5KH6
 
 | | SETDB1 in complex with a fragment candidate | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... | | 著者 | Walker, J.R, Harding, R.J, Mader, P, Dobrovetsky, E, Dong, A, Collins, P, Pearce, N, Brandao-Neto, J, Douangamath, A, von Delft, F, Brown, P.J, Schapira, M, Arrowsmith, C.H, Edwards, A.M, Santhakumar, V, Structural Genomics Consortium (SGC) | | 登録日 | 2016-06-14 | | 公開日 | 2016-09-21 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | SETDB1 in complex with a fragment candidate
To be published
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5KDV
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6VZV
 | | TTLL6 bound to gamma-elongation analog | | 分子名称: | (2~{S})-2-[[[(3~{R})-3-acetamido-4-oxidanyl-4-oxidanylidene-butyl]-phosphonooxy-phosphoryl]methyl]pentanedioic acid, (2~{S})-2-[[[(3~{S})-3-acetamido-4-oxidanyl-4-oxidanylidene-butyl]-oxidanyl-phosphoryl]methyl]pentanedioic acid, ADENOSINE-5'-DIPHOSPHATE, ... | | 著者 | Mahalingan, K.K, Keenen, E.K, Strickland, M, Li, Y, Liu, Y, Ball, H.L, Tanner, M.E, Tjandra, N, Roll-Mecak, A. | | 登録日 | 2020-02-28 | | 公開日 | 2020-08-12 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | Structural basis for polyglutamate chain initiation and elongation by TTLL family enzymes.
Nat.Struct.Mol.Biol., 27, 2020
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5DDG
 | | The structure of transcriptional factor AraR from Bacteroides thetaiotaomicron VPI in complex with target double strand DNA | | 分子名称: | DNA (27-MER), FORMIC ACID, MALONIC ACID, ... | | 著者 | Chang, C, Tesar, C, Rodionov, D, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2015-08-24 | | 公開日 | 2015-09-09 | | 最終更新日 | 2015-12-16 | | 実験手法 | X-RAY DIFFRACTION (3.06 Å) | | 主引用文献 | A novel transcriptional regulator of L-arabinose utilization in human gut bacteria.
Nucleic Acids Res., 43, 2015
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3ZUL
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2VSG
 | | A Structural Motif in the Variant Surface Glycoproteins of Trypanosoma Brucei | | 分子名称: | VARIANT SURFACE GLYCOPROTEIN ILTAT 1.24 | | 著者 | Blum, M.L, Down, J.A, Metcalf, P, Freymann, D.M, Wiley, D.C. | | 登録日 | 1998-11-19 | | 公開日 | 1998-11-25 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | A structural motif in the variant surface glycoproteins of Trypanosoma brucei.
Nature, 362, 1993
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1ACW
 | | SOLUTION NMR STRUCTURE OF P01, A NATURAL SCORPION PEPTIDE STRUCTURALLY ANALOGOUS TO SCORPION TOXINS SPECIFIC FOR APAMIN-SENSITIVE POTASSIUM CHANNEL, 25 STRUCTURES | | 分子名称: | NATURAL SCORPION PEPTIDE P01 | | 著者 | Blanc, E, Fremont, V, Sizun, P, Meunier, S, Van Rietschoten, J, Thevand, A, Bernassau, J.M, Darbon, H. | | 登録日 | 1997-02-10 | | 公開日 | 1997-04-01 | | 最終更新日 | 2022-02-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of P01, a natural scorpion peptide structurally analogous to scorpion toxins specific for apamin-sensitive potassium channel.
Proteins, 24, 1996
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5CWS
 | | Crystal structure of the intact Chaetomium thermophilum Nsp1-Nup49-Nup57 channel nucleoporin heterotrimer bound to its Nic96 nuclear pore complex attachment site | | 分子名称: | Nucleoporin NIC96, Nucleoporin NSP1, Nucleoporin NUP49, ... | | 著者 | Bley, C.J, Petrovic, S, Paduch, M, Lu, V, Kossiakoff, A.A, Hoelz, A. | | 登録日 | 2015-07-28 | | 公開日 | 2015-10-14 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (3.77 Å) | | 主引用文献 | Architecture of the fungal nuclear pore inner ring complex.
Science, 350, 2015
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3X00
 | | Crystal structure of the core streptavidin mutant V212 (Y22S/N23D/S27D/S45N/Y83S/R84K/E101D/R103K/E116N) complexed with bis iminobiotin long tail (Bis-IMNtail) at 1.3 A resolution | | 分子名称: | 6-({5-[(2E,3aS,4S,6aR)-2-iminohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)hexanoic acid, ETHANE-1,2-DIAMINE, Streptavidin | | 著者 | Kawato, T, Mizohata, E, Shimizu, Y, Meshizuka, T, Yamamoto, T, Takasu, N, Matsuoka, M, Matsumura, H, Kodama, T, Kanai, M, Doi, H, Inoue, T, Sugiyama, A. | | 登録日 | 2014-10-09 | | 公開日 | 2015-01-21 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Structure-based design and synthesis of a bivalent iminobiotin analog showing strong affinity toward a low immunogenic streptavidin mutant.
Biosci.Biotechnol.Biochem., 79, 2015
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6W9M
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4V6D
 | | Crystal structure of the E. coli 70S ribosome in an intermediate state of ratcheting | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Zhang, W, Dunkle, J.A, Cate, J.H.D. | | 登録日 | 2009-06-27 | | 公開日 | 2014-07-09 | | 最終更新日 | 2014-12-10 | | 実験手法 | X-RAY DIFFRACTION (3.814 Å) | | 主引用文献 | Structures of the ribosome in intermediate States of ratcheting.
Science, 325, 2009
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6WAX
 | | C-terminal SH2 domain of p120RasGAP | | 分子名称: | 1,2-ETHANEDIOL, Ras GTPase-activating protein 1, SULFATE ION | | 著者 | Jaber Chehayeb, R, Wang, J, Stiegler, A.L, Boggon, T.J. | | 登録日 | 2020-03-26 | | 公開日 | 2020-06-17 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | The GTPase-activating protein p120RasGAP has an evolutionarily conserved "FLVR-unique" SH2 domain.
J.Biol.Chem., 295, 2020
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3ZDG
 | | Crystal Structure of Ls-AChBP complexed with carbamoylcholine analogue 3-(dimethylamino)butyl dimethylcarbamate (DMABC) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(dimethylamino)butyl dimethylcarbamate, ACETYLCHOLINE BINDING PROTEIN, ... | | 著者 | Ussing, C.A, Hansen, C.P, Petersen, J.G, Jensen, A.A, Rohde, L.A.H, Ahring, P.K, Nielsen, E.O, Kastrup, J.S, Gajhede, M, Frolund, B, Balle, T. | | 登録日 | 2012-11-26 | | 公開日 | 2013-02-20 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Synthesis, Pharmacology, and Biostructural Characterization of Novel Alpha(4)Beta(2) Nicotinic Acetylcholine Receptor Agonists.
J.Med.Chem., 56, 2013
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3ZEV
 | | Structure of Thermostable Agonist-bound Neurotensin Receptor 1 Mutant without Lysozyme Fusion | | 分子名称: | GLYCINE, NEUROTENSIN, NEUROTENSIN RECEPTOR 1 TM86V | | 著者 | Egloff, P, Hillenbrand, M, Schlinkmann, K.M, Batyuk, A, Mittl, P, Plueckthun, A. | | 登録日 | 2012-12-07 | | 公開日 | 2014-01-29 | | 最終更新日 | 2014-02-26 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure of Signaling-Competent Neurotensin Receptor 1 Obtained by Directed Evolution in Escherichia Coli
Proc.Natl.Acad.Sci.USA, 111, 2014
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5KDW
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6W9L
 | | Structure of the Ancestral Glucocorticoid Receptor 2 ligand binding domain in complex with deacetylated deflazacort and PGC1a coregulator fragment | | 分子名称: | (4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-5-hydroxy-6b-(hydroxyacetyl)-4a,6a,8-trimethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]oxazol-2-one, GLYCEROL, Glucocorticoid Receptor, ... | | 著者 | Liu, X, Ortlund, E.A. | | 登録日 | 2020-03-23 | | 公開日 | 2020-11-04 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Disruption of a key ligand-H-bond network drives dissociative properties in vamorolone for Duchenne muscular dystrophy treatment.
Proc.Natl.Acad.Sci.USA, 117, 2020
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5D0J
 | | Grb7 SH2 with inhibitor peptide | | 分子名称: | G7-TEdFP peptide, Growth factor receptor-bound protein 7, PHOSPHATE ION | | 著者 | Gunzburg, M.J, Watson, G.M, Wilce, J.A, Wilce, M.C.J. | | 登録日 | 2015-08-03 | | 公開日 | 2016-06-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7.
Sci Rep, 6, 2016
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2VZP
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4IHQ
 | | Archaellum Assembly ATPase FlaI bound to ADP | | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, FlaI ATPase, ... | | 著者 | Reindl, S, Williams, G.J, Tainer, J.A. | | 登録日 | 2012-12-19 | | 公開日 | 2013-03-06 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Insights into FlaI Functions in Archaeal Motor Assembly and Motility from Structures, Conformations, and Genetics.
Mol.Cell, 49, 2013
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3ZET
 | | Structure of a Salmonella typhimurium YgjD-YeaZ heterodimer. | | 分子名称: | ADENOSINE MONOPHOSPHATE, CADMIUM ION, PROBABLE TRNA THREONYLCARBAMOYLADENOSINE BIOSYNTHESIS PROTEIN GCP, ... | | 著者 | Nichols, C.E, Lamb, H.K, Thompson, P, El Omari, K, Lockyer, M, Charles, I, Hawkins, A.R, Stammers, D.K. | | 登録日 | 2012-12-07 | | 公開日 | 2013-03-20 | | 最終更新日 | 2013-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Crystal Structure of the Dimer of Two Essential Salmonella Typhimurium Proteins, Ygjd & Yeaz and Calorimetric Evidence for the Formation of a Ternary Ygjd-Yeaz-Yjee Complex.
Protein Sci., 22, 2013
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4IP4
 | | Crystal structure of l-fuconate dehydratase from Silicibacter sp. tm1040 liganded with Mg | | 分子名称: | CARBON DIOXIDE, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Fedorov, A.A, Fedorov, E.V, Lukk, T, Gerlt, J.A, Almo, S.C. | | 登録日 | 2013-01-09 | | 公開日 | 2013-12-04 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.128 Å) | | 主引用文献 | Crystal structure of l-fuconate dehydratase from Silicibacter sp. tm1040 liganded with mg
To be Published
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1ACB
 | | CRYSTAL AND MOLECULAR STRUCTURE OF THE BOVINE ALPHA-CHYMOTRYPSIN-EGLIN C COMPLEX AT 2.0 ANGSTROMS RESOLUTION | | 分子名称: | ALPHA-CHYMOTRYPSIN, Eglin C | | 著者 | Bolognesi, M, Frigerio, F, Coda, A, Pugliese, L, Lionetti, C, Menegatti, E, Amiconi, G, Schnebli, H.P, Ascenzi, P. | | 登録日 | 1991-11-08 | | 公開日 | 1993-10-31 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal and molecular structure of the bovine alpha-chymotrypsin-eglin c complex at 2.0 A resolution.
J.Mol.Biol., 225, 1992
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4IJT
 | | Human p53 core domain with hot spot mutation R273H (form II) | | 分子名称: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Cellular tumor antigen p53, ... | | 著者 | Rozenberg, H, Eldar, A, Diskin-Posner, Y, Shakked, Z. | | 登録日 | 2012-12-23 | | 公開日 | 2013-08-14 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Structural studies of p53 inactivation by DNA-contact mutations and its rescue by suppressor mutations via alternative protein-DNA interactions.
Nucleic Acids Res., 41, 2013
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3ZNS
 | | HDAC7 bound with TFMO inhibitor tmp942 | | 分子名称: | HISTONE DEACETYLASE 7, N-{[1-methyl-4-(4-phenyl-1,3-thiazol-2-yl)piperidin-4-yl]methyl}-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide, POTASSIUM ION, ... | | 著者 | Lobera, M, Madauss, K.P, Pohlhaus, D.T, Trump, R.P, Nolan, M.A. | | 登録日 | 2013-02-15 | | 公開日 | 2013-03-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Selective Class Iia Histone Deacetylase Inhibition Via a Non-Chelating Zinc Binding Group
Nat.Chem.Biol., 9, 2013
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4IOS
 | | Structure of phage TP901-1 RBP (ORF49) in complex with nanobody 11. | | 分子名称: | BPP, GLYCEROL, Llama nanobody 11 | | 著者 | Desmyter, A, Farenc, C, Mahony, J, Spinelli, S, Bebeacua, C, Blangy, S, Veesler, D, van Sinderen, D, Cambillau, C. | | 登録日 | 2013-01-08 | | 公開日 | 2013-03-20 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Viral infection modulation and neutralization by camelid nanobodies
Proc.Natl.Acad.Sci.USA, 110, 2013
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