gate opening in the 20S proteasome by the proteasomal ATPases.
Mol.Cell, 30, 2008
5MXZ
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BU of 5mxz by Molmil
Kustc0563 Y40F mutant
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Cytochrome c-552 Ks_3358, ...
Authors:Mohd, A, Barends, T.
Deposit date:2017-01-25
Release date:2018-02-14
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure and Function of the c-type cytochrome Kustc0563 from Kuenenia stuttgartiensis
To Be Published
5CMB
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BU of 5cmb by Molmil
Mnemiopsis leidyi ML032222a iGluR LBD R703K mutant glycine complex
Descriptor: GLYCINE, MAGNESIUM ION, ML032222a iGluR, ...
Authors:Mayer, M.L, Thomas, A.
Deposit date:2015-07-16
Release date:2016-07-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Molecular lock regulates binding of glycine to a primitive NMDA receptor.
Proc.Natl.Acad.Sci.USA, 113, 2016
6PBP
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BU of 6pbp by Molmil
Pseudopaline Dehydrogenase with (S)-Pseudopaline Soaked 1 hour
Descriptor: 1,2-ETHANEDIOL, N-[(1S)-1-carboxy-3-{[(1S)-1-carboxy-2-(1H-imidazol-5-yl)ethyl]amino}propyl]-L-glutamic acid, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:McFarlane, J.S, Lamb, A.L.
Deposit date:2019-06-14
Release date:2019-10-30
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Staphylopine and pseudopaline dehydrogenase from bacterial pathogens catalyze reversible reactions and produce stereospecific metallophores.
J.Biol.Chem., 294, 2019
8TJC
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BU of 8tjc by Molmil
Structure of human beta 1,3-N-acetylglucosaminyltransferase 2 with compound 8a
Descriptor: (6M)-1-[(2R)-3,3-dimethylbutan-2-yl]-6-[(5S)-5-methyl-4-oxo-5-phenyl-4,5-dihydro-1H-imidazol-2-yl]-1,3-dihydro-2H-benzimidazol-2-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Sudom, A, Min, X.
Deposit date:2023-07-20
Release date:2023-12-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Imidazolone as an Amide Bioisostere in the Development of beta-1,3- N -Acetylglucosaminyltransferase 2 (B3GNT2) Inhibitors.
J.Med.Chem., 66, 2023
8HUC
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BU of 8huc by Molmil
Crystal structure of PaIch (Pec1)
Descriptor: GLYCEROL, MaoC_dehydrat_N domain-containing protein, NITRATE ION
Authors:Pramanik, A, Datta, S.
Deposit date:2022-12-23
Release date:2023-12-27
Last modified:2024-06-26
Method:X-RAY DIFFRACTION (1.984 Å)
Cite:Structural and functional insights of itaconyl-CoA hydratase from Pseudomonas aeruginosa highlight a novel N-terminal hotdog fold.
Febs Lett., 598, 2024
8TZE
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BU of 8tze by Molmil
Structure of C-terminal half of LRRK2 bound to GZD-824
Descriptor: 4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}-3-[(1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]benzamide, Leucine-rich repeat serine/threonine-protein kinase 2
Authors:Villagran-Suarez, A, Sanz-Murillo, M, Alegrio-Louro, J, Leschziner, A.
Deposit date:2023-08-26
Release date:2023-12-06
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Inhibition of Parkinson's disease-related LRRK2 by type I and type II kinase inhibitors: Activity and structures.
Sci Adv, 9, 2023
8HPZ
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BU of 8hpz by Molmil
Crystal structure of the MlaD domain of the MlaD protein from Escherichia coli (Form I)
Descriptor: 1,2-ETHANEDIOL, CARBON DIOXIDE, Intermembrane phospholipid transport system binding protein MlaD
Authors:Dutta, A, Kanaujia, S.P.
Deposit date:2022-12-13
Release date:2024-01-10
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Structural Features of MlaD Illuminate its Unique Ligand-Transporting Mechanism and Ancestry.
Protein J., 43, 2024
6CBX
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BU of 6cbx by Molmil
Crystal structure of human SET and MYND Domain Containing protein 2 with MTF1497
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, N-lysine methyltransferase SMYD2, ...
Authors:ZENG, H, DONG, A, Hutchinson, A, Seitova, A, TATLOCK, J, KUMPF, R, OWEN, A, TAYLOR, A, Casimiro-Garcia, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, BROWN, P.J, WU, H, Structural Genomics Consortium (SGC)
Deposit date:2018-02-05
Release date:2018-03-14
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Crystal structure of human SET and MYND Domain Containing protein 2 with MTF1497
to be published
6PBV
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BU of 6pbv by Molmil
Crystal structure of Fab668 complex
Descriptor: 1,2-ETHANEDIOL, Fab668 heavy chain, Fab668 light chain, ...
Authors:Oyen, D, Wilson, I.A.
Deposit date:2019-06-14
Release date:2020-03-04
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.566 Å)
Cite:Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein.
Plos Pathog., 16, 2020
5G5V
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BU of 5g5v by Molmil
Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-038
Descriptor: (4AS,8AR)-4-(3-{4-[(3R)-3-HYDROXYPYRROLIDINE-1-, 1,2-ETHANEDIOL, FORMIC ACID, ...
Authors:Singh, A.K, Brown, D.G.
Deposit date:2016-06-06
Release date:2018-03-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Targeting a Subpocket in Trypanosoma brucei Phosphodiesterase B1 (TbrPDEB1) Enables the Structure-Based Discovery of Selective Inhibitors with Trypanocidal Activity.
J. Med. Chem., 61, 2018
6PD0
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BU of 6pd0 by Molmil
Crystal structure of the bacterial cellulose synthase subunit G (BcsG) from Escherichia coli, catalytic domain
Descriptor: Cellulose biosynthesis protein BcsG, MAGNESIUM ION, ZINC ION
Authors:Anderson, A.C, Brenner, T, Weadge, J.T.
Deposit date:2019-06-18
Release date:2020-03-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:TheEscherichia colicellulose synthase subunit G (BcsG) is a Zn2+-dependent phosphoethanolamine transferase.
J.Biol.Chem., 295, 2020
8TQO
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BU of 8tqo by Molmil
Eukaryotic translation initiation factor 2B tetramer
Descriptor: Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit delta, Translation initiation factor eIF-2B subunit epsilon, ...
Authors:Wang, L, Lawrence, R, Sangwan, S, Anand, A, Shoemaker, S, Deal, A, Marqusee, S, Watler, P.
Deposit date:2023-08-08
Release date:2023-12-06
Last modified:2024-04-10
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:A helical fulcrum in eIF2B coordinates allosteric regulation of stress signaling.
Nat.Chem.Biol., 20, 2024
8HQ9
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BU of 8hq9 by Molmil
Crystal structure of the MlaD domain of the MlaD protein from Escherichia coli (Form II)
Descriptor: CARBON DIOXIDE, Intermembrane phospholipid transport system binding protein MlaD, MAGNESIUM ION
Authors:Dutta, A, Kanaujia, S.P.
Deposit date:2022-12-13
Release date:2024-01-10
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The Structural Features of MlaD Illuminate its Unique Ligand-Transporting Mechanism and Ancestry.
Protein J., 43, 2024

223532

數據於2024-08-07公開中

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