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PDB: 89346 件

6MN3
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Crystal structure of aminoglycoside acetyltransferase AAC(3)-IVa, apoenzyme
分子名称: Aminoglycoside N(3)-acetyltransferase, AAC(3)-IVa, CHLORIDE ION, ...
著者Stogios, P.J, Evdokimova, E, Wawrzak, Z, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2018-10-01
公開日2018-10-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural and molecular rationale for the diversification of resistance mediated by the Antibiotic_NAT family.
Commun Biol, 5, 2022
7MZZ
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AUGbeta - FAM150A - ALKL1 60-128
分子名称: ALK and LTK ligand 1
著者Rossi, P, Sowaileh, M, Reshetnyak, A.V, Kalodimos, C.G.
登録日2021-05-24
公開日2021-11-24
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Mechanism for the activation of the anaplastic lymphoma kinase receptor.
Nature, 600, 2021
4RPH
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BU of 4rph by Molmil
Crystal structure of Micobacterium tuberculosis UDP-Galactopyranose mutase in complex with substrate UDP-Galp (reduced)
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GALACTOSE-URIDINE-5'-DIPHOSPHATE, UDP-galactopyranose mutase
著者Van Straaten, K.E, Sanders, D.A.R.
登録日2014-10-30
公開日2015-01-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Basis of Ligand Binding to UDP-Galactopyranose Mutase from Mycobacterium tuberculosis Using Substrate and Tetrafluorinated Substrate Analogues.
J.Am.Chem.Soc., 137, 2015
8P5W
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Single particle cryo-EM structure of homohexameric 2-oxoglutarate dehydrogenase OdhA from Corynebacterium glutamicum following reaction with the 2-oxoglutarate analogue succinyl phosphonate
分子名称: (4~{S})-4-[(2~{R})-3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-5-[2-[oxidanyl(phosphonooxy)phosphoryl]oxyethyl]-2~{H}-1,3-thiazol-2-yl]-4-oxidanyl-4-phosphono-butanoic acid, 2-oxoglutarate dehydrogenase E1/E2 component, ACETYL COENZYME *A, ...
著者Yang, L, Mechaly, A.M, Bellinzoni, M.
登録日2023-05-24
公開日2023-08-16
最終更新日2023-08-23
実験手法ELECTRON MICROSCOPY (2.26 Å)
主引用文献High resolution cryo-EM and crystallographic snapshots of the actinobacterial two-in-one 2-oxoglutarate dehydrogenase.
Nat Commun, 14, 2023
5K9O
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BU of 5k9o by Molmil
Crystal structure of multidonor HV1-18+HD3-9 class broadly neutralizing Influenza A antibody 31.b.09 in complex with Hemagglutinin H1 A/California/04/2009
分子名称: 31.b.09 Heavy Fv, 31.b.09 Light Fv, Hemagglutinin, ...
著者Joyce, M.G, Thomas, P.V, Wheatley, A.K, McDermott, A.B, Mascola, J.R, Kwong, P.D.
登録日2016-06-01
公開日2016-12-28
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.387 Å)
主引用文献Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses.
Cell, 166, 2016
8OFT
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BU of 8oft by Molmil
Human adenovirus type 32 fiber-knob protein
分子名称: Fiber
著者Rizkallah, P.J, Parker, A.L, Mundy, R.M, Baker, A.T.
登録日2023-03-16
公開日2023-09-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Broad sialic acid usage amongst species D human adenovirus.
Npj Viruses, 1, 2023
8OFR
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Human adenovirus type 25 fiber-knob protein complexed with sialic acid
分子名称: Fiber, N-acetyl-beta-neuraminic acid
著者Rizkallah, P.J, Parker, A.L, Mundy, R.M, Baker, A.T.
登録日2023-03-16
公開日2023-09-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Broad sialic acid usage amongst species D human adenovirus.
Npj Viruses, 1, 2023
6FDI
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Crystal structure of human phosphodiesterase 4D2 catalytic domain with inhibitor NPD-226
分子名称: 1,2-ETHANEDIOL, 1-[2-[4-[(4~{a}~{S},8~{a}~{R})-4-(3,4-dimethoxyphenyl)-1-oxidanylidene-4~{a},5,8,8~{a}-tetrahydrophthalazin-2-yl]piperi din-1-yl]-2-oxidanylidene-ethyl]-4,4-dimethyl-piperidine-2,6-dione, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Singh, A.K, Brown, D.G.
登録日2017-12-24
公開日2019-04-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献hPDE4D2 structure with inhibitor NPD-226
To be published
5NBU
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BU of 5nbu by Molmil
Crystal structure of native alpha-1-antitrypsin with seven stabilising mutations
分子名称: Alpha-1-antitrypsin, GLYCEROL, OXAMIC ACID
著者Huntington, J.A, Pomowski, A, Johnson, D.J.D.
登録日2017-03-02
公開日2018-03-21
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献CRYSTAL STRUCTURE OF THE Z VARIANT OF ALPHA-1-ANTITRYPSIN REVEALS STRUCTURAL AND DYNAMICAL CHANGES AND SUPPORTS A C-TERMINAL DOMAIN SWAP MECHANISM OF POLYMERIZATION
To Be Published
8P6M
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BU of 8p6m by Molmil
Arsenate reductase (ArsC2) from Deinococcus indicus
分子名称: Low molecular weight phosphatase family protein
著者Gouveia, A.G, Matias, P.M, Romao, C.V.
登録日2023-05-26
公開日2023-08-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Unraveling the multifaceted resilience of arsenic resistant bacterium Deinococcus indicus .
Front Microbiol, 14, 2023
5NIG
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BU of 5nig by Molmil
Crystal structure of HLA-DRB1*04:01 with modified alpha-enolase peptide 326-340 (arginine 327 to citrulline)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Alpha-enolase, HLA class II histocompatibility antigen, ...
著者Gerstner, C, Dubnovitsky, A.
登録日2017-03-24
公開日2018-06-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Memory T cells specific to citrullinated alpha-enolase are enriched in the rheumatic joint.
J. Autoimmun., 92, 2018
7AUG
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BU of 7aug by Molmil
Crystal structure of rsGCamP1.3 in the ON state
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, FORMIC ACID, ...
著者Janowski, R, Fuenzalida-Werner, J.P, Mishra, K, Stiel, A.C, Niessing, D.
登録日2020-11-03
公開日2021-10-27
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Genetically encoded photo-switchable molecular sensors for optoacoustic and super-resolution imaging.
Nat.Biotechnol., 40, 2022
8OFQ
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BU of 8ofq by Molmil
Human adenovirus type 25 fiber-knob protein
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Fiber, ...
著者Rizkallah, P.J, Parker, A.L, Mundy, R.M, Baker, A.T.
登録日2023-03-16
公開日2023-09-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Broad sialic acid usage amongst species D human adenovirus.
Npj Viruses, 1, 2023
8S9Y
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BU of 8s9y by Molmil
Taipan Natriuretic Peptide C -TNPc
分子名称: Peptide TNP-c
著者Torres, A.M, Alewood, P.F.
登録日2023-03-30
公開日2023-04-12
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Taipan Natriuretic Peptides Are Potent and Selective Agonists for the Natriuretic Peptide Receptor A.
Molecules, 28, 2023
6MR7
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BU of 6mr7 by Molmil
DNA polymerase beta substrate complex with templating adenine and incoming Fapy-dGTP analog
分子名称: 1,2-ETHANEDIOL, 1-[2-amino-5-(formylamino)-6-oxo-1,6-dihydropyrimidin-4-yl]-2,5-anhydro-1,3-dideoxy-6-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-D-ribo-hexitol, CALCIUM ION, ...
著者Freudenthal, B.D, Smith, M.R, Wilson, S.H, Beard, W.A.
登録日2018-10-11
公開日2019-01-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.144 Å)
主引用文献A guardian residue hinders insertion of a Fapy•dGTP analog by modulating the open-closed DNA polymerase transition.
Nucleic Acids Res., 47, 2019
6QBZ
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BU of 6qbz by Molmil
Solution structure of the N-terminal domain of the Staphylococcus aureus Hibernation Promoting Factor
分子名称: Ribosome hibernation promoting factor
著者Usachev, K.S, Validov, S.Z, Khusainov, I.S, Klochkov, V.V, Aganov, A.V, Yusupov, M.M.
登録日2018-12-25
公開日2019-06-19
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of the N-terminal domain of the Staphylococcus aureus hibernation promoting factor.
J.Biomol.Nmr, 73, 2019
4S3E
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BU of 4s3e by Molmil
IspG in complex with Inhibitor 7 (compound 1061)
分子名称: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, GLYCEROL, IRON/SULFUR CLUSTER, ...
著者Quitterer, F, Frank, A, Wang, K, Rao, G, O'Dowd, B, Li, J, Guerra, F, Abdel-Azeim, S, Bacher, A, Eppinger, J, Oldfield, E, Groll, M.
登録日2015-01-26
公開日2015-04-29
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Atomic-Resolution Structures of Discrete Stages on the Reaction Coordinate of the [Fe4S4] Enzyme IspG (GcpE).
J.Mol.Biol., 427, 2015
7MZW
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BU of 7mzw by Molmil
Anaplastic lymphoma kinase (ALK) extracellular ligand binding region 673-1025
分子名称: ALK tyrosine kinase receptor
著者Rossi, P, Sowaileh, M, Reshetnyak, A.V, Kalodimos, C.G.
登録日2021-05-24
公開日2021-12-08
最終更新日2021-12-15
実験手法SOLUTION NMR
主引用文献Mechanism for the activation of the anaplastic lymphoma kinase receptor.
Nature, 600, 2021
7PQK
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BU of 7pqk by Molmil
Co-Crystal Structure of M. tuberculosis LeuRS in Complex with the Adduct Formed by Prodrug Cmpd1 with Adenosine-monophosphate
分子名称: (S)-3-(Aminomethyl)-4-chloro-7-(2-hydroxyethoxy)benzo[c][1,2]oxaborol-1(3H)-ol, 1,2-ETHANEDIOL, Leucine--tRNA ligase
著者Palencia, A, Cusack, S.
登録日2021-09-17
公開日2023-01-18
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Adenosine-Dependent Activation Mechanism of Prodrugs Targeting an Aminoacyl-tRNA Synthetase.
J.Am.Chem.Soc., 145, 2023
8C7U
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BU of 8c7u by Molmil
Transcriptional pleiotropic repressor CodY from Enterococcus faecalis in complex with Leu and a 30-bp DNA fragment encompassing two overlapping binding sites
分子名称: DNA (29-MER), DNA (30-MER), GTP-sensing transcriptional pleiotropic repressor CodY, ...
著者Hainzl, T, Sauer-Eriksson, A.E.
登録日2023-01-17
公開日2023-06-28
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Structural insights into CodY activation and DNA recognition.
Nucleic Acids Res., 51, 2023
8OFU
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BU of 8ofu by Molmil
Human adenovirus type 53 fiber-knob protein
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Fiber protein, ...
著者Rizkallah, P.J, Parker, A.L, Mundy, R.M, Baker, A.T.
登録日2023-03-16
公開日2023-09-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Broad sialic acid usage amongst species D human adenovirus.
Npj Viruses, 1, 2023
8OKV
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BU of 8okv by Molmil
lipoprotein BT2095 from Bacteroides thetaiotamicron bound to cyanocobalamin CnCbl
分子名称: CYANOCOBALAMIN, Putative surface layer protein
著者Javier Abellon-Ruiz, J, van den Berg, B, Jana, K, Kleinekathofer, U, Silale, A, Frey, A.M, Basle, A, Trost, M.
登録日2023-03-29
公開日2023-09-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献BtuB TonB-dependent transporters and BtuG surface lipoproteins form stable complexes for vitamin B 12 uptake in gut Bacteroides.
Nat Commun, 14, 2023
4YU7
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BU of 4yu7 by Molmil
Crystal structure of Piratoxin I (PrTX-I) complexed to caffeic acid
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Basic phospholipase A2 homolog piratoxin-1, CAFFEIC ACID, ...
著者Fernandes, C.A.H, Fontes, M.R.M.
登録日2015-03-18
公開日2015-08-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.647 Å)
主引用文献Structural Basis for the Inhibition of a Phospholipase A2-Like Toxin by Caffeic and Aristolochic Acids.
Plos One, 10, 2015
6MUJ
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BU of 6muj by Molmil
Formylglycine generating enzyme bound to copper
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CALCIUM ION, COPPER (II) ION, ...
著者Lafrance-Vanasse, J, Appel, M.J, Tsai, C.-L, Bertozzi, C, Tainer, J.A.
登録日2018-10-23
公開日2019-02-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.249 Å)
主引用文献Formylglycine-generating enzyme binds substrate directly at a mononuclear Cu(I) center to initiate O2activation.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
8OFS
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BU of 8ofs by Molmil
Human adenovirus type 30 fiber-knob protein complexed with sialic acid
分子名称: Fiber, N-acetyl-beta-neuraminic acid
著者Rizkallah, P.J, Parker, A.L, Mundy, R.M, Baker, A.T.
登録日2023-03-16
公開日2023-09-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Broad sialic acid usage amongst species D human adenovirus.
Npj Viruses, 1, 2023

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