3L6B
X-ray crystal structure of human serine racemase in complex with malonate a potent inhibitor
Summary for 3L6B
Entry DOI | 10.2210/pdb3l6b/pdb |
Related | 3L6C 3L6R |
Descriptor | Serine racemase, PYRIDOXAL-5'-PHOSPHATE, MANGANESE (II) ION, ... (5 entities in total) |
Functional Keywords | pyridoxal phosphate, plp, serine racemase, isomerase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 37859.99 |
Authors | Smith, M.A.,Barker, J.,Mack, V.,Ebneth, A.,Moraes, I.,Felicetti, B.,Cesura, A. (deposition date: 2009-12-23, release date: 2010-01-26, Last modification date: 2024-04-03) |
Primary citation | Smith, M.A.,Mack, V.,Ebneth, A.,Moraes, I.,Felicetti, B.,Wood, M.,Schonfeld, D.,Mather, O.,Cesura, A.,Barker, J. The structure of mammalian serine racemase: evidence for conformational changes upon inhibitor binding. J.Biol.Chem., 285:12873-12881, 2010 Cited by PubMed: 20106978DOI: 10.1074/jbc.M109.050062 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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