6WIN
 
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4RKR
 | | Crystal structure of LacI family transcriptional regulator from Arthrobacter sp. FB24, target EFI-560007, complex with lactose | | 分子名称: | Transcriptional regulator, LacI family, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose | | 著者 | Patskovsky, Y, Toro, R, Bhosle, R, Al Obaidi, N, Chamala, S, Attonito, J.D, Scott Glenn, A, Chowdhury, S, Lafleur, J, Siedel, R.D, Hillerich, B, Love, J, Whalen, K.L, Gerlt, J.A, Burley, S.K, Almo, S.C, Enzyme Function Initiative (EFI) | | 登録日 | 2014-10-13 | | 公開日 | 2014-11-12 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal Structure of LacI Transcriptional Regulator PurR from Arthrobacter Sp, Target Nysgxrc 11027R
To be Published
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6FNQ
 | | Ergothioneine-biosynthetic methyltransferase EgtD in complex with N,N,N-trimethylhistidine (hercynine) | | 分子名称: | GLYCEROL, Histidine N-alpha-methyltransferase, MAGNESIUM ION, ... | | 著者 | Vit, A, Blankenfeldt, W, Seebeck, F.P. | | 登録日 | 2018-02-05 | | 公開日 | 2018-06-13 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Inhibition and Regulation of the Ergothioneine Biosynthetic Methyltransferase EgtD.
ACS Chem. Biol., 13, 2018
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4Z74
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8HH8
 | | F1 domain of FoF1-ATPase from Bacillus PS3,post-hyd,lowATP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase gamma chain, ... | | 著者 | Nakano, A, Kishikawa, J, Mitsuoka, K, Yokoyama, K. | | 登録日 | 2022-11-16 | | 公開日 | 2023-07-26 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Rotation mechanism of ATP synthases driven by ATP hydrolysis
To Be Published
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7K5F
 | | 1.90 A resolution structure of WT BfrB from Pseudomonas aeruginosa in complex with a protein-protein interaction inhibitor KM-5-50 | | 分子名称: | 4-{[(3-chloro-5-hydroxyphenyl)methyl]amino}-1H-isoindole-1,3(2H)-dione, Ferroxidase, POTASSIUM ION, ... | | 著者 | Lovell, S, Battaile, K.P, Soldano, A, Punchi-Hewage, A, Meraz, K, Annor-Gyamfi, J.K, Yao, H, Bunce, R.A, Rivera, M. | | 登録日 | 2020-09-16 | | 公開日 | 2020-12-16 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Small Molecule Inhibitors of the Bacterioferritin (BfrB)-Ferredoxin (Bfd) Complex Kill Biofilm-Embedded Pseudomonas aeruginosa Cells.
Acs Infect Dis., 7, 2021
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5LRL
 | | CRYSTAL STRUCTURE OF HSP90 IN COMPLEX WITH A003492875 | | 分子名称: | 2-azanyl-5-chloranyl-~{N}-[(9~{R})-4-(1~{H}-imidazo[4,5-c]pyridin-2-yl)-9~{H}-fluoren-9-yl]pyrimidine-4-carboxamide, Heat shock protein HSP 90-alpha | | 著者 | Vallee, F, Dupuy, A. | | 登録日 | 2016-08-19 | | 公開日 | 2017-08-23 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.33 Å) | | 主引用文献 | Estimation of Protein-Ligand Unbinding Kinetics Using Non-Equilibrium Targeted Molecular Dynamics Simulations.
J.Chem.Inf.Model., 59, 2019
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5H88
 | | Crystal structure of mRojoA mutant - T16V -P63F - W143A - L163V | | 分子名称: | mRojoA fluorescent protein | | 著者 | Pandelieva, A.T, Tremblay, V, Sarvan, S, Chica, R.A, Couture, J.-F. | | 登録日 | 2015-12-23 | | 公開日 | 2016-01-27 | | 最終更新日 | 2016-03-02 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | Brighter Red Fluorescent Proteins by Rational Design of Triple-Decker Motif.
Acs Chem.Biol., 11, 2016
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6B7W
 | | Structure of hen egg-white lysozyme pre-treated with high pressure (600 MPa) under isobaric condition | | 分子名称: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | | 著者 | Morais, M.A.B, Nascimento, A.F.Z, Tominaga, C.Y, Cristianini, M, Tribst, A.A.L, Murakami, M.T. | | 登録日 | 2017-10-05 | | 公開日 | 2018-07-25 | | 実験手法 | X-RAY DIFFRACTION (1.482 Å) | | 主引用文献 | How high pressure pre-treatments affect the function and structure of hen egg-white lysozyme
Innov Food Sci Emerg Technol, 47, 2018
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6FOF
 | | Crystal structure of a crystallized variant of h-Gal3: Gal-3[NTS/VII-IX] | | 分子名称: | Galectin-3,Galectin-3, SULFATE ION, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | | 著者 | Romero, A, Flores-Ibarra, A, Medrano, F.J. | | 登録日 | 2018-02-07 | | 公開日 | 2018-07-18 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystallization of a human galectin-3 variant with two ordered segments in the shortened N-terminal tail.
Sci Rep, 8, 2018
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5K3O
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7R15
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4Z8A
 | | SH3-III of Drosophila Rim-binding protein bound to a Cacophony derived peptide | | 分子名称: | RIM-binding protein, isoform F, Voltage-dependent calcium channel type A subunit alpha-1 | | 著者 | Driller, J.H, Holton, N, Siebert, M, Boehme, A.M, Wahl, M.C, Sigrist, S.J, Loll, B. | | 登録日 | 2015-04-08 | | 公開日 | 2015-08-05 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.759 Å) | | 主引用文献 | A high affinity RIM-binding protein/Aplip1 interaction prevents the formation of ectopic axonal active zones.
Elife, 4, 2015
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5K45
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4Z2U
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5JP0
 | | Bacteroides ovatus Xyloglucan PUL GH3B with bound glucose | | 分子名称: | Beta-glucosidase BoGH3B, MAGNESIUM ION, beta-D-glucopyranose | | 著者 | Hemsworth, G.R, Thompson, A.J, Stepper, J, Sobala, L.F, Coyle, T, Larsbrink, J, Spadiut, O, Stubbs, K.A, Brumer, H, Davies, G.J. | | 登録日 | 2016-05-03 | | 公開日 | 2016-08-10 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural dissection of a complex Bacteroides ovatus gene locus conferring xyloglucan metabolism in the human gut.
Open Biology, 6, 2016
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7R10
 | | Dissociated S1 domain of Alpha Variant SARS-CoV-2 Spike bound to ACE2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike glycoprotein, ... | | 著者 | Benton, D.J, Wrobel, A.G, Gamblin, S.J. | | 登録日 | 2022-02-02 | | 公開日 | 2022-03-02 | | 最終更新日 | 2022-03-16 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Evolution of the SARS-CoV-2 spike protein in the human host.
Nat Commun, 13, 2022
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6BZ4
 | | Human IgG1 lacking complement-dependent cytotoxicity: hu3S193 Fc mutant K322A | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Farrugia, W, Burvenich, I.G.J, Scott, A.M, Ramsland, P.A. | | 登録日 | 2017-12-22 | | 公開日 | 2018-06-13 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Global conformational changes in IgG-Fc upon mutation of the FcRn-binding site are not associated with altered antibody-dependent effector functions.
Biochem. J., 475, 2018
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6QW4
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5HGK
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5T77
 | | Crystal structure of the MOP flippase MurJ | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CALCIUM ION, ... | | 著者 | Kuk, A.C.Y, Lee, S.-Y. | | 登録日 | 2016-09-02 | | 公開日 | 2016-12-28 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of the MOP flippase MurJ in an inward-facing conformation.
Nat. Struct. Mol. Biol., 24, 2017
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5HBH
 | | CDK8-CYCC IN COMPLEX WITH 5-{5-Chloro-4-[1-(2-methoxy-ethyl)-1,8-diaza-spiro[4.5]dec-8-yl]-pyridin-3-yl}-1-methyl-1,3-dihydro-benzo[c]isothiazole 2,2-dioxide | | 分子名称: | 1,2-ETHANEDIOL, 5-[5-chloranyl-4-[1-(2-methoxyethyl)-1,8-diazaspiro[4.5]decan-8-yl]pyridin-3-yl]-1-methyl-3~{H}-2,1-benzothiazole 2,2-dioxide, Cyclin-C, ... | | 著者 | Musil, D, Blagg, J, Mallinger, A. | | 登録日 | 2015-12-31 | | 公開日 | 2016-02-03 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Discovery of Potent, Selective, and Orally Bioavailable Small-Molecule Modulators of the Mediator Complex-Associated Kinases CDK8 and CDK19.
J.Med.Chem., 59, 2016
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4RVX
 | | Crystal structure of multidrug-resistant clinical isolate A02 HIV-1 protease in complex with non-peptidic inhibitor, GRL079 | | 分子名称: | (4S)-4-amino-N-[(2S,3S)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]-3,4-dihydro-2H-chromene-6-carboxamide, HIV-1 Protease | | 著者 | Yedidi, R.S, Garimella, H, Kaufman, J.D, Das, D, Wingfield, P.T, Ghosh, A.K, Mitsuya, H. | | 登録日 | 2014-11-28 | | 公開日 | 2016-05-04 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.955 Å) | | 主引用文献 | Enhanced antiviral activity by the P2-tris-tetrahydrofuran moiety of GRL-0519, a novel nonpeptidic HIV-1 protease inhibitor (PI), against multi-PI-resistant and highly darunavir-resistant strains of HIV-1.
To be Published
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7JMG
 | | Functional Pathways of Biomolecules Retrieved from Single-particle Snapshots - Frame 22 - State 2 (S2) | | 分子名称: | CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ZINC ION, ... | | 著者 | Dashti, A, des Georges, A, Frank, J, Ourmazd, A. | | 登録日 | 2020-07-31 | | 公開日 | 2020-08-12 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Retrieving functional pathways of biomolecules from single-particle snapshots.
Nat Commun, 11, 2020
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8HH6
 | | F1 domain of FoF1-ATPase from Bacillus PS3,step waiting,highATP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase gamma chain, ... | | 著者 | Nakano, A, Kishikawa, J, Mitsuoka, K, Yokoyama, K. | | 登録日 | 2022-11-16 | | 公開日 | 2023-07-26 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Rotation mechanism of ATP synthases driven by ATP hydrolysis
To Be Published
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