7UL1
Crystal structure of SARS-CoV-2 RBD in complex with the neutralizing IGHV3-53-encoded antibody EH3 isolated from a nonvaccinated pediatric patient
Summary for 7UL1
Entry DOI | 10.2210/pdb7ul1/pdb |
Related | 7UL0 |
Descriptor | Spike protein S1, Heavy chain of EH3, Light chain of EH3, ... (5 entities in total) |
Functional Keywords | pediatric neutralizing mab, ighv3-53 ab, , class-1 rbd-binding antibody, viral protein, viral protein-immune system complex, viral protein/immune system |
Biological source | Severe acute respiratory syndrome coronavirus More |
Total number of polymer chains | 3 |
Total formula weight | 70377.66 |
Authors | Chen, Y.,Tolbert, W.D.,Pazgier, M. (deposition date: 2022-04-03, release date: 2023-03-08, Last modification date: 2023-10-25) |
Primary citation | Chen, Y.,Prevost, J.,Ullah, I.,Romero, H.,Lisi, V.,Tolbert, W.D.,Grover, J.R.,Ding, S.,Gong, S.Y.,Beaudoin-Bussieres, G.,Gasser, R.,Benlarbi, M.,Vezina, D.,Anand, S.P.,Chatterjee, D.,Goyette, G.,Grunst, M.W.,Yang, Z.,Bo, Y.,Zhou, F.,Beland, K.,Bai, X.,Zeher, A.R.,Huang, R.K.,Nguyen, D.N.,Sherburn, R.,Wu, D.,Piszczek, G.,Pare, B.,Matthies, D.,Xia, D.,Richard, J.,Kumar, P.,Mothes, W.,Cote, M.,Uchil, P.D.,Lavallee, V.P.,Smith, M.A.,Pazgier, M.,Haddad, E.,Finzi, A. Molecular basis for antiviral activity of two pediatric neutralizing antibodies targeting SARS-CoV-2 Spike RBD. Iscience, 26:105783-105783, 2023 Cited by PubMed: 36514310DOI: 10.1016/j.isci.2022.105783 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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