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5TCX
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BU of 5tcx by Molmil
Crystal structure of human tetraspanin CD81
分子名称: CD81 antigen, CHOLESTEROL
著者Zimmerman, B, McMillan, B.J, Seegar, T.C.M, Kruse, A.C, Blacklow, S.C.
登録日2016-09-16
公開日2016-11-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.955 Å)
主引用文献Crystal Structure of a Full-Length Human Tetraspanin Reveals a Cholesterol-Binding Pocket.
Cell, 167, 2016
4TSE
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BU of 4tse by Molmil
Crystal Structure of the Mib Repeat Domain of Mind bomb 1
分子名称: E3 ubiquitin-protein ligase MIB1
著者McMillan, B.J, Blacklow, S.C.
登録日2014-06-18
公開日2015-03-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.057 Å)
主引用文献A tail of two sites: a bipartite mechanism for recognition of notch ligands by mind bomb e3 ligases.
Mol.Cell, 57, 2015
6BDZ
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BU of 6bdz by Molmil
ADAM10 Extracellular Domain Bound by the 11G2 Fab
分子名称: 11G2 Fab Heavy Chain, 11G2 Fab Light Chain, CALCIUM ION, ...
著者Seegar, T.C.M.
登録日2017-10-24
公開日2017-12-27
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural Basis for Regulated Proteolysis by the alpha-Secretase ADAM10.
Cell, 171, 2017
6BE6
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BU of 6be6 by Molmil
ADAM10 Extracellular Domain
分子名称: CALCIUM ION, Disintegrin and metalloproteinase domain-containing protein 10, SULFATE ION, ...
著者Seegar, T.C.M.
登録日2017-10-24
公開日2017-12-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis for Regulated Proteolysis by the alpha-Secretase ADAM10.
Cell, 171, 2017
4XI7
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BU of 4xi7 by Molmil
Crystal structure of the MZM-REP domains of Mind bomb 1 in complex with Jagged1 N-box peptide
分子名称: E3 ubiquitin-protein ligase MIB1, Jagged 1 N-box peptide, SULFATE ION, ...
著者McMillan, B.J, Blacklow, S.C.
登録日2015-01-06
公開日2015-03-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.051 Å)
主引用文献A tail of two sites: a bipartite mechanism for recognition of notch ligands by mind bomb e3 ligases.
Mol.Cell, 57, 2015
4XIB
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BU of 4xib by Molmil
Crystal structure of the MZM-REP domains of Mind bomb 1 in complex with fly Delta N-box peptide
分子名称: Delta N-box peptide, E3 ubiquitin-protein ligase MIB1, SULFATE ION, ...
著者McMillan, B.J, Blacklow, S.C.
登録日2015-01-06
公開日2015-03-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.147 Å)
主引用文献A tail of two sites: a bipartite mechanism for recognition of notch ligands by mind bomb e3 ligases.
Mol.Cell, 57, 2015
4XI6
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BU of 4xi6 by Molmil
Crystal structure of the MZM-REP domains of Mind bomb 1
分子名称: E3 ubiquitin-protein ligase MIB1, SULFATE ION, ZINC ION
著者McMillan, B.J, Blacklow, S.C.
登録日2015-01-06
公開日2015-03-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献A tail of two sites: a bipartite mechanism for recognition of notch ligands by mind bomb e3 ligases.
Mol.Cell, 57, 2015
5UX6
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BU of 5ux6 by Molmil
Structure of Human POFUT1 in its apo form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GDP-fucose protein O-fucosyltransferase 1, GLYCEROL
著者Xu, X, McMillan, B, Blacklow, S.C.
登録日2017-02-22
公開日2017-04-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Structure of human POFUT1, its requirement in ligand-independent oncogenic Notch signaling, and functional effects of Dowling-Degos mutations.
Glycobiology, 27, 2017
5UXH
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BU of 5uxh by Molmil
Structure of Human POFUT1 in complex with GDP-fucose
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GDP-fucose protein O-fucosyltransferase 1, GUANOSINE-5'-DIPHOSPHATE-BETA-L-FUCOPYRANOSE
著者Xu, X, McMillan, B, Blacklow, S.C.
登録日2017-02-22
公開日2017-04-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Structure of human POFUT1, its requirement in ligand-independent oncogenic Notch signaling, and functional effects of Dowling-Degos mutations.
Glycobiology, 27, 2017
2OO9
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BU of 2oo9 by Molmil
crystal structure of the UBA domain from human c-Cbl ubiquitin ligase
分子名称: E3 ubiquitin-protein ligase CBL
著者Kozlov, G, Gehring, K.
登録日2007-01-25
公開日2007-02-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for UBA-mediated dimerization of c-Cbl ubiquitin ligase.
J.Biol.Chem., 282, 2007
3ZU7
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BU of 3zu7 by Molmil
Crystal structure of a designed selected Ankyrin Repeat protein in complex with the MAP kinase ERK2
分子名称: DESIGNED ANKYRIN REPEAT PROTEIN, MITOGEN-ACTIVATED PROTEIN KINASE 1
著者Kummer, L, Mittl, P.R, Pluckthun, A.
登録日2011-07-16
公開日2012-06-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structural and Functional Analysis of Phosphorylation-Specific Binders of the Kinase Erk from Designed Ankyrin Repeat Protein Libraries.
Proc.Natl.Acad.Sci.USA, 109, 2012
3ZUV
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BU of 3zuv by Molmil
Crystal structure of a designed selected Ankyrin Repeat protein in complex with the phosphorylated MAP kinase ERK2
分子名称: DESIGNED ANKYRIN REPEAT PROTEIN, MITOGEN-ACTIVATED PROTEIN KINASE 1, SULFATE ION
著者Kummer, L, Mittl, P.R, Pluckthun, A.
登録日2011-07-20
公開日2012-06-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Structural and Functional Analysis of Phosphorylation-Specific Binders of the Kinase Erk from Designed Ankyrin Repeat Protein Libraries.
Proc.Natl.Acad.Sci.USA, 109, 2012
4C58
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BU of 4c58 by Molmil
Structure of GAK kinase in complex with nanobody (NbGAK_4)
分子名称: 1,2-ETHANEDIOL, 9-HYDROXY-4-PHENYLPYRROLO[3,4-C]CARBAZOLE-1,3(2H,6H)-DIONE, Cyclin-G-associated kinase, ...
著者Chaikuad, A, Keates, T, Allerston, C.K, Gileadi, O, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Muller-Knapp, S.
登録日2013-09-10
公開日2013-10-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Structure of cyclin G-associated kinase (GAK) trapped in different conformations using nanobodies.
Biochem. J., 459, 2014
4C59
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BU of 4c59 by Molmil
Structure of GAK kinase in complex with nanobody (NbGAK_4)
分子名称: (2Z,3E)-2,3'-BIINDOLE-2',3(1H,1'H)-DIONE 3-{O-[(3R)-3,4-DIHYDROXYBUTYL]OXIME}, Cyclin-G-associated kinase, NANOBODY
著者Chaikuad, A, Keates, T, Allerston, C.K, Gileadi, O, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Muller-Knapp, S.
登録日2013-09-10
公開日2013-10-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of cyclin G-associated kinase (GAK) trapped in different conformations using nanobodies.
Biochem. J., 459, 2014
4C57
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BU of 4c57 by Molmil
Structure of GAK kinase in complex with a nanobody
分子名称: (2Z,3E)-2,3'-BIINDOLE-2',3(1H,1'H)-DIONE 3-{O-[(3R)-3,4-DIHYDROXYBUTYL]OXIME}, 1,2-ETHANEDIOL, Cyclin-G-associated kinase, ...
著者Chaikuad, A, Keates, T, Krojer, T, Allerston, C.K, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Muller-Knapp, S.
登録日2013-09-10
公開日2013-10-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structure of Cyclin G-Associated Kinase (Gak) Trapped in Different Conformations Using Nanobodies.
Biochem.J., 459, 2014

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