7U6Z
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![BU of 7u6z by Molmil](/molmil-images/mine/7u6z) | Pertussis toxin E129D NAD | 分子名称: | IODIDE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Pertussis toxin subunit 1 | 著者 | Littler, D.R, Beddoe, T, Pulliainen, A, Rossjohn, J. | 登録日 | 2022-03-06 | 公開日 | 2022-04-13 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.30002 Å) | 主引用文献 | Crystal structures of pertussis toxin with NAD + and analogs provide structural insights into the mechanism of its cytosolic ADP-ribosylation activity. J.Biol.Chem., 298, 2022
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8QA3
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5LX8
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![BU of 5lx8 by Molmil](/molmil-images/mine/5lx8) | Crystal structure of BT1762 | 分子名称: | SODIUM ION, SULFATE ION, SusD homolog | 著者 | Basle, A. | 登録日 | 2016-09-20 | 公開日 | 2016-12-14 | 最終更新日 | 2017-08-30 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Structural basis for nutrient acquisition by dominant members of the human gut microbiota. Nature, 541, 2017
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6RO5
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6QMM
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![BU of 6qmm by Molmil](/molmil-images/mine/6qmm) | Crystal structure of Synecochoccus Spermidine Synthase in complex with putrescine, spermidine and MTA | 分子名称: | (2S)-1-[3-{[(2R)-2-hydroxypropyl]oxy}-2,2-bis({[(2R)-2-hydroxypropyl]oxy}methyl)propoxy]propan-2-ol, 1,4-DIAMINOBUTANE, 5'-DEOXY-5'-METHYLTHIOADENOSINE, ... | 著者 | Guedez, G, Pothipongsa, A, Incharoensakdi, A, Salminen, T.A. | 登録日 | 2019-02-07 | 公開日 | 2019-03-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Crystal structure of dimericSynechococcusspermidine synthase with bound polyamine substrate and product. Biochem.J., 476, 2019
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7ADO
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![BU of 7ado by Molmil](/molmil-images/mine/7ado) | Cryo-EM structure of human ER membrane protein complex in lipid nanodiscs | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ER membrane protein complex subunit 1, ... | 著者 | Braeuning, B, Prabu, J.R, Miller-Vedam, L.E, Weissman, J.S, Frost, A, Schulman, B.A. | 登録日 | 2020-09-15 | 公開日 | 2020-12-02 | 最終更新日 | 2021-01-20 | 実験手法 | ELECTRON MICROSCOPY (3.39 Å) | 主引用文献 | Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients. Elife, 9, 2020
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8QUZ
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![BU of 8quz by Molmil](/molmil-images/mine/8quz) | Crystal structure of chlorite dismutase at 3000 eV based on analytical absorption corrections | 分子名称: | CHLORIDE ION, Chlorite Dismutase, GLYCEROL, ... | 著者 | Duman, R, Wagner, A, Kamps, J, Orville, A. | 登録日 | 2023-10-17 | 公開日 | 2024-07-03 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Ray-tracing analytical absorption correction for X-ray crystallography based on tomographic reconstructions. J.Appl.Crystallogr., 57, 2024
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6TXJ
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![BU of 6txj by Molmil](/molmil-images/mine/6txj) | Crystal structure of thermotoga maritima A42V E65D Ferritin | 分子名称: | EICOSANE, FE (III) ION, Ferritin, ... | 著者 | Wilk, P, Grudnik, P, Kumar, M, Heddle, J, Chakraborti, S, Biela, A.P. | 登録日 | 2020-01-14 | 公開日 | 2021-07-28 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | A single residue can modulate nanocage assembly in salt dependent ferritin. Nanoscale, 13, 2021
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5NRM
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![BU of 5nrm by Molmil](/molmil-images/mine/5nrm) | Crystal structure of the sixth cohesin from Acetivibrio cellulolyticus' scaffoldin B in complex with Cel5 dockerin S51I, L52N mutant | 分子名称: | CALCIUM ION, DocCel5: Type I dockerin repeat domain from A. cellulolyticus family 5 endoglucanase WP_010249057 S51I, L52N mutant, ... | 著者 | Bule, P, Najmudin, S, Fontes, C.M.G.A, Alves, V.D. | 登録日 | 2017-04-24 | 公開日 | 2018-01-31 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structure-function analyses generate novel specificities to assemble the components of multienzyme bacterial cellulosome complexes. J. Biol. Chem., 293, 2018
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6QNN
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6QNP
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6ZN6
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![BU of 6zn6 by Molmil](/molmil-images/mine/6zn6) | Protein polybromo-1 (PB1 BD2) Bound To MW278 | 分子名称: | 1,2-ETHANEDIOL, 2-[6-azanyl-5-[(3~{R})-3-phenoxypiperidin-1-yl]pyridazin-3-yl]phenol, Protein polybromo-1 | 著者 | Preuss, F, Mathea, S, Chatterjee, D, Wanior, M, Joerger, A.C, Knapp, S. | 登録日 | 2020-07-06 | 公開日 | 2020-08-26 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Pan-SMARCA/PB1 Bromodomain Inhibitors and Their Role in Regulating Adipogenesis. J.Med.Chem., 63, 2020
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8R2H
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![BU of 8r2h by Molmil](/molmil-images/mine/8r2h) | Cryo-EM structure of 1-deoxy-D-xylulose 5-phosphate synthase (DXPS) from Plasmodium falciparum | 分子名称: | 1-deoxy-D-xylulose-5-phosphate synthase, MAGNESIUM ION, THIAMINE DIPHOSPHATE | 著者 | Gawriljuk, V.O, Godoy, A.S, Oerlemans, R, Groves, M.R. | 登録日 | 2023-11-06 | 公開日 | 2024-06-12 | 最終更新日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (2.42 Å) | 主引用文献 | Cryo-EM structure of 1-deoxy-D-xylulose 5-phosphate synthase DXPS from Plasmodium falciparum reveals a distinct N-terminal domain. Nat Commun, 15, 2024
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8UZT
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![BU of 8uzt by Molmil](/molmil-images/mine/8uzt) | Mitochondrial single-stranded binding protein bound to DNA | 分子名称: | GLYCEROL, SODIUM ION, Single-stranded DNA-binding protein, ... | 著者 | Riccio, A.A, Pedersen, L.C, Bouvette, J, Borgnia, J.M, Copeland, W.C. | 登録日 | 2023-11-16 | 公開日 | 2024-08-21 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structures of the mitochondrial single-stranded DNA binding protein with DNA and DNA polymerase gamma. Nucleic Acids Res., 2024
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6ZPH
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![BU of 6zph by Molmil](/molmil-images/mine/6zph) | Kinesin binding protein complexed with Kif15 motor domain | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, KIF-binding protein, Kinesin-like protein KIF15, ... | 著者 | Atherton, J, Hummel, J.J.A, Olieric, N, Locke, J, Pena, A, Rosenfeld, S.S, Steinmetz, M.O, Hoogenraad, C.C, Moores, C.A. | 登録日 | 2020-07-08 | 公開日 | 2020-12-30 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (6.9 Å) | 主引用文献 | The mechanism of kinesin inhibition by kinesin-binding protein. Elife, 9, 2020
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5N4W
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![BU of 5n4w by Molmil](/molmil-images/mine/5n4w) | Crystal structure of the Cul2-Rbx1-EloBC-VHL ubiquitin ligase complex | 分子名称: | Cullin-2, E3 ubiquitin-protein ligase RBX1, Elongin-B, ... | 著者 | Cardote, T.A.F, Gadd, M.S, Ciulli, A. | 登録日 | 2017-02-11 | 公開日 | 2017-06-07 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | 主引用文献 | Crystal Structure of the Cul2-Rbx1-EloBC-VHL Ubiquitin Ligase Complex. Structure, 25, 2017
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6UXO
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![BU of 6uxo by Molmil](/molmil-images/mine/6uxo) | Crystal structure of BAK core domain BH3-groove-dimer in complex with DDM | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Bcl-2 homologous antagonist/killer, ... | 著者 | Cowan, A.D, Colman, P.M, Czabotar, P.E. | 登録日 | 2019-11-07 | 公開日 | 2020-09-02 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.799 Å) | 主引用文献 | BAK core dimers bind lipids and can be bridged by them. Nat.Struct.Mol.Biol., 27, 2020
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6MVQ
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![BU of 6mvq by Molmil](/molmil-images/mine/6mvq) | HCV NS5B 1b N316 bound to Compound 31 | 分子名称: | (4-{1-[5-cyclopropyl-2-(4-fluorophenyl)-3-(methylcarbamoyl)-1-benzofuran-6-yl]-1H-1,2,4-triazol-5-yl}-2-fluorophenyl)boronic acid, HCV Polymerase | 著者 | Williams, S.P, Kahler, K, Price, D.J, Peat, A.J. | 登録日 | 2018-10-26 | 公開日 | 2019-09-04 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Design of N-Benzoxaborole Benzofuran GSK8175-Optimization of Human Pharmacokinetics Inspired by Metabolites of a Failed Clinical HCV Inhibitor. J.Med.Chem., 62, 2019
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4Z13
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![BU of 4z13 by Molmil](/molmil-images/mine/4z13) | Recombinantly expressed latent aurone synthase (polyphenol oxidase) co-crystallized with hexatungstotellurate(VI) and soaked in H2O2 | 分子名称: | 6-tungstotellurate(VI), Aurone synthase, COPPER (II) ION, ... | 著者 | Molitor, C, Mauracher, S.G, Rompel, A. | 登録日 | 2015-03-26 | 公開日 | 2016-03-23 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Aurone synthase is a catechol oxidase with hydroxylase activity and provides insights into the mechanism of plant polyphenol oxidases. Proc.Natl.Acad.Sci.USA, 113, 2016
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8RIH
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8QBF
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![BU of 8qbf by Molmil](/molmil-images/mine/8qbf) | Compact state - Pil1 dimer with lipid headgroups fitted in native eisosome lattice bound to plasma membrane microdomain | 分子名称: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, PHOSPHOSERINE, Sphingolipid long chain base-responsive protein PIL1 | 著者 | Kefauver, J.M, Zou, L, Desfosses, A, Loewith, R.J. | 登録日 | 2023-08-24 | 公開日 | 2024-07-24 | 最終更新日 | 2024-08-28 | 実験手法 | ELECTRON MICROSCOPY (3.67 Å) | 主引用文献 | Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain. Nature, 632, 2024
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5NAP
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![BU of 5nap by Molmil](/molmil-images/mine/5nap) | Torpedo californica acetylcholinesterase in complex with a non-chiral donepezil-like inhibitor 17 | 分子名称: | (2~{E})-5,6-dimethoxy-2-[[1-(phenylmethyl)piperidin-4-yl]methylidene]-3~{H}-inden-1-one, Acetylcholinesterase, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Caliandro, R, Pesaresi, A, Lamba, D. | 登録日 | 2017-02-28 | 公開日 | 2018-05-02 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Kinetic and structural studies on the interactions of Torpedo californica acetylcholinesterase with two donepezil-like rigid analogues. J Enzyme Inhib Med Chem, 33, 2018
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6WDD
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![BU of 6wdd by Molmil](/molmil-images/mine/6wdd) | Cryo-EM of elongating ribosome with EF-Tu*GTP elucidates tRNA proofreading (Cognate Structure V-A) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Loveland, A.B, Demo, G, Korostelev, A.A. | 登録日 | 2020-03-31 | 公開日 | 2020-07-01 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Cryo-EM of elongating ribosome with EF-Tu•GTP elucidates tRNA proofreading. Nature, 584, 2020
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6TAV
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![BU of 6tav by Molmil](/molmil-images/mine/6tav) | Crystal structure of endopeptidase-induced alpha2-macroglobulin | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-2-macroglobulin, ... | 著者 | Gomis-Ruth, F.X, Duquerroy, S, Trapani, S, Marrero, A, Goulas, T, Guevara, T, Andersen, G.A, Sottrup-Jensen, L, Navaza, J. | 登録日 | 2019-10-30 | 公開日 | 2021-05-12 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | 主引用文献 | Cryo-EM structures shows the mechanistic basis of pan-peptidase inhibition by human alpha2-macroglobulin Proc.Natl.Acad.Sci.USA, 2022
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6QO0
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