4Z74

Crystal structure of inorganic pyrophosphatase from Mycobacterium tuberculosis in complex with inorganic pyrophosphate

Summary for 4Z74

Entry DOI	10.2210/pdb4z74/pdb
Related	4Z70 4Z71 4Z72 4Z73
Descriptor	Inorganic pyrophosphatase, PYROPHOSPHATE 2-, CALCIUM ION, ... (4 entities in total)
Functional Keywords	pyrophosphatase, phosphatase, hydrolase, inorganic pyrophosphate
Biological source	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Cellular location	Cytoplasm : P9WI55
Total number of polymer chains	12
Total formula weight	237333.34
Authors	Pratt, A.C.,Biswas, T.,Tsodikov, O.V. (deposition date: 2015-04-06, release date: 2015-08-26, Last modification date: 2024-03-06)
Primary citation	Pratt, A.C.,Dewage, S.W.,Pang, A.H.,Biswas, T.,Barnard-Britson, S.,Cisneros, G.A.,Tsodikov, O.V. Structural and computational dissection of the catalytic mechanism of the inorganic pyrophosphatase from Mycobacterium tuberculosis. J.Struct.Biol., 192:76-87, 2015 Cited by PubMed: 26296329 DOI: 10.1016/j.jsb.2015.08.010 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.55 Å)

Structure validation