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6UU5
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BU of 6uu5 by Molmil
E. coli sigma-S transcription initiation complex with a 6-nt RNA ("Old" crystal soaked with GTP, UTP, CTP, and dinucleotide GpA for 30 minutes)
Descriptor: DIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Zuo, Y, De, S, Steitz, T.A.
Deposit date:2019-10-30
Release date:2020-08-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (5.403 Å)
Cite:Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020
6A67
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BU of 6a67 by Molmil
Crystal structure of influenza A virus H5 hemagglutinin globular head in complex with the Fab of antibody FLD21.140
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, FLD21.140 Heavy Chain, FLD21.140 Light Chain, ...
Authors:Wang, P, Zuo, Y, Sun, J, Zhang, L, Wang, X.
Deposit date:2018-06-26
Release date:2018-08-29
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Complementary recognition of the receptor-binding site of highly pathogenic H5N1 influenza viruses by two human neutralizing antibodies.
J. Biol. Chem., 293, 2018
2IGI
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BU of 2igi by Molmil
Crystal Structure of E. coli Oligoribonuclease
Descriptor: ACETIC ACID, CADMIUM ION, Oligoribonuclease, ...
Authors:Zuo, Y, Malhotra, A.
Deposit date:2006-09-22
Release date:2007-10-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of Oligoribonuclease, the lone essential exoribonuclease in Escherichia coli
To be Published
4S20
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BU of 4s20 by Molmil
Structural basis for transcription reactivation by RapA
Descriptor: 5'-D(P*AP*CP*GP*AP*CP*TP*GP*AP*GP*CP*CP*GP*AP*TP*G)-3', 5'-R(P*AP*UP*CP*GP*GP*CP*UP*CP*A)-3', DNA-directed RNA polymerase subunit alpha, ...
Authors:Liu, B, Zuo, Y, Steitz, T.A.
Deposit date:2015-01-16
Release date:2015-02-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (4.7 Å)
Cite:Structural basis for transcription reactivation by RapA.
Proc.Natl.Acad.Sci.USA, 112, 2015
1YTA
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BU of 1yta by Molmil
Crystal Structure of Oligoribonuclease, the lone essential exoribonuclease in Escherichia coli
Descriptor: CITRATE ANION, Oligoribonuclease
Authors:Fiedler, T.J, Zuo, Y, Malhotra, A.
Deposit date:2005-02-10
Release date:2006-02-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of Oligoribonuclease, the lone essential exoribonuclease in Escherichia coli
To be Published
5IPN
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BU of 5ipn by Molmil
SigmaS-transcription initiation complex with 4-nt nascent RNA
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Liu, B, Zuo, Y, Steitz, T.A.
Deposit date:2016-03-09
Release date:2016-03-30
Last modified:2016-06-22
Method:X-RAY DIFFRACTION (4.61 Å)
Cite:Structures of E. coli sigma S-transcription initiation complexes provide new insights into polymerase mechanism.
Proc.Natl.Acad.Sci.USA, 113, 2016
5IPL
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BU of 5ipl by Molmil
SigmaS-transcription initiation complex with 4-nt nascent RNA
Descriptor: DIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Liu, B, Zuo, Y, Steitz, T.A.
Deposit date:2016-03-09
Release date:2016-03-30
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structures of E. coli sigma S-transcription initiation complexes provide new insights into polymerase mechanism.
Proc.Natl.Acad.Sci.USA, 113, 2016
5IPM
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BU of 5ipm by Molmil
SigmaS-transcription initiation complex with 4-nt nascent RNA
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Liu, B, Zuo, Y, Steitz, T.A.
Deposit date:2016-03-09
Release date:2016-03-30
Last modified:2016-06-22
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Structures of E. coli sigma S-transcription initiation complexes provide new insights into polymerase mechanism.
Proc.Natl.Acad.Sci.USA, 113, 2016
6IUT
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BU of 6iut by Molmil
Crystal structure of influenza A virus H5 hemagglutinin globular head in complex with the Fab of antibody AVFluIgG01
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, AVFluIgG01 Heavy Chain, ...
Authors:Wang, P, Zuo, Y, Sun, J, Zhang, L, Wang, X.
Deposit date:2018-11-30
Release date:2019-01-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and functional definition of a vulnerable site on the hemagglutinin of highly pathogenic avian influenza A virus H5N1.
J. Biol. Chem., 294, 2019
6IUV
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BU of 6iuv by Molmil
Crystal structure of influenza A virus H5 hemagglutinin globular head in complex with the Fab of antibody 3C11
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 3C11 Heavy Chain, 3C11 Light Chain, ...
Authors:Wang, P, Zuo, Y, Sun, J, Zhang, L, Wang, X.
Deposit date:2018-11-30
Release date:2019-01-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.332 Å)
Cite:Structural and functional definition of a vulnerable site on the hemagglutinin of highly pathogenic avian influenza A virus H5N1.
J. Biol. Chem., 294, 2019
6LG9
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BU of 6lg9 by Molmil
crystal structure of the first bromodomain of human BRD4 in complex with compound BDF-2143
Descriptor: 2-azanyl-7-bromanyl-4-imidazol-1-yl-quinolin-8-ol, Bromodomain-containing protein 4
Authors:Xu, H, Zuo, Y.
Deposit date:2019-12-04
Release date:2020-12-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Lead-Opt: An efficient tool for structural optimization of lead compounds
To Be Published
6LG4
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BU of 6lg4 by Molmil
crystal structure of the first bromodomain of human BRD4 in complex with compound BDF-1024
Descriptor: 7-chloranyl-5-nitro-quinolin-8-ol, Bromodomain-containing protein 4
Authors:Xu, H, Zuo, Y, Zhang, H.
Deposit date:2019-12-04
Release date:2020-12-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Lead-Opt: An efficient tool for structural optimization of lead compounds
To Be Published
6LG8
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BU of 6lg8 by Molmil
crystal structure of the first bromodomain of human BRD4 in complex with compound BDF-2138
Descriptor: 2-azanyl-5-fluoranyl-4-imidazol-1-yl-quinolin-8-ol, Bromodomain-containing protein 4
Authors:Xu, H, Zuo, Y, Zhang, H.
Deposit date:2019-12-04
Release date:2020-12-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Lead-Opt: An efficient tool for structural optimization of lead compounds
To Be Published
6LG7
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BU of 6lg7 by Molmil
Crystal Structure of the first bromodomain of human BRD4 in complex with compound BDF-2030
Descriptor: 2-azanyl-6-fluoranyl-4-imidazol-1-yl-quinolin-8-ol, Bromodomain-containing protein 4
Authors:Xu, H, Zuo, Y.
Deposit date:2019-12-04
Release date:2020-12-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Lead-Opt: An efficient tool for structural optimization of lead compounds
To Be Published
6LG6
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BU of 6lg6 by Molmil
Crystal Structure of the first bromodomain of human BRD4 in complex with compound BDF-1021
Descriptor: Bromodomain-containing protein 4, N-[8-oxidanyl-4-(pyridin-2-ylamino)quinolin-2-yl]ethanamide
Authors:Xu, H, Zuo, Y.
Deposit date:2019-12-04
Release date:2020-12-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Lead-Opt: An efficient tool for structural optimization of lead compounds
To Be Published
6LG5
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BU of 6lg5 by Molmil
Crystal Structure of the first bromodomain of human BRD4 in complex with compound BDF-1038
Descriptor: 1-[(5-chloranyl-8-oxidanyl-quinolin-7-yl)methyl]pyrrolidin-2-one, Bromodomain-containing protein 4
Authors:Xu, H, Zuo, Y, Zhang, H.
Deposit date:2019-12-04
Release date:2020-12-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Lead-Opt: An efficient tool for structural optimization of lead compounds
To Be Published
2F96
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BU of 2f96 by Molmil
2.1 A crystal structure of Pseudomonas aeruginosa rnase T (Ribonuclease T)
Descriptor: MAGNESIUM ION, Ribonuclease T
Authors:Zheng, H, Chruszcz, M, Cymborowski, M, Wang, Y, Gorodichtchenskaia, E, Skarina, T, Guthrie, J, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
Deposit date:2005-12-05
Release date:2006-02-14
Last modified:2022-04-13
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Crystal Structure of RNase T, an Exoribonuclease Involved in tRNA Maturation and End Turnover.
Structure, 15, 2007
5DUP
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BU of 5dup by Molmil
Influenza A virus H5 hemagglutinin globular head in complex with antibody AVFluIgG03
Descriptor: AVFluIgG03 Heavy Chain, AVFluIgG03 Light Chain, Hemagglutinin
Authors:Zuo, T, Sun, J, Wang, G, Zhou, P, Wang, X, Zhang, L.
Deposit date:2015-09-20
Release date:2015-12-16
Method:X-RAY DIFFRACTION (3.052 Å)
Cite:Comprehensive analysis of antibody recognition in convalescent humans from highly pathogenic avian influenza H5N1 infection
Nat Commun, 6, 2015
5DUT
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BU of 5dut by Molmil
Influenza A virus H5 hemagglutinin globular head
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin
Authors:Zuo, T, Sun, J, Wang, G, Zhou, P, Wang, X, Zhang, L.
Deposit date:2015-09-20
Release date:2015-12-16
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Comprehensive analysis of antibody recognition in convalescent humans from highly pathogenic avian influenza H5N1 infection
Nat Commun, 6, 2015
5DUM
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BU of 5dum by Molmil
Crystal structure of influenza A virus H5 hemagglutinin globular head in complex with the Fab of antibody 65C6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 65C6 Heavy Chain, 65C6 Light Chain, ...
Authors:Sun, J, Zuo, T, Wang, G, Zhou, P, Zhang, L, Wang, X.
Deposit date:2015-09-19
Release date:2015-12-16
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.003 Å)
Cite:Comprehensive analysis of antibody recognition in convalescent humans from highly pathogenic avian influenza H5N1 infection
Nat Commun, 6, 2015
5DUR
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BU of 5dur by Molmil
Influenza A virus H5 hemagglutinin globular head in complex with antibody 100F4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy Chain of Antibody 100F4, Hemagglutinin, ...
Authors:Zuo, T, Sun, J, Wang, G, Zhou, P, Wang, X, Zhang, L.
Deposit date:2015-09-20
Release date:2015-12-16
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Comprehensive analysis of antibody recognition in convalescent humans from highly pathogenic avian influenza H5N1 infection
Nat Commun, 6, 2015
6STY
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BU of 6sty by Molmil
Human REXO2 exonuclease in complex with RNA.
Descriptor: CALCIUM ION, Oligoribonuclease, mitochondrial, ...
Authors:Malik, D, Szewczyk, M, Szczesny, R, Nowotny, M.
Deposit date:2019-09-12
Release date:2020-04-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Human REXO2 controls short mitochondrial RNAs generated by mtRNA processing and decay machinery to prevent accumulation of double-stranded RNA.
Nucleic Acids Res., 48, 2020
7E6G
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BU of 7e6g by Molmil
Crystal structure of diguanylate cyclase SiaD in complex with its activator SiaC from Pseudomonas aeruginosa
Descriptor: DUF1987 domain-containing protein, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ...
Authors:Zhou, J.S, Zhang, L, Zhang, L.
Deposit date:2021-02-22
Release date:2021-09-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural basis for diguanylate cyclase activation by its binding partner in Pseudomonas aeruginosa .
Elife, 10, 2021
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