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8AOU
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BU of 8aou by Molmil
Solution NMR structure of full-length Nsp1 from SARS-CoV-2.
Descriptor: Host translation inhibitor nsp1
Authors:Wang, Y, Kirkpatrick, J.P, Carlomagno, T.
Deposit date:2022-08-08
Release date:2022-12-28
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Structural insights into the activity regulation of full-length non-structural protein 1 from SARS-CoV-2.
Structure, 31, 2023
2R8G
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BU of 2r8g by Molmil
Selectivity of Nucleoside Triphosphate Incorporation Opposite 1,N2-Propanodeoxyguanosine (PdG) by the Sulfolobus solfataricus DNA Polymerase Dpo4 Polymerase
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*DGP*DGP*DGP*DGP*DGP*DAP*DAP*DGP*DGP*DAP*DTP*DTP*DT)-3', 5'-D(*DTP*DCP*DAP*DCP*(P)P*DGP*DAP*DAP*DAP*DTP*DCP*DCP*DTP*DTP*DCP*DCP*DCP*DCP*DC)-3', ...
Authors:Wang, Y, Saleh, S, Marnette, L.J, Egli, M, Stone, M.P.
Deposit date:2007-09-10
Release date:2008-07-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Insertion of dNTPs opposite the 1,N2-propanodeoxyguanosine adduct by Sulfolobus solfataricus P2 DNA polymerase IV
Biochemistry, 47, 2008
2ROU
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BU of 2rou by Molmil
Stereospecific Conformations of N2-dG 1R-trans-anti-Benzo[c]phenanthrene DNA Adducts: 3'-Intercalation of the 1R Adduct and 5'-Minor Groove Orientation of the 1S Adduct in an Iterated (CG)3 Repeat
Descriptor: (1R)-1,2,3,4-TETRAHYDRO-BENZO[C]PHENANTHRENE-2,3,4-TRIOL, DNA (5'-D(*DAP*DTP*DCP*DGP*DCP*DGP*DCP*DGP*DGP*DCP*DAP*DTP*DG)-3'), DNA (5'-D(*DCP*DAP*DTP*DGP*DCP*DCP*DGP*DCP*DGP*DCP*DGP*DAP*DT)-3')
Authors:Wang, Y, Kroth, H, Yagi, H, Sayer, J.M, Kumar, S, Jerina, D.M, Stone, M.P.
Deposit date:2008-04-20
Release date:2009-03-03
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:3'-Intercalation of a N2-dG 1R-trans-anti-benzo[c]phenanthrene DNA adduct in an iterated (CG)3 repeat
Chem.Res.Toxicol., 21, 2008
6K3H
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BU of 6k3h by Molmil
Crystallographic Analysis of Nucleoside Diphosphate Kinase (NDK) from Aspergillus Flavus
Descriptor: Nucleoside diphosphate kinase
Authors:Wang, Y, Wang, S, Wang, S.H.
Deposit date:2019-05-18
Release date:2019-07-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.179 Å)
Cite:Molecular and structural basis of nucleoside diphosphate kinase-mediated regulation of spore and sclerotia development in the fungusAspergillus flavus.
J.Biol.Chem., 294, 2019
6JOH
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BU of 6joh by Molmil
The crystal of nucleoside diphosphate kinase from Aspergillus flavus
Descriptor: Nucleoside diphosphate kinase
Authors:Wang, Y, Wang, S, Wang, S.H.
Deposit date:2019-03-21
Release date:2020-01-29
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular and structural basis of Nucleoside Diphosphate Kinase regulating the spores and sclerotia development in Aspergillus flavus
To Be Published
3KCV
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BU of 3kcv by Molmil
Structure of formate channel
Descriptor: Probable formate transporter 1
Authors:Wang, Y, Huang, Y, Wang, J, Yan, N, Shi, Y.
Deposit date:2009-10-22
Release date:2009-12-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.198 Å)
Cite:Structure of the formate transporter FocA reveals a pentameric aquaporin-like channel
Nature, 462, 2009
3KCU
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BU of 3kcu by Molmil
Structure of formate channel
Descriptor: 2-(6-(2-CYCLOHEXYLETHOXY)-TETRAHYDRO-4,5-DIHYDROXY-2(HYDROXYMETHYL)-2H-PYRAN-3-YLOXY)-TETRAHYDRO-6(HYDROXYMETHYL)-2H-PY RAN-3,4,5-TRIOL, Probable formate transporter 1
Authors:Wang, Y, Huang, Y, Wang, J, Yan, N, Shi, Y.
Deposit date:2009-10-22
Release date:2009-12-01
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.243 Å)
Cite:Structure of the formate transporter FocA reveals a pentameric aquaporin-like channel
Nature, 462, 2009
8HBS
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BU of 8hbs by Molmil
Crystal of rAlfNmt
Descriptor: Glycylpeptide N-tetradecanoyltransferase
Authors:Wang, Y, Wang, S.
Deposit date:2022-10-30
Release date:2023-03-08
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:N -Myristoyltransferase, a Potential Antifungal Candidate Drug-Target for Aspergillus flavus.
Microbiol Spectr, 11, 2023
1CW5
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BU of 1cw5 by Molmil
SOLUTION STRUCTURE OF CARNOBACTERIOCIN B2
Descriptor: TYPE IIA BACTERIOCIN CARNOBACTERIOCIN B2
Authors:Wang, Y, Henz, M.E, Gallagher, N.L.F, Chai, S, Yan, L.Z, Gibbs, A.C, Stiles, M.E, Wishart, D.S, Vederas, J.C.
Deposit date:1999-08-25
Release date:1999-09-07
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Solution structure of carnobacteriocin B2 and implications for structure-activity relationships among type IIa bacteriocins from lactic acid bacteria.
Biochemistry, 38, 1999
1CW6
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BU of 1cw6 by Molmil
REFINED SOLUTION STRUCTURE OF LEUCOCIN A
Descriptor: TYPE IIA BACTERIOCIN LEUCOCIN A
Authors:Wang, Y, Henz, M.E, Gallagher, N.L.F, Chai, S, Yan, L.Z, Gibbs, A.C, Stiles, M.E, Wishart, D.S, Vederas, J.C.
Deposit date:1999-08-25
Release date:1999-09-08
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Solution structure of carnobacteriocin B2 and implications for structure-activity relationships among type IIa bacteriocins from lactic acid bacteria.
Biochemistry, 38, 1999
1DE1
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BU of 1de1 by Molmil
NMR STRUCTURES OF OXIDIZED BACTERIOPHAGE T4 GLUTAREDOXIN
Descriptor: GLUTAREDOXIN
Authors:Wang, Y, Amegbey, G, Wishart, D.S.
Deposit date:1999-11-12
Release date:1999-11-24
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Solution structures of reduced and oxidized bacteriophage T4 glutaredoxin.
J.Biomol.Nmr, 29, 2004
1DE2
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BU of 1de2 by Molmil
NMR STRUCTURES OF REDUCED BACTERIOPHAGE T4 GLUTAREDOXIN
Descriptor: GLUTAREDOXIN
Authors:Wang, Y, Wishart, D.S.
Deposit date:1999-11-12
Release date:1999-11-24
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structures of reduced and oxidized bacteriophage T4 glutaredoxin.
J.Biomol.Nmr, 29, 2004
5IJC
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BU of 5ijc by Molmil
The crystal structure of mouse TLR4/MD-2/neoseptin-3 complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte antigen 96, ...
Authors:Wang, Y, Su, L, Morin, M.D, Jones, B.T, Whitby, L.R, Surakattula, M, Huang, H, Shi, H, Choi, J.H, Wang, K, Moresco, E.M, Berger, M, Zhan, X, Zhang, H, Boger, D.L, Beutler, B.
Deposit date:2016-03-01
Release date:2016-04-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Proc.Natl.Acad.Sci.USA, 113, 2016
5IJB
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BU of 5ijb by Molmil
The ligand-free structure of the mouse TLR4/MD-2 complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte antigen 96, ...
Authors:Wang, Y, Su, L, Morin, M.D, Jones, B.T, Whitby, L.R, Surakattula, M, Huang, H, Shi, H, Choi, J.H, Wang, K, Moresco, E.M, Berger, M, Zhan, X, Zhang, H, Boger, D.L, Beutler, B.
Deposit date:2016-03-01
Release date:2016-04-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Proc.Natl.Acad.Sci.USA, 113, 2016
5IJD
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BU of 5ijd by Molmil
The crystal structure of mouse TLR4/MD-2/lipid A complex
Descriptor: (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Wang, Y, Su, L, Morin, M.D, Jones, B.T, Whitby, L.R, Surakattula, M, Huang, H, Shi, H, Choi, J.H, Wang, K, Moresco, E.M, Berger, M, Zhan, X, Zhang, H, Boger, D.L, Beutler, B.
Deposit date:2016-03-01
Release date:2016-04-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Proc.Natl.Acad.Sci.USA, 113, 2016
5BMV
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BU of 5bmv by Molmil
CRYSTAL STRUCTURE OF TUBULIN-STATHMIN-TTL-Vinblastine COMPLEX
Descriptor: (2ALPHA,2'BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Wang, Y, Chen, Q, Zhang, R.
Deposit date:2015-05-23
Release date:2016-07-13
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Insights into the Pharmacophore of Vinca Domain Inhibitors of Microtubules.
Mol.Pharmacol., 89, 2016
8GAP
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BU of 8gap by Molmil
Structure of LARP7 protein p65-telomerase RNA complex in telomerase
Descriptor: Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ...
Authors:Wang, Y, He, Y, Wang, Y, Yang, Y, Singh, M, Eichhorn, C.D, Zhou, Z.H, Feigon, J.
Deposit date:2023-02-23
Release date:2023-06-28
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of LARP7 Protein p65-telomerase RNA Complex in Telomerase Revealed by Cryo-EM and NMR.
J.Mol.Biol., 435, 2023
4ZHQ
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BU of 4zhq by Molmil
Crystal structure of Tubulin-Stathmin-TTL-MMAE Complex
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ...
Authors:Wang, Y, Zhang, R.
Deposit date:2015-04-26
Release date:2016-07-27
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural Insights into the Pharmacophore of Vinca Domain Inhibitors of Microtubules
Mol.Pharmacol., 89, 2016
4ZI7
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BU of 4zi7 by Molmil
CRYSTAL STRUCTURE OF TUBULIN-STATHMIN-TTL-HTI286 COMPLEX
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ...
Authors:Wang, Y, Zhang, R.
Deposit date:2015-04-27
Release date:2016-07-27
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Structural Insights into the Pharmacophore of Vinca Domain Inhibitors of Microtubules
Mol.Pharmacol., 89, 2016
4ZOL
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BU of 4zol by Molmil
Crystal Structure of Tubulin-Stathmin-TTL-Tubulysin M Complex
Descriptor: (2R,4R)-4-{[(2-{(1R,3R)-1-(acetyloxy)-4-methyl-3-[methyl(N-{[(2S)-1-methylpiperidin-2-yl]carbonyl}-D-isoleucyl)amino]pentyl}-1,3-thiazol-4-yl)carbonyl]amino}-2-methyl-5-phenylpentanoic acid, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Wang, Y, Zhang, R.
Deposit date:2015-05-06
Release date:2016-07-27
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Insights into the Pharmacophore of Vinca Domain Inhibitors of Microtubules
Mol.Pharmacol., 89, 2016
5ZQ7
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BU of 5zq7 by Molmil
SidE-Ubi-NAD
Descriptor: ADENOSINE MONOPHOSPHATE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SidE, ...
Authors:Wang, Y, Gao, A, Gao, P.
Deposit date:2018-04-17
Release date:2018-05-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.847 Å)
Cite:Structural Insights into Non-canonical Ubiquitination Catalyzed by SidE.
Cell, 173, 2018
5ZQ6
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BU of 5zq6 by Molmil
SidE-Ubi-ADPr
Descriptor: ADENOSINE-5'-DIPHOSPHATE, SidE, Ubiquitin
Authors:Wang, Y, Gao, A, Gao, P.
Deposit date:2018-04-17
Release date:2018-05-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.009 Å)
Cite:Structural Insights into Non-canonical Ubiquitination Catalyzed by SidE.
Cell, 173, 2018
5ZRX
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BU of 5zrx by Molmil
Crystal Structure of EphA2/SHIP2 Complex
Descriptor: Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2,Ephrin type-A receptor 2
Authors:Wang, Y, Shang, Y, Li, J, Chen, W, Li, G, Wan, J, Liu, W, Zhang, M.
Deposit date:2018-04-25
Release date:2018-05-30
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Specific Eph receptor-cytoplasmic effector signaling mediated by SAM-SAM domain interactions.
Elife, 7, 2018
5ZRY
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BU of 5zry by Molmil
Crystal Structure of EphA6/Odin Complex
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Ankyrin repeat and SAM domain-containing protein 1A,Ephrin type-A receptor 6, ...
Authors:Wang, Y, Shang, Y, Li, J, Chen, W, Li, G, Wan, J, Liu, W, Zhang, M.
Deposit date:2018-04-25
Release date:2018-05-30
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Specific Eph receptor-cytoplasmic effector signaling mediated by SAM-SAM domain interactions.
Elife, 7, 2018
5ZRZ
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BU of 5zrz by Molmil
Crystal Structure of EphA5/SAMD5 Complex
Descriptor: Ephrin type-A receptor 5, Sterile alpha motif domain-containing protein 5
Authors:Wang, Y, Shang, Y, Li, J, Chen, W, Li, G, Wan, J, Liu, W, Zhang, M.
Deposit date:2018-04-25
Release date:2018-05-30
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Specific Eph receptor-cytoplasmic effector signaling mediated by SAM-SAM domain interactions.
Elife, 7, 2018

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