6LG6
Crystal Structure of the first bromodomain of human BRD4 in complex with compound BDF-1021
Summary for 6LG6
Entry DOI | 10.2210/pdb6lg6/pdb |
Descriptor | Bromodomain-containing protein 4, N-[8-oxidanyl-4-(pyridin-2-ylamino)quinolin-2-yl]ethanamide (3 entities in total) |
Functional Keywords | brd4, inhibitor, complex, dna binding protein, transcription |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 15177.50 |
Authors | |
Primary citation | Xu, H.,Zuo, Y. Lead-Opt: An efficient tool for structural optimization of lead compounds To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.98 Å) |
Structure validation
Download full validation report