6FDI

Crystal structure of human phosphodiesterase 4D2 catalytic domain with inhibitor NPD-226

Summary for 6FDI

• Entry DOI: 10.2210/pdb6fdi/pdb
• Descriptor: cAMP-specific 3',5'-cyclic phosphodiesterase 4D, ZINC ION, MAGNESIUM ION, ... (9 entities in total)
• Functional Keywords: phosphodiesterase, hydrolase, camp hydrolysis, alternative splicing
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 4
• Total formula weight: 174657.86

Authors

Singh, A.K.,Brown, D.G. (deposition date: 2017-12-24, release date: 2019-04-10, Last modification date: 2024-01-17)

• Primary citation: Salado, I.G.,Moreno, C.,Sakaine, G.,Singh, A.K.,Blaazer, A.R.,Siderius, M.,Matheeussen, A.,Gul, S.,Maes, L.,Leurs, R.,Brown, D.G.,Augustyns, K.; hPDE4D2 structure with inhibitor NPD-226; To be published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)