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1BVH
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BU of 1bvh by Molmil
SOLUTION STRUCTURE OF A LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE
分子名称: ACID PHOSPHATASE
著者Logan, T.M, Zhou, M.-M, Nettesheim, D.G, Meadows, R.P, Van Etten, R.L, Fesik, S.W.
登録日1994-05-03
公開日1994-07-31
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of a low molecular weight protein tyrosine phosphatase.
Biochemistry, 33, 1994
1JM4
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BU of 1jm4 by Molmil
NMR Structure of P/CAF Bromodomain in Complex with HIV-1 Tat Peptide
分子名称: HIV-1 Tat Peptide, P300/CBP-associated Factor
著者Mujtaba, S, He, Y, Zeng, L, Farooq, A, Carlson, J.E, Ott, M, Verdin, E, Zhou, M.-M.
登録日2001-07-17
公開日2002-07-17
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Structural basis of lysine-acetylated HIV-1 Tat recognition by PCAF bromodomain
Mol.Cell, 9, 2002
1XR0
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BU of 1xr0 by Molmil
Structural Basis of SNT PTB Domain Interactions with Distinct Neurotrophic Receptors
分子名称: Basic fibroblast growth factor receptor 1, FGFR signalling adaptor SNT-1
著者Dhalluin, C, Yan, K.S, Plotnikova, O, Lee, K.W, Zeng, L, Kuti, M, Mujtaba, S, Goldfarb, M.P, Zhou, M.-M.
登録日2004-10-13
公開日2004-11-02
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural Basis of SNT PTB Domain Interactions with Distinct Neurotrophic Receptors
Mol.Cell, 6, 2000
2AQE
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BU of 2aqe by Molmil
Structural and functional analysis of ada2 alpha swirm domain
分子名称: Transcriptional adaptor 2, Ada2 alpha
著者Qian, C, Zhang, Q, Zeng, L, Zhou, M.-M.
登録日2005-08-17
公開日2005-12-13
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure and chromosomal DNA binding of the SWIRM domain
Nat.Struct.Mol.Biol., 12, 2005
1R4K
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BU of 1r4k by Molmil
Solution Structure of the Drosophila Argonaute 1 PAZ Domain
分子名称: Argonaute 1
著者Yan, K.S, Yan, S, Farooq, A, Han, A, Zeng, L, Zhou, M.-M.
登録日2003-10-07
公開日2003-12-09
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure and conserved RNA binding of the PAZ domain
Nature, 426, 2003
1N3H
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BU of 1n3h by Molmil
Coupling of Folding and Binding in the PTB Domain of the Signaling Protein Shc
分子名称: SHC Transforming protein
著者Farooq, A, Zeng, L, Yan, K.S, Ravichandran, K.S, Zhou, M.-M.
登録日2002-10-28
公開日2003-10-28
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Coupling of Folding and Binding in the PTB Domain of the Signaling Protein Shc
Structure, 11, 2003
1N72
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BU of 1n72 by Molmil
Structure and Ligand of a Histone Acetyltransferase Bromodomain
分子名称: HISTONE ACETYLTRANSFERASE
著者Dhalluin, C, Carlson, J.E, Zeng, L, He, C, Aggarwal, A.K, Zhou, M.-M.
登録日2002-11-12
公開日2002-12-11
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure and Ligand of a Histone Acetyltransferase Bromodomain
Nature, 399, 1999
1OP4
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BU of 1op4 by Molmil
Solution Structure of Neural Cadherin Prodomain
分子名称: Neural-cadherin
著者Koch, A.W, Farooq, A, Shan, W, Zeng, L, Colman, D.R, Zhou, M.-M.
登録日2003-03-04
公開日2004-03-16
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Structure of the Neural (N-) Cadherin Prodomain Reveals a Cadherin Extracellular Domain-like Fold without Adhesive Characteristics
Structure, 12, 2004
1M3G
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BU of 1m3g by Molmil
SOLUTION STRUCTURE OF THE CATALYTIC DOMAIN OF MAPK PHOSPHATASE PAC-1: INSIGHTS INTO SUBSTRATE-INDUCED ENZYMATIC ACTIVATION
分子名称: DUAL SPECIFICITY PROTEIN PHOSPHATASE 2
著者Farooq, A, Zhou, M.-M.
登録日2002-06-27
公開日2003-06-27
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution Structure of the MAPK Phosphatase PAC-1 Catalytic Domain Insights into Substrate-Induced Enzymatic Activation of MKP
Structure, 11, 2003
1N3J
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BU of 1n3j by Molmil
Structure and Substrate of a Histone H3 Lysine Methyltransferase from Paramecium Bursaria Chlorella Virus 1
分子名称: Histone H3 Lysine Methyltransferase
著者Manzur, K.L, Farooq, A, Zeng, L, Plotnikova, O, Sachchidanand, Koch, A.W, Zhou, M.-M.
登録日2002-10-28
公開日2003-01-28
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A dimeric viral SET domain methyltransferase specific to Lys27 of histone H3.
Nat.Struct.Biol., 10, 2003
1OY2
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BU of 1oy2 by Molmil
Coupling of Folding and Binding in the PTB Domain of the Signaling Protein Shc
分子名称: SHC transforming protein
著者Farooq, A, Zeng, L, Yan, K.S, Ravichandran, K.S, Zhou, M.-M.
登録日2003-04-03
公開日2004-04-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Coupling of Folding and Binding in the PTB Domain of the Signaling Protein Shc
Structure, 11, 2003
7XEZ
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BU of 7xez by Molmil
NMR solution structures of p300 TAZ2 domain in complex with BRD4-NUT F1c domain binding motif #2
分子名称: Histone acetyltransferase p300,NUT family member 1, ZINC ION
著者Yu, D, Zeng, L, Zhou, M.-M.
登録日2022-03-31
公開日2023-04-12
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Mechanism of BRD4-NUT Fusion Protein in p300-Activated Hyperacetylation
To Be Published
7XFG
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BU of 7xfg by Molmil
NMR solution structures of p300 TAZ2 domain in complex with BRD4-NUT F1c domain binding motif #1
分子名称: Histone acetyltransferase p300, NUT family member 1, ZINC ION
著者Yu, D, Zeng, L, Zhou, M.-M.
登録日2022-04-01
公開日2023-04-12
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Mechanism of BRD4-NUT Fusion Protein in p300-Activated Hyperacetylation
To Be Published
4NUC
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BU of 4nuc by Molmil
Crystal structure of the first bromodomain of human BRD4 in complex with MS435 inhibitor
分子名称: 1,2-ETHANEDIOL, 4-[(E)-(4-hydroxy-3,5-dimethylphenyl)diazenyl]-N-(pyridin-2-yl)benzenesulfonamide, Bromodomain-containing protein 4
著者Plotnikov, A.N, Joshua, J, Zhou, M.-M.
登録日2013-12-03
公開日2014-04-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure-Guided Design of Potent Diazobenzene Inhibitors for the BET Bromodomains
J.Med.Chem., 56, 2013
4NUE
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BU of 4nue by Molmil
Crystal structure of the first bromodomain of human BRD4 in complex with MS267 inhibitor
分子名称: 1,2-ETHANEDIOL, 4-[(E)-(2-amino-4-hydroxy-3,5-dimethylphenyl)diazenyl]-N-(pyridin-2-yl)benzenesulfonamide, Bromodomain-containing protein 4
著者Plotnikov, A.N, Joshua, J, Zhou, M.-M.
登録日2013-12-03
公開日2014-04-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structure-Guided Design of Potent Diazobenzene Inhibitors for the BET Bromodomains
J.Med.Chem., 56, 2013
4NUD
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BU of 4nud by Molmil
Crystal structure of the first bromodomain of human BRD4 in complex with MS436 inhibitor
分子名称: 1,2-ETHANEDIOL, 4-[(E)-(2-amino-4-hydroxy-5-methylphenyl)diazenyl]-N-(pyridin-2-yl)benzenesulfonamide, Bromodomain-containing protein 4
著者Plotnikov, A.N, Joshua, J, Zhou, M.-M.
登録日2013-12-03
公開日2014-04-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structure-Guided Design of Potent Diazobenzene Inhibitors for the BET Bromodomains
J.Med.Chem., 56, 2013
1SHC
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BU of 1shc by Molmil
SHC PTB DOMAIN COMPLEXED WITH A TRKA RECEPTOR PHOSPHOPEPTIDE, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: SHC, TRKA RECEPTOR PHOSPHOPEPTIDE
著者Zhou, M.-M, Ravichandran, K.S, Olejniczak, E.T, Petros, A.M, Meadows, R.P, Sattler, M, Harlan, J.E, Wade, W.S, Burakoff, S.J, Fesik, S.W.
登録日1996-03-27
公開日1997-05-15
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Structure and ligand recognition of the phosphotyrosine binding domain of Shc.
Nature, 378, 1995
1TCE
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BU of 1tce by Molmil
SOLUTION NMR STRUCTURE OF THE SHC SH2 DOMAIN COMPLEXED WITH A TYROSINE-PHOSPHORYLATED PEPTIDE FROM THE T-CELL RECEPTOR, MINIMIZED AVERAGE STRUCTURE
分子名称: PHOSPHOPEPTIDE OF THE ZETA CHAIN OF T CELL RECEPTOR, SHC
著者Zhou, M.-M, Meadows, R.P, Logan, T.M, Yoon, H.S, Wade, W.R, Ravichandran, K.S, Burakoff, S.J, Feisk, S.W.
登録日1996-03-27
公開日1997-05-15
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Solution structure of the Shc SH2 domain complexed with a tyrosine-phosphorylated peptide from the T-cell receptor.
Proc.Natl.Acad.Sci.USA, 92, 1995
1IRS
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BU of 1irs by Molmil
IRS-1 PTB DOMAIN COMPLEXED WITH A IL-4 RECEPTOR PHOSPHOPEPTIDE, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: IL-4 RECEPTOR PHOSPHOPEPTIDE, IRS-1
著者Zhou, M.-M, Huang, B, Olejniczak, E.T, Meadows, R.P, Shuker, S.B, Miyazaki, M, Trub, T, Shoelson, S.E, Feisk, S.W.
登録日1996-03-22
公開日1997-05-15
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Structural basis for IL-4 receptor phosphopeptide recognition by the IRS-1 PTB domain.
Nat.Struct.Biol., 3, 1996
2LSP
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BU of 2lsp by Molmil
solution structures of BRD4 second bromodomain with NF-kB-K310ac peptide
分子名称: Bromodomain-containing protein 4, NF-kB-K310ac peptide
著者Zhang, G, Liu, R, Zhong, Y, Plotnikov, A.N, Zhang, W, Rusinova, E, Gerona-Nevarro, G, Moshkina, N, Joshua, J, Chuang, P.Y, Ohlmeyer, M, He, J, Zhou, M.-M.
登録日2012-05-03
公開日2012-07-18
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Down-regulation of NF-kappa B transcriptional activity in HIV-associated kidney disease by BRD4 inhibition.
J.Biol.Chem., 287, 2012
4F3I
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BU of 4f3i by Molmil
Crystal structure of the first bromodomain of human BRD4 in complex with MS417 inhibitor
分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, methyl [(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetate
著者Joshua, J, Zhou, M.-M, Plotnikov, A.N.
登録日2012-05-09
公開日2012-09-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Down-regulation of NF-{kappa}B Transcriptional Activity in HIV-associated Kidney Disease by BRD4 Inhibition.
J.Biol.Chem., 287, 2012
6BNH
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BU of 6bnh by Molmil
Solution NMR structures of BRD4 ET domain with JMJD6 peptide
分子名称: Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, Bromodomain-containing protein 4
著者Konuma, T, Yu, D, Zhao, C, Ju, Y, Sharma, R, Ren, C, Zhang, Q, Zhou, M.-M, Zeng, L.
登録日2017-11-16
公開日2017-12-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Mechanism of the Oxygenase JMJD6 Recognition by the Extraterminal (ET) Domain of BRD4.
Sci Rep, 7, 2017
2AQF
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BU of 2aqf by Molmil
Structural and functional analysis of ADA2 alpha swirm domain
分子名称: transcriptional adaptor 2, Ada2 alpha
著者Qian, C, Zhang, Q, Zhou, M.-M, Zeng, L.
登録日2005-08-17
公開日2006-01-31
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure and chromosomal DNA binding of the SWIRM domain.
Nat.Struct.Mol.Biol., 12, 2005
3QB8
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BU of 3qb8 by Molmil
Paramecium Chlorella Bursaria Virus1 Putative ORF A654L is a Polyamine Acetyltransferase
分子名称: A654L protein, COENZYME A, IMIDAZOLE
著者Charlop-Powers, Z, Zhou, M.-M, Jakoncic, J, Gurnon, J, Van Etten, J.
登録日2011-01-12
公開日2012-01-25
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Paramecium bursaria chlorella virus 1 encodes a polyamine acetyltransferase.
J. Biol. Chem., 287, 2012
1HZM
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BU of 1hzm by Molmil
STRUCTURE OF ERK2 BINDING DOMAIN OF MAPK PHOSPHATASE MKP-3: STRUCTURAL INSIGHTS INTO MKP-3 ACTIVATION BY ERK2
分子名称: DUAL SPECIFICITY PROTEIN PHOSPHATASE 6
著者Farooq, A, Zhou, M.-M.
登録日2001-01-25
公開日2002-01-25
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of ERK2 binding domain of MAPK phosphatase MKP-3: structural insights into MKP-3 activation by ERK2.
Mol.Cell, 7, 2001

 

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