4Z31

Crystal structure of the RC3H2 ROQ domain in complex with stem-loop and double-stranded forms of RNA

Summary for 4Z31

• Entry DOI: 10.2210/pdb4z31/pdb
• Descriptor: Roquin-2, RNA (5'-R(*A)-D(P*UP*GP*UP*UP*CP*UP*GP*UP*GP*AP*AP*CP*AP*C)-3'), UNKNOWN ATOM OR ION, ... (5 entities in total)
• Functional Keywords: roquin2, rna, structural genomics, structural genomics consortium, sgc, rna binding protein-rna complex, rna binding protein/rna
• Biological source: Homo sapiens (Human); More
• Cellular location: Cytoplasm, P-body : Q9HBD1
• Total number of polymer chains: 6
• Total formula weight: 90596.97

Authors

DONG, A.,ZHANG, Q.,TEMPEL, W.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,TONG, Y.,Structural Genomics Consortium (SGC) (deposition date: 2015-03-30, release date: 2015-10-14, Last modification date: 2023-09-27)

• Primary citation: Zhang, Q.,Fan, L.,Hou, F.,Dong, A.,Wang, Y.X.,Tong, Y.; New Insights into the RNA-Binding and E3 Ubiquitin Ligase Activities of Roquins.; Sci Rep, 5:15660-15660, 2015; PubMed: 26489670; DOI: 10.1038/srep15660

Experimental method

X-RAY DIFFRACTION (2.5 Å)