5AB3

S.enterica HisA mutant D7N, D10G, dup13-15, Q24L, G102A

Summary for 5AB3

Descriptor1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, [(2R,3S,4R,5R)-5-[4-AMINOCARBONYL-5-[[(Z)-[(3R,4R)-3,4-DIHYDROXY-2-OXO-5-PHOSPHONOOXY-PENTYL]IMINOMETHYL]AMINO]IMIDAZOL-1-YL]-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL DIHYDROGEN PHOSPHATE, SODIUM ION, ... (4 entities in total)
Functional Keywordsisomerase, hisa, protein evolution, iad model, trpf
Biological sourceSalmonella enterica subsp. enterica serovar Cubana str. 76814
Total number of polymer chains3
Total molecular weight84106.21
Authors
Guo, X.,Soderholm, A.,Newton, M.,Nasvall, J.,Andersson, D.,Patrick, W.,Selmer, M. (deposition date: 2015-07-31, release date: 2016-09-28, Last modification date: 2018-06-06)
Primary citation
Newton, M.S.,Guo, X.,Soderholm, A.,Nasvall, J.,Lundstrom, P.,Andersson, D.I.,Selmer, M.,Patrick, W.M.
Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes.
Proc. Natl. Acad. Sci. U.S.A., 114:4727-4732, 2017
PubMed: 28416687 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1618552114
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.803 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.212300.5%1.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 5ab3
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Molmil generated image of 5ab3
rotated about x axis by 90°
Molmil generated image of 5ab3
rotated about y axis by 90°