5LF6
 
 | | Human 20S proteasome complex with Z-LLY-ketoaldehyde at 2.1 Angstrom | | 分子名称: | CHLORIDE ION, LLY-ketoaldehyde peptide, MAGNESIUM ION, ... | | 著者 | Schrader, J, Henneberg, F, Mata, R, Tittmann, K, Schneider, T.R, Stark, H, Bourenkov, G, Chari, A. | | 登録日 | 2016-06-30 | | 公開日 | 2016-08-17 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design.
Science, 353, 2016
|
|
6RV9
 | | Crystal Structure of Glucuronoyl Esterase from Cerrena unicolor inactive S270A variant in complex with the aldouronic acid XUXXR | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-O-methyl-alpha-D-glucopyranuronic acid-(1-2)-[beta-D-xylopyranose-(1-4)]beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-Xylitol, ... | | 著者 | Ernst, H.A, Mosbech, C, Langkilde, A, Westh, P, Meyer, A, Agger, J.W, Larsen, S. | | 登録日 | 2019-05-31 | | 公開日 | 2020-03-18 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | The structural basis of fungal glucuronoyl esterase activity on natural substrates.
Nat Commun, 11, 2020
|
|
6OXJ
 | |
7A9A
 | | Crystal structure of rubredoxin B (Rv3250c) from Mycobacterium tuberculosis | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Vakhrameev, D, Kavaleuski, A, Bukhdruker, S, Marin, E, Sushko, T, Grabovec, I.P, Gilep, A, Strushkevich, N, Borshchevskiy, V. | | 登録日 | 2020-09-01 | | 公開日 | 2021-03-03 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.17 Å) | | 主引用文献 | A new twist of rubredoxin function in M. tuberculosis.
Bioorg.Chem., 109, 2021
|
|
4X89
 | | NavMs voltage-gated sodium channal pore and C-terminal domain soaked with Silver nitrate | | 分子名称: | HEGA-10, Ion transport protein, PENTAETHYLENE GLYCOL, ... | | 著者 | Naylor, C.E, Bagneris, C, Wallace, B.A. | | 登録日 | 2014-12-10 | | 公開日 | 2016-03-09 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | Molecular basis of ion permeability in a voltage-gated sodium channel.
Embo J., 35, 2016
|
|
7SBY
 | | Structure of OC43 spike in complex with polyclonal Fab7 (Donor 269) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Human polyclonal Fab model with polyalanine backbone - Heavy chain, ... | | 著者 | Bangaru, S, Antanasijevic, A, Ward, A. | | 登録日 | 2021-09-26 | | 公開日 | 2022-05-04 | | 最終更新日 | 2022-05-18 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural mapping of antibody landscapes to human betacoronavirus spike proteins.
Sci Adv, 8, 2022
|
|
7SBX
 | | Structure of OC43 spike in complex with polyclonal Fab6 (Donor 1051) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Human polyclonal Fab model with polyalanine backbone - Heavy chain, ... | | 著者 | Bangaru, S, Antanasijevic, A, Ward, A. | | 登録日 | 2021-09-26 | | 公開日 | 2022-05-04 | | 最終更新日 | 2022-05-18 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural mapping of antibody landscapes to human betacoronavirus spike proteins.
Sci Adv, 8, 2022
|
|
7SB3
 | | Structure of OC43 spike in complex with polyclonal Fab1 (Donor 269) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Human polyclonal Fab model with polyalanine backbone - Heavy chain, ... | | 著者 | Ward, A, Bangaru, S, Antanasijevic, A. | | 登録日 | 2021-09-23 | | 公開日 | 2022-05-04 | | 最終更新日 | 2022-05-18 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural mapping of antibody landscapes to human betacoronavirus spike proteins.
Sci Adv, 8, 2022
|
|
7S76
 | | HBV CAPSID Y132A WITH COMPOUND 10b AT 2.5A RESOLUTION | | 分子名称: | (1-methyl-1H-1,2,4-triazol-3-yl)methyl {(4S)-1-[(3-chloro-4-fluorophenyl)carbamoyl]-2-methyl-2,4,5,6-tetrahydrocyclopenta[c]pyrrol-4-yl}carbamate, Capsid protein | | 著者 | Olland, A.M, Suto, R.K. | | 登録日 | 2021-09-15 | | 公開日 | 2022-05-04 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The identification of highly efficacious functionalised tetrahydrocyclopenta[ c ]pyrroles as inhibitors of HBV viral replication through modulation of HBV capsid assembly.
Rsc Med Chem, 13, 2022
|
|
7PGU
 | | Autoinhibited structure of human neurofibromin isoform 2 stabilized by Zinc. | | 分子名称: | (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, Neurofibromin, ZINC ION | | 著者 | Naschberger, A, Baradaran, R, Carroni, M, Rupp, B. | | 登録日 | 2021-08-15 | | 公開日 | 2021-11-17 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | The structure of neurofibromin isoform 2 reveals different functional states.
Nature, 599, 2021
|
|
4X8Q
 | | X-ray crystal structure of AlkD2 from Streptococcus mutans | | 分子名称: | CHLORIDE ION, GLYCEROL, PHOSPHATE ION, ... | | 著者 | Mullins, E.A, Shi, R, Eichman, B.F. | | 登録日 | 2014-12-10 | | 公開日 | 2015-05-27 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.729 Å) | | 主引用文献 | A New Family of HEAT-Like Repeat Proteins Lacking a Critical Substrate Recognition Motif Present in Related DNA Glycosylases.
Plos One, 10, 2015
|
|
7SB4
 | | Structure of OC43 spike in complex with polyclonal Fab2 (Donor 1412) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Human polyclonal Fab model with polyalanine backbone - Heavy chain, ... | | 著者 | Bangaru, S, Antanasijevic, A, Ward, A. | | 登録日 | 2021-09-23 | | 公開日 | 2022-05-04 | | 最終更新日 | 2022-05-18 | | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | | 主引用文献 | Structural mapping of antibody landscapes to human betacoronavirus spike proteins.
Sci Adv, 8, 2022
|
|
7AD7
 | | Crystal structure of human complement C5 in complex with the K8 bovine knob domain peptide. | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Macpherson, A, van den Elsen, J.M.H, Schulze, M.E, Birtley, J.R. | | 登録日 | 2020-09-14 | | 公開日 | 2021-03-10 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The allosteric modulation of Complement C5 by knob domain peptides.
Elife, 10, 2021
|
|
7PGT
 | | The structure of human neurofibromin isoform 2 in opened conformation. | | 分子名称: | Neurofibromin, ZINC ION | | 著者 | Naschberger, A, Baradaran, R, Carroni, M, Rupp, B. | | 登録日 | 2021-08-15 | | 公開日 | 2021-11-17 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | The structure of neurofibromin isoform 2 reveals different functional states.
Nature, 599, 2021
|
|
7PGS
 | | Consensus structure of human Neurofibromin isoform 2 | | 分子名称: | Neurofibromin, ZINC ION | | 著者 | Naschberger, A, Baradaran, R, Carroni, M, Rupp, B. | | 登録日 | 2021-08-15 | | 公開日 | 2021-11-17 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | The structure of neurofibromin isoform 2 reveals different functional states.
Nature, 599, 2021
|
|
7SB5
 | | Structure of OC43 spike in complex with polyclonal Fab3 (Donor 1412) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Human polyclonal Fab model with polyalanine backbone - Heavy chain, ... | | 著者 | Bangaru, S, Antanasijevic, A, Ward, A. | | 登録日 | 2021-09-23 | | 公開日 | 2022-05-04 | | 最終更新日 | 2022-05-18 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structural mapping of antibody landscapes to human betacoronavirus spike proteins.
Sci Adv, 8, 2022
|
|
8BHB
 | | GABA-A receptor a5 homomer - a5V3 - RO154513 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid receptor subunit alpha-5, ethyl 8-[(azanylidene-$l^{4}-azanylidene)amino]-5-methyl-6-oxidanylidene-4~{H}-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate | | 著者 | Miller, P.S, Malinauskas, T.M, Hardwick, S.W, Chirgadze, D.Y, Wahid, A.A. | | 登録日 | 2022-10-30 | | 公開日 | 2023-11-01 | | 最終更新日 | 2023-12-27 | | 実験手法 | ELECTRON MICROSCOPY (2.54 Å) | | 主引用文献 | The molecular basis of drug selectivity for alpha 5 subunit-containing GABA A receptors.
Nat.Struct.Mol.Biol., 30, 2023
|
|
7PGR
 | | The structure of human neurofibromin isoform 2 in closed conformation | | 分子名称: | Neurofibromin, ZINC ION | | 著者 | Naschberger, A, Baradaran, R, Carroni, M, Rupp, B. | | 登録日 | 2021-08-15 | | 公開日 | 2021-11-17 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | The structure of neurofibromin isoform 2 reveals different functional states.
Nature, 599, 2021
|
|
7SBV
 | | Structure of OC43 spike in complex with polyclonal Fab4 (Donor 269) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Human polyclonal Fab model with polyalanine backbone - Heavy chain, ... | | 著者 | Bangaru, S, Antanasijevic, A, Ward, A. | | 登録日 | 2021-09-26 | | 公開日 | 2022-05-04 | | 最終更新日 | 2022-05-18 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural mapping of antibody landscapes to human betacoronavirus spike proteins.
Sci Adv, 8, 2022
|
|
8P5R
 | | Crystal structure of full-length, homohexameric 2-oxoglutarate dehydrogenase KGD from Mycobacterium smegmatis in complex with GarA | | 分子名称: | CALCIUM ION, Glycogen accumulation regulator GarA, MAGNESIUM ION, ... | | 著者 | Wagner, T, Mechaly, A.M, Alzari, P.M, Bellinzoni, M. | | 登録日 | 2023-05-24 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (4.562 Å) | | 主引用文献 | High resolution cryo-EM and crystallographic snapshots of the actinobacterial two-in-one 2-oxoglutarate dehydrogenase.
Nat Commun, 14, 2023
|
|
8BHG
 | | GABA-A receptor a5 heteromer - a5V2 - Bretazenil | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Bretazenil, DECYL-BETA-D-MALTOPYRANOSIDE, ... | | 著者 | Miller, P.S, Malinauskas, T.M, Omari, K.E, Aricescu, A.R. | | 登録日 | 2022-10-31 | | 公開日 | 2023-11-15 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | The molecular basis of drug selectivity for alpha 5 subunit-containing GABA A receptors.
Nat.Struct.Mol.Biol., 30, 2023
|
|
5LJX
 | |
7SBW
 | | Structure of OC43 spike in complex with polyclonal Fab5 (Donor 1051) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Human polyclonal Fab model with polyalanine backbone - Heavy chain, ... | | 著者 | Bangaru, S, Antanasijevic, A, Ward, A. | | 登録日 | 2021-09-26 | | 公開日 | 2022-05-04 | | 最終更新日 | 2022-05-18 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural mapping of antibody landscapes to human betacoronavirus spike proteins.
Sci Adv, 8, 2022
|
|
6OHW
 | | Structural basis for human coronavirus attachment to sialic acid receptors. Apo-HCoV-OC43 S | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike surface glycoprotein, ... | | 著者 | Tortorici, M.A, Walls, A.C, Lang, Y, Wang, C, Li, Z, Koerhuis, D, Boons, G.J, Bosch, B.J, Rey, F.A, de Groot, R, Veesler, D. | | 登録日 | 2019-04-07 | | 公開日 | 2019-06-05 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural basis for human coronavirus attachment to sialic acid receptors.
Nat.Struct.Mol.Biol., 26, 2019
|
|
6TZU
 | | Dihydrodipicolinate synthase (DHDPS) from C.jejuni, N84A mutant with pyruvate bound in the active site | | 分子名称: | 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, ACETATE ION, ... | | 著者 | Saran, S, Majdi Yazdi, M, Lehnert, C, Palmer, D.R.J, Sanders, D.A.R. | | 登録日 | 2019-08-13 | | 公開日 | 2019-12-04 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Asparagine-84, a regulatory allosteric site residue, helps maintain the quaternary structure of Campylobacter jejuni dihydrodipicolinate synthase.
J.Struct.Biol., 209, 2020
|
|
