5MWO

Structure of Mycobacterium Tuberculosis Transcriptional Regulatory Repressor Protein (EthR) in complex with fragment 7E8.

Summary for 5MWO

Entry DOI	10.2210/pdb5mwo/pdb
Descriptor	HTH-type transcriptional regulator EthR, (5-methyl-1-benzothiophen-2-yl)methanol, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	ethr, repressor, tetr, mycobacterium tuberculosis, transcription
Biological source	Mycobacterium tuberculosis H37Rv
Total number of polymer chains	1
Total formula weight	25677.82
Authors	Mendes, V.,Chan, D.S.-H.,Thomas, S.E.,McConnell, B.,Matak-Vinkovic, D.,Coyne, A.G.,Abell, C.,Blundell, T.L. (deposition date: 2017-01-18, release date: 2017-05-31, Last modification date: 2024-01-17)
Primary citation	Chan, D.S.,Mendes, V.,Thomas, S.E.,McConnell, B.N.,Matak-Vinkovic, D.,Coyne, A.G.,Blundell, T.L.,Abell, C. Fragment Screening against the EthR-DNA Interaction by Native Mass Spectrometry. Angew. Chem. Int. Ed. Engl., 56:7488-7491, 2017 Cited by PubMed: 28513917 DOI: 10.1002/anie.201702888 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.962 Å)

Structure validation