8HKK
| ion channel | 分子名称: | POTASSIUM ION, Potassium channel subfamily T member 1, SODIUM ION, ... | 著者 | Jiang, D.H, Zhang, J.T. | 登録日 | 2022-11-27 | 公開日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (2.84 Å) | 主引用文献 | Structural basis of human Slo2.2 channel gating and modulation. Cell Rep, 42, 2023
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8HKF
| ion channel | 分子名称: | POTASSIUM ION, Potassium channel subfamily T member 1, ZINC ION | 著者 | Jiang, D.H, Zhang, Z.T. | 登録日 | 2022-11-25 | 公開日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (2.66 Å) | 主引用文献 | Structural basis of human Slo2.2 channel gating and modulation. Cell Rep, 42, 2023
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8HKM
| ion channel | 分子名称: | POTASSIUM ION, Potassium channel subfamily T member 1, ZINC ION, ... | 著者 | Jiang, D.H, Zhang, J.T. | 登録日 | 2022-11-27 | 公開日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | 主引用文献 | Structural basis of human Slo2.2 channel gating and modulation. Cell Rep, 42, 2023
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8HIR
| potassium channels | 分子名称: | POTASSIUM ION, Potassium channel subfamily T member 1, SODIUM ION, ... | 著者 | Jiang, D.H, Zhang, J.T. | 登録日 | 2022-11-21 | 公開日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | 主引用文献 | Structural basis of human Slo2.2 channel gating and modulation. Cell Rep, 42, 2023
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8HKQ
| ion channel | 分子名称: | POTASSIUM ION, Potassium channel subfamily T member 1, SODIUM ION, ... | 著者 | Jiang, D.H, Zhang, J.T. | 登録日 | 2022-11-27 | 公開日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural basis of human Slo2.2 channel gating and modulation. Cell Rep, 42, 2023
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8JTC
| Human VMAT2 complex with reserpine | 分子名称: | Synaptic vesicular amine transporter, reserpine | 著者 | Jiang, D.H, Wu, D. | 登録日 | 2023-06-21 | 公開日 | 2023-11-29 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.52 Å) | 主引用文献 | Transport and inhibition mechanisms of human VMAT2. Nature, 626, 2024
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8JTA
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8JSW
| Human VMAT2 complex with serotonin | 分子名称: | SEROTONIN, Synaptic vesicular amine transporter | 著者 | Jiang, D.H, Wu, D. | 登録日 | 2023-06-20 | 公開日 | 2023-11-29 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (2.84 Å) | 主引用文献 | Transport and inhibition mechanisms of human VMAT2. Nature, 626, 2024
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8JT9
| Human VMAT2 complex with ketanserin | 分子名称: | 3-[2-[4-(4-fluorophenyl)carbonylpiperidin-1-yl]ethyl]-1~{H}-quinazoline-2,4-dione, Synaptic vesicular amine transporter | 著者 | Jiang, D.H, Wu, D. | 登録日 | 2023-06-21 | 公開日 | 2023-11-29 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | 主引用文献 | Transport and inhibition mechanisms of human VMAT2. Nature, 626, 2024
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7EZM
| Cryo-EM structure of an activated Cholecystokinin A receptor (CCKAR)-Gq complex | 分子名称: | Cholecystokinin receptor type A, Cholecystokinin-8, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Liu, Q.F, Yang, D.H, Zhuang, Y.W, Croll, T.I, Cai, X.Q, Duan, J, Dai, A.T, Yin, W.C, Ye, C.Y, Zhou, F.L, Wu, B.L, Zhao, Q, Xu, H.E, Wang, M.W, Jiang, Y. | 登録日 | 2021-06-01 | 公開日 | 2021-08-25 | 最終更新日 | 2022-06-29 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Ligand recognition and G-protein coupling selectivity of cholecystokinin A receptor Nat.Chem.Biol., 17, 2021
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7EZH
| Cryo-EM structure of an activated Cholecystokinin A receptor (CCKAR)-Gi complex | 分子名称: | Cholecystokinin receptor type A, Cholecystokinin-8, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Liu, Q.F, Yang, D.H, Zhuang, Y.W, Croll, T.I, Cai, X.Q, Duan, J, Dai, A.T, Yin, W.C, Ye, C.Y, Zhou, F.L, Wu, B.L, Zhao, Q, Xu, H.E, Wang, M.W, Jiang, Y. | 登録日 | 2021-06-01 | 公開日 | 2021-08-25 | 最終更新日 | 2022-06-29 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Ligand recognition and G-protein coupling selectivity of cholecystokinin A receptor Nat.Chem.Biol., 17, 2021
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7EZK
| Cryo-EM structure of an activated Cholecystokinin A receptor (CCKAR)-Gs complex | 分子名称: | Chimera of Guanine nucleotide-binding protein G(i) subunit alpha-1 and Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Cholecystokinin receptor type A, Cholecystokinin-8, ... | 著者 | Liu, Q.F, Yang, D.H, Zhuang, Y.W, Croll, T.I, Cai, X.Q, Duan, J, Dai, A.T, Yin, W.C, Ye, C.Y, Zhou, F.L, Wu, B.L, Zhao, Q, Xu, H.E, Wang, M.W, Jiang, Y. | 登録日 | 2021-06-01 | 公開日 | 2021-08-25 | 最終更新日 | 2022-06-29 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Ligand recognition and G-protein coupling selectivity of cholecystokinin A receptor Nat.Chem.Biol., 17, 2021
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7UL1
| Crystal structure of SARS-CoV-2 RBD in complex with the neutralizing IGHV3-53-encoded antibody EH3 isolated from a nonvaccinated pediatric patient | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of EH3, Light chain of EH3, ... | 著者 | Chen, Y, Tolbert, W.D, Pazgier, M. | 登録日 | 2022-04-03 | 公開日 | 2023-03-08 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Molecular basis for antiviral activity of two pediatric neutralizing antibodies targeting SARS-CoV-2 Spike RBD. Iscience, 26, 2023
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7UL0
| Crystal structure of SARS-CoV-2 RBD in complex with the ridge-binding nAb EH8 isolated from a nonvaccinated pediatric patient | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of EH8, ... | 著者 | Chen, Y, Tolbert, W.D, Bai, X, Pazgier, M. | 登録日 | 2022-04-03 | 公開日 | 2023-03-08 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Molecular basis for antiviral activity of two pediatric neutralizing antibodies targeting SARS-CoV-2 Spike RBD. Iscience, 26, 2023
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7W4X
| Crystal structure of PDE4D catalytic domain complexed with 17 | 分子名称: | (2R,4S)-2-(2-hydroxyethyl)-2,6-dimethyl-4-(2-methylprop-1-enyl)-3,4-dihydropyrano[3,2-c][1,8]naphthyridin-5-one, MAGNESIUM ION, ZINC ION, ... | 著者 | Huang, Y.-Y, Luo, H.-B. | 登録日 | 2021-11-29 | 公開日 | 2022-03-16 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.20007324 Å) | 主引用文献 | Discovery and Structural Optimization of Toddacoumalone Derivatives as Novel PDE4 Inhibitors for the Topical Treatment of Psoriasis. J.Med.Chem., 65, 2022
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7W4Y
| Crystal structure of PDE4D catalytic domain complexed with 33a | 分子名称: | (2R,4S)-6-ethyl-2-(2-hydroxyethyl)-2,8-dimethyl-4-(2-methylprop-1-enyl)-3,4-dihydropyrano[3,2-c][1,8]naphthyridin-5-one, MAGNESIUM ION, ZINC ION, ... | 著者 | Huang, Y.-Y, Luo, H.-B. | 登録日 | 2021-11-29 | 公開日 | 2022-03-16 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.10002947 Å) | 主引用文献 | Discovery and Structural Optimization of Toddacoumalone Derivatives as Novel PDE4 Inhibitors for the Topical Treatment of Psoriasis. J.Med.Chem., 65, 2022
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7X5H
| Serotonin 5A (5-HT5A) receptor-Gi protein complex | 分子名称: | 3-(2-azanylethyl)-1H-indole-5-carboxamide, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Tan, Y, Xu, P, Huang, S, Xu, H.E, Jiang, Y. | 登録日 | 2022-03-04 | 公開日 | 2022-09-14 | 最終更新日 | 2022-09-21 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural insights into the ligand binding and G i coupling of serotonin receptor 5-HT 5A . Cell Discov, 8, 2022
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7EIB
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7F2O
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7FD2
| Cryo-EM structure of an alphavirus, Getah virus | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Liu, Z, Liu, C, Wang, A. | 登録日 | 2021-07-15 | 公開日 | 2022-08-10 | 実験手法 | ELECTRON MICROSCOPY (2.81 Å) | 主引用文献 | Structure of infective Getah virus at 2.8 angstrom resolution determined by cryo-electron microscopy. Cell Discov, 8, 2022
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