5LRL
CRYSTAL STRUCTURE OF HSP90 IN COMPLEX WITH A003492875
Summary for 5LRL
Entry DOI | 10.2210/pdb5lrl/pdb |
Descriptor | Heat shock protein HSP 90-alpha, 2-azanyl-5-chloranyl-~{N}-[(9~{R})-4-(1~{H}-imidazo[4,5-c]pyridin-2-yl)-9~{H}-fluoren-9-yl]pyrimidine-4-carboxamide (3 entities in total) |
Functional Keywords | chaperone protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 23758.32 |
Authors | Vallee, F.,Dupuy, A. (deposition date: 2016-08-19, release date: 2017-08-23, Last modification date: 2024-01-10) |
Primary citation | Wolf, S.,Amaral, M.,Lowinski, M.,Vallee, F.,Musil, D.,Guldenhaupt, J.,Dreyer, M.K.,Bomke, J.,Frech, M.,Schlitter, J.,Gerwert, K. Estimation of Protein-Ligand Unbinding Kinetics Using Non-Equilibrium Targeted Molecular Dynamics Simulations. J.Chem.Inf.Model., 59:5135-5147, 2019 Cited by PubMed: 31697501DOI: 10.1021/acs.jcim.9b00592 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.33 Å) |
Structure validation
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