5LYK
 
 | | CRYSTAL STRUCTURE OF INTRACELLULAR B30.2 DOMAIN OF BTN3A1 BOUND TO CITRATE | | 分子名称: | 1,2-ETHANEDIOL, Butyrophilin subfamily 3 member A1, CITRATE ANION | | 著者 | Mohammed, F, Baker, A.T, Salim, M, Willcox, B.E. | | 登録日 | 2016-09-28 | | 公開日 | 2017-09-13 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | BTN3A1 Discriminates gamma delta T Cell Phosphoantigens from Nonantigenic Small Molecules via a Conformational Sensor in Its B30.2 Domain.
ACS Chem. Biol., 12, 2017
|
|
7B0C
 | | [4Fe-4S]-NsrR complexed to 23-bp HmpA1 operator fragment | | 分子名称: | DNA (5'-D(P*AP*AP*CP*AP*CP*GP*AP*AP*TP*AP*TP*CP*AP*TP*CP*TP*AP*CP*CP*AP*AP*TP*T)-3'), DNA (5'-D(P*AP*AP*TP*TP*GP*GP*TP*AP*GP*AP*TP*GP*AP*TP*AP*TP*TP*CP*GP*TP*GP*TP*T)-3'), HTH-type transcriptional repressor NsrR, ... | | 著者 | Rohac, R, Fontecilla-Camps, J.C, Volbeda, A. | | 登録日 | 2020-11-19 | | 公開日 | 2022-06-01 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural determinants of DNA recognition by the NO sensor NsrR and related Rrf2-type [FeS]-transcription factors.
Commun Biol, 5, 2022
|
|
6PQF
 | |
1UVU
 | | BOVINE THROMBIN--BM12.1700 COMPLEX | | 分子名称: | 3-(7-DIAMINOMETHYL-NAPHTHALEN-2-YL)-PROPIONIC ACID ETHYL ESTER, THROMBIN | | 著者 | Engh, R.A, Huber, R. | | 登録日 | 1996-10-16 | | 公開日 | 1997-11-19 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Enzyme flexibility, solvent and 'weak' interactions characterize thrombin-ligand interactions: implications for drug design.
Structure, 4, 1996
|
|
8BZO
 | | Cryo-EM structure of CDK2-CyclinA in complex with p27 from the SCFSKP2 E3 ligase Complex | | 分子名称: | Cyclin-A2, Cyclin-dependent kinase 2, Cyclin-dependent kinase inhibitor 1B | | 著者 | Rowland, R.J, Salamina, M, Endicott, J.A, Noble, M.E. | | 登録日 | 2022-12-15 | | 公開日 | 2023-06-28 | | 最終更新日 | 2023-07-19 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Cryo-EM structure of SKP1-SKP2-CKS1 in complex with CDK2-cyclin A-p27KIP1.
Sci Rep, 13, 2023
|
|
5KKR
 | | KSR2:MEK1 Complex Bound to the Small Molecule APS-2-79 | | 分子名称: | 6,7-dimethoxy-~{N}-(2-methyl-4-phenoxy-phenyl)quinazolin-4-amine, Dual specificity mitogen-activated protein kinase kinase 1, Kinase suppressor of Ras 2 | | 著者 | Dhawan, N.S, Scopton, A.P, Dar, A.C. | | 登録日 | 2016-06-22 | | 公開日 | 2016-08-31 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.509 Å) | | 主引用文献 | Small molecule stabilization of the KSR inactive state antagonizes oncogenic Ras signalling.
Nature, 537, 2016
|
|
5E1F
 | | Crystal structure of Staphylococcal nuclease variant Delta+PHS G20E at cryogenic temperature | | 分子名称: | CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease | | 著者 | Skerritt, L.A, Bell-Upp, P.C, Siegler, M.A, Schlessman, J.L, Garcia-Moreno E, B. | | 登録日 | 2015-09-29 | | 公開日 | 2015-10-14 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of Staphylococcal nuclease variant Delta+PHS G20E at cryogenic temperature
To be Published
|
|
6U10
 | | Crystal Structure of the metallo-beta-lactamase L1 from Stenotrophomonas maltophilia in the complex with the inhibitor captopril | | 分子名称: | 1,2-ETHANEDIOL, FORMIC ACID, L-CAPTOPRIL, ... | | 著者 | Kim, Y, Maltseva, N, Endres, M, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2019-08-15 | | 公開日 | 2019-09-11 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Crystal Structure of the metallo-beta-lactamase L1 from Stenotrophomonas maltophilia in the complex with the inhibitor captopril.
To Be Published
|
|
6RMC
 | | Crystal structure of the DEAH-box ATPase Prp2 in complex with Spp2 and ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Putative mRNA splicing factor, ... | | 著者 | Hamann, F, Neumann, P, Schmitt, A, Ficner, R. | | 登録日 | 2019-05-06 | | 公開日 | 2020-02-05 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6ROJ
 | | Cryo-EM structure of the activated Drs2p-Cdc50p | | 分子名称: | (2R)-1-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cell division control protein 50, ... | | 著者 | Timcenko, M, Lyons, J.A, Januliene, D, Ulstrup, J.J, Dieudonne, T, Montigny, C, Ash, M.R, Karlsen, J.L, Boesen, T, Kuhlbrandt, W, Lenoir, G, Moeller, A, Nissen, P. | | 登録日 | 2019-05-13 | | 公開日 | 2019-07-03 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structure and autoregulation of a P4-ATPase lipid flippase.
Nature, 571, 2019
|
|
5LWH
 | | CeuE (Y288F variant) a periplasmic protein from Campylobacter jejuni. | | 分子名称: | Enterochelin ABC transporter substrate-binding protein, ZINC ION | | 著者 | Wilde, E.J, Blagova, E, Hughes, A, Raines, D.J, Moroz, O.V, Turkenburg, J, Duhme-Klair, A.-K, Wilson, K.S. | | 登録日 | 2016-09-16 | | 公開日 | 2017-04-12 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | | 主引用文献 | Interactions of the periplasmic binding protein CeuE with Fe(III) n-LICAM(4-) siderophore analogues of varied linker length.
Sci Rep, 7, 2017
|
|
3RPE
 | | 1.1 Angstrom Crystal Structure of Putative Modulator of Drug Activity (MdaB) from Yersinia pestis CO92. | | 分子名称: | DI(HYDROXYETHYL)ETHER, FLAVIN-ADENINE DINUCLEOTIDE, Modulator of drug activity B | | 著者 | Minasov, G, Halavaty, A, Shuvalova, L, Dubrovska, I, Winsor, J, Papazisi, L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2011-04-26 | | 公開日 | 2011-05-04 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | 1.1 Angstrom Crystal Structure of Putative Modulator of Drug Activity (MdaB) from Yersinia pestis CO92.
TO BE PUBLISHED
|
|
8BYA
 | | Cryo-EM structure of SKP1-SKP2-CKS1-CDK2-CyclinA-p27KIP1 Complex | | 分子名称: | Cyclin-A2, Cyclin-dependent kinase 2, Cyclin-dependent kinase inhibitor 1B, ... | | 著者 | Rowland, R.J, Salamina, M, Endicott, J.A, Noble, M.E. | | 登録日 | 2022-12-12 | | 公開日 | 2023-06-28 | | 最終更新日 | 2023-07-19 | | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | | 主引用文献 | Cryo-EM structure of SKP1-SKP2-CKS1 in complex with CDK2-cyclin A-p27KIP1.
Sci Rep, 13, 2023
|
|
5WSY
 | | The complex structure of SAV606 with N-carboxymethyl-3-aminobutyrate | | 分子名称: | (3~{R})-3-(2-hydroxy-2-oxoethylamino)butanoic acid, Uncharacterized protein | | 著者 | Chisuga, T, Miyanaga, A, Kudo, F, Eguchi, T. | | 登録日 | 2016-12-08 | | 公開日 | 2017-05-31 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural analysis of the dual-function thioesterase SAV606 unravels the mechanism of Michael addition of glycine to an alpha , beta-unsaturated thioester.
J. Biol. Chem., 292, 2017
|
|
3PF5
 | |
6HBC
 | | Structure of the repeat unit in the network formed by CcmM and Rubisco from Synechococcus elongatus | | 分子名称: | Carbon dioxide concentrating mechanism protein CcmM, Ribulose 1,5-bisphosphate carboxylase small subunit, Ribulose bisphosphate carboxylase large chain | | 著者 | Wang, H, Yan, X, Aigner, H, Bracher, A, Nguyen, N.D, Hee, W.Y, Long, B.M, Price, G.D, Hartl, F.U, Hayer-Hartl, M. | | 登録日 | 2018-08-10 | | 公開日 | 2018-12-12 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (2.78 Å) | | 主引用文献 | Rubisco condensate formation by CcmM in beta-carboxysome biogenesis.
Nature, 566, 2019
|
|
6U05
 | | Crystal Structure of Fungal RNA Kinase | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | | 著者 | Shuman, S, Goldgur, Y, Banerjee, A. | | 登録日 | 2019-08-13 | | 公開日 | 2019-11-06 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.948 Å) | | 主引用文献 | Atomic structures of the RNA end-healing 5'-OH kinase and 2',3'-cyclic phosphodiesterase domains of fungal tRNA ligase: conformational switches in the kinase upon binding of the GTP phosphate donor.
Nucleic Acids Res., 47, 2019
|
|
8KB2
 | | Crystal Structure of M- and C-Domains of the shaft pilin LrpA from Ligilactobacillus ruminis - iodide derivative | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... | | 著者 | Prajapati, A, Palva, A, von Ossowski, I, Krishnan, V. | | 登録日 | 2023-08-03 | | 公開日 | 2024-07-10 | | 最終更新日 | 2024-07-17 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | The crystal structure of the N-terminal domain of the backbone pilin LrpA reveals a new closure-and-twist motion for assembling dynamic pili in Ligilactobacillus ruminis.
Acta Crystallogr D Struct Biol, 80, 2024
|
|
8UKC
 | | Solution NMR Structure of the lasso peptide chlorolassin | | 分子名称: | Lassopeptide Chlorolassin | | 著者 | Saad, H, Zhu, L, Harris, L.A, Shelton, K.E, Mitchell, D.A. | | 登録日 | 2023-10-12 | | 公開日 | 2024-09-25 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Tryptophan-Centric Bioinformatics Identifies New Lasso Peptide Modifications.
Biochemistry, 63, 2024
|
|
6RRT
 | | T=4 MS2 Virus-like-particle | | 分子名称: | Capsid protein | | 著者 | de Martin Garrido, N, Ramlaul, K, Simpson, P.A, Crone, M.A, Freemont, P.S, Aylett, C.H.S. | | 登録日 | 2019-05-20 | | 公開日 | 2020-07-08 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (6 Å) | | 主引用文献 | Bacteriophage MS2 displays unreported capsid variability assembling T = 4 and mixed capsids.
Mol.Microbiol., 113, 2020
|
|
1T90
 | | Crystal structure of methylmalonate semialdehyde dehydrogenase from Bacillus subtilis | | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Probable methylmalonate-semialdehyde dehydrogenase | | 著者 | Dubourg, H, Didierjean, C, Stines-Chaumeil, C, Talfournier, F, Branlant, G, Aubry, A, Corbier, C. | | 登録日 | 2004-05-14 | | 公開日 | 2006-01-03 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure analysis of Methylmalonate-Semialdehyde Dehydrogenase from Bacillus subtilis.
To be published
|
|
7AFR
 | | Ribosome maturation factor RimP (apo) | | 分子名称: | Ribosome maturation factor RimP | | 著者 | Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Fucini, P, Connell, S. | | 登録日 | 2020-09-19 | | 公開日 | 2021-07-07 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit.
Sci Adv, 7, 2021
|
|
8UKG
 | | Solution NMR structure of the lasso peptide wygwalassin-A1 | | 分子名称: | Lassopeptide wygwalassin-A1 | | 著者 | Saad, H, Zhu, L, Harris, L.A, Shelton, K.E, Mitchell, D.A. | | 登録日 | 2023-10-13 | | 公開日 | 2024-09-25 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Tryptophan-Centric Bioinformatics Identifies New Lasso Peptide Modifications.
Biochemistry, 63, 2024
|
|
6PYR
 | | Human PI3Kdelta in complex with Compound 2-10 ((3S)-3-benzyl-3-methyl-5-[5-(2-methylpyrimidin-5-yl)pyrazolo[1,5-a]pyrimidin-3-yl]-1,3-dihydro-2H-indol-2-one) | | 分子名称: | (3S)-3-benzyl-3-methyl-5-[5-(2-methylpyrimidin-5-yl)pyrazolo[1,5-a]pyrimidin-3-yl]-1,3-dihydro-2H-indol-2-one, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | | 著者 | Lesburg, C.A, Augustin, M.A. | | 登録日 | 2019-07-30 | | 公開日 | 2019-08-28 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Design of selective PI3K delta inhibitors using an iterative scaffold-hopping workflow.
Bioorg.Med.Chem.Lett., 29, 2019
|
|
6YNX
 | | Cryo-EM structure of Tetrahymena thermophila mitochondrial ATP synthase - Fo-subcomplex | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, ADENOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Kock Flygaard, R, Muhleip, A, Amunts, A. | | 登録日 | 2020-04-14 | | 公開日 | 2020-09-30 | | 最終更新日 | 2020-11-11 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Type III ATP synthase is a symmetry-deviated dimer that induces membrane curvature through tetramerization.
Nat Commun, 11, 2020
|
|
