4RGO
| Structure of Staphylococcal Enterotoxin B bound to the neutralizing antibody 14G8 | Descriptor: | 14G8 heavy chain, 14G8 light chain, ACETATE ION, ... | Authors: | Franklin, M.C, Dutta, K, Varshney, A.K, Goger, M.J, Fries, B.C. | Deposit date: | 2014-09-30 | Release date: | 2015-01-21 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Mechanisms mediating enhanced neutralization efficacy of staphylococcal enterotoxin B by combinations of monoclonal antibodies. J.Biol.Chem., 290, 2015
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3LP9
| Crystal structure of LS24, A Seed Albumin from Lathyrus sativus | Descriptor: | CALCIUM ION, CHLORIDE ION, LS-24, ... | Authors: | Gaur, V, Qureshi, I.A, Singh, A, Chanana, V, Salunke, D.M. | Deposit date: | 2010-02-05 | Release date: | 2010-02-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure and functional insights of hemopexin fold protein from grass pea Plant Physiol., 152, 2010
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6B3E
| Crystal structure of human CDK12/CyclinK in complex with an inhibitor | Descriptor: | 1,2-ETHANEDIOL, 2-[(2S)-1-(6-{[(4,5-difluoro-1H-benzimidazol-2-yl)methyl]amino}-9-ethyl-9H-purin-2-yl)piperidin-2-yl]ethan-1-ol, Cyclin-K, ... | Authors: | Ferguson, A.D. | Deposit date: | 2017-09-21 | Release date: | 2017-12-27 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.06 Å) | Cite: | Structure-Based Design of Selective Noncovalent CDK12 Inhibitors. ChemMedChem, 13, 2018
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3LPE
| Crystal structure of Spt4/5NGN heterodimer complex from Methanococcus jannaschii | Descriptor: | DNA-directed RNA polymerase subunit E'', Putative transcription antitermination protein nusG, ZINC ION | Authors: | Hirtreiter, A, Damsma, G.E, Cheung, A.C.M, Klose, D, Grohmann, D, Vojnic, E, Martin, A.C.R, Cramer, P, Werner, F. | Deposit date: | 2010-02-05 | Release date: | 2010-03-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Spt4/5 stimulates transcription elongation through the RNA polymerase clamp coiled-coil motif. Nucleic Acids Res., 38, 2010
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6KX6
| Crystal structure of mouse Cryptochrome 1 in complex with KL101 compound | Descriptor: | Cryptochrome-1, ~{N}-[2-(2,4-dimethylphenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-3,4-dimethyl-benzamide | Authors: | Miller, S.A, Aikawa, Y, Hirota, T. | Deposit date: | 2019-09-10 | Release date: | 2020-04-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Isoform-selective regulation of mammalian cryptochromes. Nat.Chem.Biol., 16, 2020
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5UGQ
| Crystal Structure of Hip1 (Rv2224c) | Descriptor: | Carboxylesterase A | Authors: | Naffin-Olivos, J.L, Daab, A, White, A, Goldfarb, N, Milne, A.C, Liu, D, Dunn, B.M, Rengarajan, J, Petsko, G.A, Ringe, D. | Deposit date: | 2017-01-09 | Release date: | 2017-04-12 | Last modified: | 2019-12-11 | Method: | X-RAY DIFFRACTION (2.609 Å) | Cite: | Structure Determination of Mycobacterium tuberculosis Serine Protease Hip1 (Rv2224c). Biochemistry, 56, 2017
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3L6B
| X-ray crystal structure of human serine racemase in complex with malonate a potent inhibitor | Descriptor: | MALONATE ION, MANGANESE (II) ION, PYRIDOXAL-5'-PHOSPHATE, ... | Authors: | Smith, M.A, Barker, J, Mack, V, Ebneth, A, Moraes, I, Felicetti, B, Cesura, A. | Deposit date: | 2009-12-23 | Release date: | 2010-01-26 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The structure of mammalian serine racemase: evidence for conformational changes upon inhibitor binding. J.Biol.Chem., 285, 2010
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3L6Q
| Crystal structure of the N-terminal domain of HSP70 from Cryptosporidium parvum (CGD2_20) | Descriptor: | Heat shock 70 (HSP70) protein, MAGNESIUM ION, SULFATE ION | Authors: | Pizarro, J.C, Wernimont, A.K, Hutchinson, A, Sullivan, H, Lew, J, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Hui, R, Hills, T, Structural Genomics Consortium (SGC) | Deposit date: | 2009-12-24 | Release date: | 2010-02-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Crystal structure of the N-terminal domain of HSP70 from Cryptosporidium parvum (CGD2_20) To be Published
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7REY
| MYCOBACTERIUM ABSCESSUS TRNA METHYLTRANSFERASE IN APO FORM | Descriptor: | SODIUM ION, tRNA (guanine-N(1)-)-methyltransferase | Authors: | Prucha, G.R, Ismail, M, Suske, A, Das, B, Oz, M, Perez, A, Bolen, R, Jayaraman, S, Stojanoff, V, Halloran, J. | Deposit date: | 2021-07-13 | Release date: | 2023-01-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Crystal structure of divalent Mg2+ dependent Mycobacterium abscessus tRNA (m1 G37) Methyltransferase (TrmD) To Be Published
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5AB3
| S.enterica HisA mutant D7N, D10G, dup13-15, Q24L, G102A | Descriptor: | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, SODIUM ION, [(2R,3S,4R,5R)-5-[4-AMINOCARBONYL-5-[[(Z)-[(3R,4R)-3,4-DIHYDROXY-2-OXO-5-PHOSPHONOOXY-PENTYL]IMINOMETHYL]AMINO]IMIDAZOL-1-YL]-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL DIHYDROGEN PHOSPHATE | Authors: | Guo, X, Soderholm, A, Newton, M, Nasvall, J, Andersson, D, Patrick, W, Selmer, M. | Deposit date: | 2015-07-31 | Release date: | 2016-09-28 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.803 Å) | Cite: | Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6AUC
| Artificial metalloproteins containing a Co4O4 active site - 2xm-Sav | Descriptor: | N-biotin-C-Co4(mu3-O)4(Py)4(H2O)4-beta-alanine, Streptavidin | Authors: | Olshansky, L, Vallapurackal, J, Huerta-Lavorie, R, Tilley, T.D, Borovik, A.S. | Deposit date: | 2017-08-31 | Release date: | 2018-02-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Artificial Metalloproteins Containing Co J. Am. Chem. Soc., 140, 2018
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4Y6Q
| Human SIRT2 in complex with 2-O-myristoyl-ADP-ribose | Descriptor: | NAD-dependent protein deacetylase sirtuin-2, ZINC ION, [(2S,3R,4R,5R)-5-[[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxymethyl]-2,4-bis(oxidanyl)oxolan-3-yl] tetradecanoate | Authors: | Kudo, N, Ito, A, Yoshida, M. | Deposit date: | 2015-02-13 | Release date: | 2016-01-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Kinetic and Structural Basis for Acyl-Group Selectivity and NAD(+) Dependence in Sirtuin-Catalyzed Deacylation. Biochemistry, 54, 2015
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5A6S
| Crystal structure of the CTP1L endolysin reveals how its activity is regulated by a secondary translation product | Descriptor: | ENDOLYSIN, GLYCEROL, PENTAETHYLENE GLYCOL, ... | Authors: | Dunne, M, Leicht, S, Krichel, B, Mertens, H.D.T, Thompson, A, Krijgsveld, J, Svergun, D.I, GomezTorres, N, Garde, S, Uetrecht, C, Narbad, A, Mayer, M.J, Meijers, R. | Deposit date: | 2015-07-01 | Release date: | 2015-12-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structure of the Ctp1L Endolysin Reveals How its Activity is Regulated by a Secondary Translation Product. J.Biol.Chem., 291, 2016
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3LUQ
| The Crystal Structure of a PAS Domain from a Sensory Box Histidine Kinase Regulator from Geobacter sulfurreducens to 2.5A | Descriptor: | SULFATE ION, Sensor protein, TRIETHYLENE GLYCOL | Authors: | Stein, A.J, Weger, A, Duggan, E, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2010-02-18 | Release date: | 2010-03-16 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | The Crystal Structure of a PAS Domain from a Sensory Box Histidine Kinase Regulator from Geobacter sulfurreducens to 2.5A To be Published
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5GYL
| Structure of Cicer arietinum 11S gloubulin | Descriptor: | legumin-like protein | Authors: | Zhou, A, Zhang, F. | Deposit date: | 2016-09-22 | Release date: | 2017-10-04 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystallization and crystallographic studies of a novel chickpea 11S globulin. Acta Crystallogr.,Sect.F, 78, 2022
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6AY6
| Naegleria fowleri CYP51-voriconazole complex | Descriptor: | CYP51, sterol 14alpha-demethylase, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Debnath, A, Calvet, C.M, Jennings, G, Zhou, W, Aksenov, A, Luth, M, Abagyan, R, Nes, W.D, McKerrow, J.H, Podust, L.M. | Deposit date: | 2017-09-07 | Release date: | 2017-11-22 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | CYP51 is an essential drug target for the treatment of primary amoebic meningoencephalitis (PAM). PLoS Negl Trop Dis, 11, 2017
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5A6B
| GH20C, Beta-hexosaminidase from Streptococcus pneumoniae in complex with PUGNAc | Descriptor: | MAGNESIUM ION, N-ACETYL-BETA-D-GLUCOSAMINIDASE, O-(2-ACETAMIDO-2-DEOXY D-GLUCOPYRANOSYLIDENE) AMINO-N-PHENYLCARBAMATE | Authors: | Cid, M, Robb, C.S, Higgins, M.A, Boraston, A.B. | Deposit date: | 2015-06-24 | Release date: | 2015-09-23 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | A Second beta-Hexosaminidase Encoded in the Streptococcus pneumoniae Genome Provides an Expanded Biochemical Ability to Degrade Host Glycans. J. Biol. Chem., 290, 2015
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6SH0
| Crystal structure of AcAChBP in complex with anatoxin | Descriptor: | 1-[(1R,6R)-9-azabicyclo[4.2.1]non-2-en-2-yl]ethanone, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | Authors: | Hunter, W.N, Dawson, A, Parker, H. | Deposit date: | 2019-08-05 | Release date: | 2020-08-26 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Delineating the activity of the potent nicotinic acetylcholine receptor agonists (+)-anatoxin-a and (-)-hosieine-A Acta Crystallogr.,Sect.F, 2022
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5AFJ
| alpha7-AChBP in complex with lobeline and fragment 1 | Descriptor: | (3S)-6-(4-bromophenyl)-3-hydroxy-1,3-dimethyl-2,3-dihydropyridin-4(1H)-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINE-BINDING PROTEIN, ... | Authors: | Spurny, R, Debaveye, S, Farinha, A, Veys, K, Gossas, T, Atack, J, Bertrand, D, Kemp, J, Vos, A, Danielson, U.H, Tresadern, G, Ulens, C. | Deposit date: | 2015-01-22 | Release date: | 2015-05-06 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Molecular Blueprint of Allosteric Binding Sites in a Homologue of the Agonist-Binding Domain of the Alpha7 Nicotinic Acetylcholine Receptor. Proc.Natl.Acad.Sci.USA, 112, 2015
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6F89
| Structure of H234A/Y235A P.abyssi Sua5 | Descriptor: | BICARBONATE ION, THREONINE, Threonylcarbamoyl-AMP synthase | Authors: | Pichard-Kostuch, A, Zhang, W, Liger, D, Daugeron, M.C, Letoquart, J, Li de la Sierra-Gallay, I, Forterre, P, Collinet, B, van Tilbeurgh, H, Basta, T. | Deposit date: | 2017-12-12 | Release date: | 2018-04-25 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | Structure-function analysis of Sua5 protein reveals novel functional motifs required for the biosynthesis of the universal t6A tRNA modification. RNA, 24, 2018
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5KQR
| Structure of NS5 methyltransferase from Zika virus bound to S-adenosylmethionine | Descriptor: | CHLORIDE ION, Methyltransferase, PHOSPHATE ION, ... | Authors: | Jain, R, Coloma, J, Rajashankar, K.R, Aggarwal, A.K. | Deposit date: | 2016-07-06 | Release date: | 2016-09-14 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.331 Å) | Cite: | Structures of NS5 Methyltransferase from Zika Virus. Cell Rep, 16, 2016
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4RHN
| HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN (HINT) FROM RABBIT COMPLEXED WITH ADENOSINE | Descriptor: | HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN, alpha-D-ribofuranose | Authors: | Brenner, C, Garrison, P, Gilmour, J, Peisach, D, Ringe, D, Petsko, G.A, Lowenstein, J.M. | Deposit date: | 1997-02-26 | Release date: | 1997-06-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structures of HINT demonstrate that histidine triad proteins are GalT-related nucleotide-binding proteins. Nat.Struct.Biol., 4, 1997
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6SBW
| CdbA Form One | Descriptor: | CdbA | Authors: | Lovering, A.L, Cadby, I.T. | Deposit date: | 2019-07-22 | Release date: | 2020-04-22 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | CdbA is a DNA-binding protein and c-di-GMP receptor important for nucleoid organization and segregation in Myxococcus xanthus. Nat Commun, 11, 2020
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6BCD
| Crystal structure of Rev7-K44A/R124A/A135D in complex with Rev3-RBM2 (residues 1988-2014) | Descriptor: | DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B | Authors: | Rizzo, A.A, Hao, B, Li, Y, Korzhnev, D.M. | Deposit date: | 2017-10-20 | Release date: | 2018-08-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | Rev7 dimerization is important for assembly and function of the Rev1/Pol zeta translesion synthesis complex. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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1NDN
| MOLECULAR STRUCTURE OF NICKED DNA. MODEL T4 | Descriptor: | DNA (5'-D(*CP*GP*CP*GP*AP*AP*AP*AP*CP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*GP*TP*T)-3'), DNA (5'-D(*TP*TP*CP*GP*CP*G)-3') | Authors: | Aymani, J, Coll, M, Van Der Marel, G.A, Van Boom, J.H, Wang, A.H.-J, Rich, A. | Deposit date: | 1992-01-15 | Release date: | 1992-07-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Molecular structure of nicked DNA: a substrate for DNA repair enzymes. Proc.Natl.Acad.Sci.USA, 87, 1990
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