5UM8
| Crystal structure of HIV-1 envelope trimer 16055 NFL TD CC (T569G) in complex with Fabs 35022 and PGT124 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 35022 heavy chain, ... | 著者 | Garces, F, Stanfield, R.L, Wilson, I.A. | 登録日 | 2017-01-26 | 公開日 | 2017-05-24 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.935 Å) | 主引用文献 | Glycine Substitution at Helix-to-Coil Transitions Facilitates the Structural Determination of a Stabilized Subtype C HIV Envelope Glycoprotein. Immunity, 46, 2017
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8V7O
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6STF
| Human Rab8a phosphorylated at Ser111 in complex with GDP | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-8A | 著者 | Vieweg, S, Mulholland, K, Braeuning, B, Kachariya, N, Lai, Y, Toth, R, Sattler, M, Groll, M, Itzen, A, Muqit, M.M.K. | 登録日 | 2019-09-10 | 公開日 | 2020-04-22 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | PINK1-dependent phosphorylation of Serine111 within the SF3 motif of Rab GTPases impairs effector interactions and LRRK2-mediated phosphorylation at Threonine72. Biochem.J., 477, 2020
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4NXM
| Crystal Structure of the 30S ribosomal subunit from a GidB (RsmG) mutant of Thermus thermophilus (HB8) | 分子名称: | 16S rRNA, MAGNESIUM ION, ZINC ION, ... | 著者 | Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G. | 登録日 | 2013-12-09 | 公開日 | 2014-05-21 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (3.65 Å) | 主引用文献 | A structural basis for streptomycin resistance To be Published
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4Z2G
| Serratia marcescens Chitinase B complexed with macrolide inhibitor 26 | 分子名称: | (1R,2R,3R,6R,7S,8S,9R,10R,12R,13S,17S)-3-ethyl-2,10-dihydroxy-2,6,8,10,12,15,15,17-octamethyl-5-oxo-9-(prop-2-yn-1-yloxy)-4,14,16-trioxabicyclo[11.3.1]heptadec-7-yl {4-[N'-(methylcarbamoyl)carbamimidamido]butyl}carbamate, Chitinase B | 著者 | Maita, N, Sugawara, A, Sunazuka, T. | 登録日 | 2015-03-30 | 公開日 | 2015-07-01 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Creation of Customized Bioactivity within a 14-Membered Macrolide Scaffold: Design, Synthesis, and Biological Evaluation Using a Family-18 Chitinase J.Med.Chem., 58, 2015
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7QS8
| Structural insight into the Scribble PDZ domains interaction with the oncogenic Human T-cell lymphotrophic virus-1 (HTLV-1) Tax1 | 分子名称: | Protein Tax-1, Protein scribble homolog | 著者 | Javorsky, A, Soares da Costa, T.P, Mackie, E.R, Humbert, P.O, Kvansakul, M. | 登録日 | 2022-01-13 | 公開日 | 2022-09-07 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural insight into the Scribble PDZ domains interaction with the oncogenic Human T-cell lymphotrophic virus-1 (HTLV-1) Tax1 PBM. Febs J., 290, 2023
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5Y4A
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8B7X
| X-ray structure of the CeuE Homologue from Geobacillus stearothermophilus - apo form. | 分子名称: | O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500), SULFATE ION, Siderophore ABC transporter substrate-binding protein | 著者 | Wilson, K.S, Duhme-Klair, A.K, Blagova, E.V, Bennett, M. | 登録日 | 2022-10-03 | 公開日 | 2023-07-12 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | Thermostable homologues of the periplasmic siderophore-binding protein CeuE from Geobacillus stearothermophilus and Parageobacillus thermoglucosidasius. Acta Crystallogr D Struct Biol, 79, 2023
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8OIG
| Crystal Structure of Staphopain C from Staphylococcus aureus | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... | 著者 | McEwen, A.G, Magoch, M, Napolitano, V, Dubin, G, Wladyka, B. | 登録日 | 2023-03-22 | 公開日 | 2023-06-21 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Crystal Structure of Staphopain C from Staphylococcus aureus. Molecules, 28, 2023
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5HAW
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8FAC
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5HBB
| Crystal structure of shaft pilin spaA from Lactobacillus rhamnosus GG - E139A mutant | 分子名称: | 1,2-ETHANEDIOL, Cell surface protein SpaA, SODIUM ION, ... | 著者 | Chaurasia, P, Pratap, S, von Ossowski, I, Palva, A, Krishnan, V. | 登録日 | 2015-12-31 | 公開日 | 2016-07-20 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | 主引用文献 | New insights about pilus formation in gut-adapted Lactobacillus rhamnosus GG from the crystal structure of the SpaA backbone-pilin subunit Sci Rep, 6, 2016
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8OUY
| Human RAD51B-RAD51C-RAD51D-XRCC2 (BCDX2) complex, 3.4 A resolution | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA repair protein RAD51 homolog 2, ... | 著者 | Greenhough, L.A, Liang, C.C, West, S.C. | 登録日 | 2023-04-25 | 公開日 | 2023-06-21 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structure and function of the RAD51B-RAD51C-RAD51D-XRCC2 tumour suppressor. Nature, 619, 2023
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4Z31
| Crystal structure of the RC3H2 ROQ domain in complex with stem-loop and double-stranded forms of RNA | 分子名称: | CHLORIDE ION, RNA (5'-R(*A)-D(P*UP*GP*UP*UP*CP*UP*GP*UP*GP*AP*AP*CP*AP*C)-3'), Roquin-2, ... | 著者 | DONG, A, ZHANG, Q, TEMPEL, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, TONG, Y, Structural Genomics Consortium (SGC) | 登録日 | 2015-03-30 | 公開日 | 2015-10-14 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | New Insights into the RNA-Binding and E3 Ubiquitin Ligase Activities of Roquins. Sci Rep, 5, 2015
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5IO0
| Xanthomonas campestris Peroxiredoxin Q - Structure F9 | 分子名称: | Bacterioferritin comigratory protein, SODIUM ION | 著者 | Perkins, A, Parsonage, D, Nelson, K.J, Poole, L.B, Karplus, A. | 登録日 | 2016-03-08 | 公開日 | 2016-09-21 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Peroxiredoxin Catalysis at Atomic Resolution. Structure, 24, 2016
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6H47
| Human KRAS in complex with darpin K19 | 分子名称: | GTPase KRas, SULFATE ION, darpin K19 | 著者 | Debreczeni, J.E, Bery, N, Legg, S, Breed, J, Embrey, K, Stubbs, C, Kolasinska-Zwierz, P, Barrett, N, Marwood, R, Watson, J, Tart, J, Overman, R, Miller, A, Phillips, C, Minter, R, Rabbitts, T.H. | 登録日 | 2018-07-20 | 公開日 | 2019-04-24 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | KRAS-specific inhibition using a DARPin binding to a site in the allosteric lobe. Nat Commun, 10, 2019
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8OYG
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5HDI
| Structural characterization of CYP144A1, a Mycobacterium tuberculosis cytochrome P450 | 分子名称: | Cytochrome P450 144, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Chenge, J, Driscoll, M.D, McLean, K.J, Munro, A.W, Leys, D. | 登録日 | 2016-01-05 | 公開日 | 2016-05-04 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Structural characterization of CYP144A1 - a cytochrome P450 enzyme expressed from alternative transcripts in Mycobacterium tuberculosis. Sci Rep, 6, 2016
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6W3U
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5IOW
| Xanthomonas campestris Peroxiredoxin Q - Structure FFcumene (Hyperoxidized by cumene hydroperoxide) | 分子名称: | Bacterioferritin comigratory protein, SODIUM ION | 著者 | Perkins, A, Parsonage, D, Nelson, K.J, Poole, L.B, Karplus, A. | 登録日 | 2016-03-09 | 公開日 | 2016-09-21 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Peroxiredoxin Catalysis at Atomic Resolution. Structure, 24, 2016
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8OYF
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8B4C
| ToxR bacterial transcriptional regulator bound to 20 bp toxT promoter DNA | 分子名称: | Cholera toxin transcriptional activator, DNA (20-MER) | 著者 | Canals, A, Pieretti, S, Muriel, M, El Yaman, N, Fabrega-Ferrer, M, Perez-Luque, R, Krukonis, E.S, Coll, M. | 登録日 | 2022-09-20 | 公開日 | 2023-08-09 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | ToxR activates the Vibrio cholerae virulence genes by tethering DNA to the membrane through versatile binding to multiple sites. Proc.Natl.Acad.Sci.USA, 120, 2023
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5ISQ
| Staphylococcus aureus H30N, F98Y Dihydrofolate Reductase mutant complexed with beta-NADPH and 3'-(3-(2,4-diamino-6-ethylpyrimidin-5-yl)prop-2-yn-1-yl)-4'-methoxy-[1,1'-biphenyl]-4-carboxylic acid (UCP1106) | 分子名称: | 4-[3-[3-[2,4-bis(azanyl)-6-ethyl-pyrimidin-5-yl]prop-2-ynyl]-4-methoxy-phenyl]benzoic acid, Dihydrofolate reductase, GLYCEROL, ... | 著者 | Anderson, A.C, Reeve, S.M. | 登録日 | 2016-03-15 | 公開日 | 2017-06-28 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Charged Propargyl-Linked Antifolates Reveal Mechanisms of Antifolate Resistance and Inhibit Trimethoprim-Resistant MRSA Strains Possessing Clinically Relevant Mutations. J. Med. Chem., 59, 2016
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5HRQ
| Insulin with proline analog HzP at position B28 in the R6 state | 分子名称: | CHLORIDE ION, Insulin A-Chain, Insulin B-Chain, ... | 著者 | Lieblich, S.A, Fang, K.Y, Cahn, J.K.B, Tirrell, D.A. | 登録日 | 2016-01-24 | 公開日 | 2017-01-25 | 最終更新日 | 2020-01-15 | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | 主引用文献 | 4S-Hydroxylation of Insulin at ProB28 Accelerates Hexamer Dissociation and Delays Fibrillation. J. Am. Chem. Soc., 139, 2017
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5HED
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