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4Z31

Crystal structure of the RC3H2 ROQ domain in complex with stem-loop and double-stranded forms of RNA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Roquin-2polymer31935773.02UniProt (Q9HBD1)
Pfam (PF21206)
Pfam (PF18386)
Homo sapiens (Human)Membrane-associated nucleic acid-binding protein,RING finger and CCCH-type zinc finger domain-containing protein 2,RING finger protein 164
2C, D, E, F
(C, D, E, F)
RNA (5'-R(*A)-D(P*UP*GP*UP*UP*CP*UP*GP*UP*GP*AP*AP*CP*AP*C)-3')polymer154753.94Homo sapiens
3G, H
(A)
UNKNOWN ATOM OR IONnon-polymer2Chemie (UNX)
4I
(B)
CHLORIDE IONnon-polymer35.51Chemie (CL)
5J, K, L, M, N
(A, B, D, E, F)
waterwater18.040Chemie (HOH)
Sequence modifications
A, B: 87 - 404 (UniProt: Q9HBD1)
PDBExternal DatabaseDetails
Gly 86-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight90561.5
Non-Polymers*Number of molecules3
Total formula weight35.5
All*Total formula weight90597.0
*Water molecules are not included.

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PDB entries from 2025-06-11

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