7EZM
Cryo-EM structure of an activated Cholecystokinin A receptor (CCKAR)-Gq complex
Summary for 7EZM
Entry DOI | 10.2210/pdb7ezm/pdb |
Related | 7EZH 7EZK |
EMDB information | 31387 31388 31389 |
Descriptor | fusion protein of Guanine nucleotide-binding protein G(i) subunit alpha-1 and Guanine nucleotide-binding protein G(q) subunit alpha-q, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Cholecystokinin receptor type A, ... (6 entities in total) |
Functional Keywords | cholecystokinin a receptor, gq complex, cck-8, membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 163329.21 |
Authors | Liu, Q.F.,Yang, D.H.,Zhuang, Y.W.,Croll, T.I.,Cai, X.Q.,Duan, J.,Dai, A.T.,Yin, W.C.,Ye, C.Y.,Zhou, F.L.,Wu, B.L.,Zhao, Q.,Xu, H.E.,Wang, M.W.,Jiang, Y. (deposition date: 2021-06-01, release date: 2021-08-25, Last modification date: 2022-06-29) |
Primary citation | Liu, Q.,Yang, D.,Zhuang, Y.,Croll, T.I.,Cai, X.,Dai, A.,He, X.,Duan, J.,Yin, W.,Ye, C.,Zhou, F.,Wu, B.,Zhao, Q.,Xu, H.E.,Wang, M.W.,Jiang, Y. Ligand recognition and G-protein coupling selectivity of cholecystokinin A receptor Nat.Chem.Biol., 17:1238-1244, 2021 Cited by DOI: 10.1038/s41589-021-00841-3PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.9 Å) |
Structure validation
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