5AB3
S.enterica HisA mutant D7N, D10G, dup13-15, Q24L, G102A
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000105 | biological_process | L-histidine biosynthetic process |
| A | 0003949 | molecular_function | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0016853 | molecular_function | isomerase activity |
| B | 0000105 | biological_process | L-histidine biosynthetic process |
| B | 0003949 | molecular_function | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0016853 | molecular_function | isomerase activity |
| C | 0000105 | biological_process | L-histidine biosynthetic process |
| C | 0003949 | molecular_function | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0008652 | biological_process | amino acid biosynthetic process |
| C | 0016853 | molecular_function | isomerase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 34 |
| Details | BINDING SITE FOR RESIDUE 2ER A 1245 |
| Chain | Residue |
| A | ASN7 |
| A | ASP176 |
| A | GLY177 |
| A | SER202 |
| A | GLY203 |
| A | GLY204 |
| A | ILE223 |
| A | GLY225 |
| A | ARG226 |
| A | HOH2006 |
| A | HOH2011 |
| A | VAL15 |
| A | HOH2016 |
| A | HOH2045 |
| A | HOH2076 |
| A | HOH2077 |
| A | HOH2078 |
| A | HOH2117 |
| A | HOH2120 |
| A | HOH2151 |
| A | HOH2154 |
| A | HOH2155 |
| A | ARG15 |
| A | HOH2156 |
| A | HOH2180 |
| A | HOH2181 |
| A | HOH2193 |
| A | HOH2194 |
| A | TYR21 |
| A | GLY81 |
| A | ALA102 |
| A | SER103 |
| A | ALA127 |
| A | ASP129 |
| site_id | AC2 |
| Number of Residues | 36 |
| Details | BINDING SITE FOR RESIDUE 2ER B 1245 |
| Chain | Residue |
| B | ASN7 |
| B | VAL15 |
| B | ARG15 |
| B | TYR21 |
| B | VAL49 |
| B | GLY80 |
| B | GLY81 |
| B | ALA102 |
| B | SER103 |
| B | ALA127 |
| B | ASP129 |
| B | ASP176 |
| B | GLY177 |
| B | SER202 |
| B | GLY203 |
| B | GLY204 |
| B | ILE223 |
| B | GLY225 |
| B | ARG226 |
| B | HOH2002 |
| B | HOH2007 |
| B | HOH2012 |
| B | HOH2045 |
| B | HOH2066 |
| B | HOH2068 |
| B | HOH2073 |
| B | HOH2083 |
| B | HOH2104 |
| B | HOH2125 |
| B | HOH2134 |
| B | HOH2135 |
| B | HOH2136 |
| B | HOH2155 |
| B | HOH2157 |
| B | HOH2175 |
| B | HOH2177 |
| site_id | AC3 |
| Number of Residues | 31 |
| Details | BINDING SITE FOR RESIDUE 2ER C 1245 |
| Chain | Residue |
| C | HOH2144 |
| C | HOH2162 |
| C | ASN7 |
| C | VAL15 |
| C | ARG15 |
| C | TYR21 |
| C | VAL49 |
| C | GLY81 |
| C | ALA102 |
| C | SER103 |
| C | ALA127 |
| C | ASP129 |
| C | ASP176 |
| C | GLY177 |
| C | SER202 |
| C | GLY203 |
| C | GLY204 |
| C | GLY225 |
| C | ARG226 |
| C | HOH2008 |
| C | HOH2011 |
| C | HOH2043 |
| C | HOH2059 |
| C | HOH2061 |
| C | HOH2063 |
| C | HOH2080 |
| C | HOH2090 |
| C | HOH2115 |
| C | HOH2119 |
| C | HOH2120 |
| C | HOH2143 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA B 1246 |
| Chain | Residue |
| B | MET1 |
| B | ILE2 |
| B | GLN243 |
| B | HOH2001 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA A 1246 |
| Chain | Residue |
| A | MET1 |
| A | ILE2 |
| A | GLN243 |
| A | HOH2004 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA C 1246 |
| Chain | Residue |
| C | MET1 |
| C | ILE2 |
| C | HOH2038 |
| C | HOH2161 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA B 1247 |
| Chain | Residue |
| A | PRO31 |
| A | LEU32 |
| B | GLN155 |
| B | HOH2111 |
