5TTE
| Crystal Structure of an RBR E3 ubiquitin ligase in complex with an E2-Ub thioester intermediate mimic | 分子名称: | E3 ubiquitin-protein ligase ARIH1, Ubiquitin-conjugating enzyme E2 L3, ZINC ION, ... | 著者 | Yuan, L, Lv, Z, Olsen, S.K. | 登録日 | 2016-11-03 | 公開日 | 2017-08-23 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.501 Å) | 主引用文献 | Structural insights into the mechanism and E2 specificity of the RBR E3 ubiquitin ligase HHARI. Nat Commun, 8, 2017
|
|
7K5J
| Structure of an E1-E2-ubiquitin thioester mimetic | 分子名称: | ADENOSINE MONOPHOSPHATE, Ubiquitin, Ubiquitin-activating enzyme E1 1, ... | 著者 | Yuan, L, Lv, Z, Olsen, S.K. | 登録日 | 2020-09-16 | 公開日 | 2021-04-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.42 Å) | 主引用文献 | Crystal structures of an E1-E2-ubiquitin thioester mimetic reveal molecular mechanisms of transthioesterification. Nat Commun, 12, 2021
|
|
8ISS
| Cryo-EM structure of wild-type human tRNA Splicing Endonuclease Complex bound to pre-tRNA-ARG at 3.19 A resolution | 分子名称: | MAGNESIUM ION, RNA (88-MER), tRNA-splicing endonuclease subunit Sen15, ... | 著者 | Sun, Y, Zhang, Y, Yuan, L, Han, Y. | 登録日 | 2023-03-21 | 公開日 | 2023-10-18 | 実験手法 | ELECTRON MICROSCOPY (3.19 Å) | 主引用文献 | Recognition and cleavage mechanism of intron-containing pre-tRNA by human TSEN endonuclease complex. Nat Commun, 14, 2023
|
|
5KNL
| Crystal structure of S. pombe ubiquitin E1 (Uba1) in complex with Ubc15 and ubiquitin | 分子名称: | SULFATE ION, Ubiquitin, Ubiquitin-activating enzyme E1 1, ... | 著者 | Olsen, S.K, Lv, Z, Yuan, L, Williams, K. | 登録日 | 2016-06-28 | 公開日 | 2017-02-15 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | S. pombe Uba1-Ubc15 Structure Reveals a Novel Regulatory Mechanism of Ubiquitin E2 Activity. Mol. Cell, 65, 2017
|
|
6CWZ
| Crystal structure of apo SUMO E1 | 分子名称: | SUMO-activating enzyme subunit 1, SUMO-activating enzyme subunit 2, ZINC ION | 著者 | Lv, Z, Yuan, L, Atkison, J.H, Williams, K.M, Olsen, S.K. | 登録日 | 2018-04-01 | 公開日 | 2019-01-16 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Molecular mechanism of a covalent allosteric inhibitor of SUMO E1 activating enzyme. Nat Commun, 9, 2018
|
|
6DC6
| Crystal structure of human ubiquitin activating enzyme E1 (Uba1) in complex with ubiquitin | 分子名称: | MAGNESIUM ION, PYROPHOSPHATE 2-, Ubiquitin, ... | 著者 | Lv, Z, Yuan, L, Williams, K.M, Atkison, J.H, Olsen, S.K. | 登録日 | 2018-05-04 | 公開日 | 2018-10-10 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.14 Å) | 主引用文献 | Crystal structure of a human ubiquitin E1-ubiquitin complex reveals conserved functional elements essential for activity. J. Biol. Chem., 293, 2018
|
|
5UM6
| Crystal Structure of S. pombe Uba1 in a closed conformation | 分子名称: | 2-(decylamino)ethane-1-thiol, N-(2-{[(4-chlorophenyl)methyl]disulfanyl}ethyl)decan-1-amine, SULFATE ION, ... | 著者 | Lv, Z, Yuan, L, Aldana-Masangkay, G, Atkison, J.H, Chen, Y, Olsen, S.K. | 登録日 | 2017-01-26 | 公開日 | 2017-06-14 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.794 Å) | 主引用文献 | Domain alternation and active site remodeling are conserved structural features of ubiquitin E1. J. Biol. Chem., 292, 2017
|
|
4J0U
| Crystal structure of IFIT5/ISG58 | 分子名称: | Interferon-induced protein with tetratricopeptide repeats 5 | 著者 | Liu, Y, Liang, H, Feng, F, Yuan, L, Wang, Y.E, Crowley, C, Lv, Z, Li, J, Zeng, S, Cheng, G. | 登録日 | 2013-01-31 | 公開日 | 2013-02-13 | 実験手法 | X-RAY DIFFRACTION (1.969 Å) | 主引用文献 | Crystal Structure of IFIT5 To be Published
|
|
6CWY
| Crystal structure of SUMO E1 in complex with an allosteric inhibitor | 分子名称: | GLYCEROL, MAGNESIUM ION, SULFATE ION, ... | 著者 | Lv, Z, Yuan, L, Atkison, J.H, Williams, K.M, Olsen, S.K. | 登録日 | 2018-04-01 | 公開日 | 2019-01-16 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.462 Å) | 主引用文献 | Molecular mechanism of a covalent allosteric inhibitor of SUMO E1 activating enzyme. Nat Commun, 9, 2018
|
|
8IGT
| Crystal Structure of Intracellular B30.2 Domain of BTN2A1 | 分子名称: | Butyrophilin subfamily 2 member A1, ZINC ION | 著者 | Yuan, L.J, Yang, Y.Y, Li, X, Cai, N.N, Chen, C.C, Guo, R.T, Zhang, Y.H. | 登録日 | 2023-02-21 | 公開日 | 2023-09-13 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate V gamma 9V delta 2 T cells. Nature, 621, 2023
|
|
8JYE
| Crystal Structure of Intracellular B30.2 Domain of BTN3A1 and BTN2A1 in Complex with HMBPP | 分子名称: | (2E)-4-hydroxy-3-methylbut-2-en-1-yl trihydrogen diphosphate, 1,2-ETHANEDIOL, Butyrophilin subfamily 2 member A1, ... | 著者 | Yuan, L.J, Yang, Y.Y, Li, X, Cai, N.N, Chen, C.-C, Guo, R.-T, Zhang, Y.H. | 登録日 | 2023-07-03 | 公開日 | 2023-09-13 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate V gamma 9V delta 2 T cells. Nature, 621, 2023
|
|
8JYC
| Crystal Structure of Intracellular B30.2 Domain of BTN3A1 and BTN2A1 in Complex with DMAPP | 分子名称: | 1,2-ETHANEDIOL, Butyrophilin subfamily 2 member A1, Butyrophilin subfamily 3 member A1, ... | 著者 | Yuan, L.J, Yang, Y.Y, Li, X, Cai, N.N, Chen, C.-C, Guo, R.-T, Zhang, Y.H. | 登録日 | 2023-07-03 | 公開日 | 2023-09-13 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate V gamma 9V delta 2 T cells. Nature, 621, 2023
|
|
7SOL
| Crystal Structures of the bispecific ubiquitin/FAT10 activating enzyme, Uba6 | 分子名称: | ADENOSINE MONOPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, Ubiquitin, ... | 著者 | Olsen, S.K, Gao, F, Lv, Z. | 登録日 | 2021-10-31 | 公開日 | 2022-11-02 | 最終更新日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (2.25000644 Å) | 主引用文献 | Crystal structures reveal catalytic and regulatory mechanisms of the dual-specificity ubiquitin/FAT10 E1 enzyme Uba6. Nat Commun, 13, 2022
|
|
8HJT
| Crystal Structure of Intracellular B30.2 Domain of VpBTN3 and VpBTN2 in Complex with HMBPP | 分子名称: | (2E)-4-hydroxy-3-methylbut-2-en-1-yl trihydrogen diphosphate, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Butyrophylin 3, ... | 著者 | Yang, Y.Y, Shen, P.P, Li, X, Yi, S.M, Zhang, M.T, Huang, J.-W, Chen, C.-C, Guo, R.-T. | 登録日 | 2022-11-23 | 公開日 | 2023-09-13 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | 主引用文献 | Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate V gamma 9V delta 2 T cells. Nature, 621, 2023
|
|
8IH4
| Crystal Structure of Intracellular B30.2 Domain of BTN2A2 Mutant | 分子名称: | Butyrophilin subfamily 2 member A2 | 著者 | Yang, Y.Y, Yi, S.M, Zhang, M.T, Chen, C.C, Guo, R.T, Zhang, Y.H. | 登録日 | 2023-02-22 | 公開日 | 2023-09-13 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate V gamma 9V delta 2 T cells. Nature, 621, 2023
|
|
8IZE
| Crystal structure of intracellular B30.2 domain of BTN3A1 in complex with 4-HMBPP | 分子名称: | Butyrophilin subfamily 3 member A1, DI(HYDROXYETHYL)ETHER, [(E)-3-(hydroxymethyl)pent-2-enyl] phosphono hydrogen phosphate | 著者 | Yang, Y.Y, Yi, S.M, Huang, J.W, Chen, C.C, Guo, R.T. | 登録日 | 2023-04-07 | 公開日 | 2023-09-13 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate V gamma 9V delta 2 T cells. Nature, 621, 2023
|
|
8IZG
| Crystal structure of intracellular B30.2 domain of BTN3A1 in complex with 5-HMBPP | 分子名称: | 1,2-ETHANEDIOL, Butyrophilin subfamily 3 member A1, DI(HYDROXYETHYL)ETHER, ... | 著者 | Yang, Y.Y, Yi, S.M, Huang, J.W, Chen, C.C, Guo, R.T. | 登録日 | 2023-04-07 | 公開日 | 2023-09-13 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate V gamma 9V delta 2 T cells. Nature, 621, 2023
|
|
8IXV
| Crystal structure of intracellular B30.2 domain of BTN3A in complex with 2Cl-HMBPP | 分子名称: | 1,2-ETHANEDIOL, Butyrophilin subfamily 3 member A1, DI(HYDROXYETHYL)ETHER, ... | 著者 | Yang, Y.Y, Yi, S.M, Huang, J.W, Chen, C.C, Guo, R.T. | 登録日 | 2023-04-03 | 公開日 | 2023-09-13 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate V gamma 9V delta 2 T cells. Nature, 621, 2023
|
|
8JYB
| Crystal Structure of Intracellular B30.2 Domain of VpBTN3 | 分子名称: | Butyrophylin 3, SULFATE ION | 著者 | Yang, Y.Y, Yi, S.M, Zhang, M.T, Huang, J.-W, Chen, C.-C, Guo, R.-T. | 登録日 | 2023-07-03 | 公開日 | 2023-09-13 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate V gamma 9V delta 2 T cells. Nature, 621, 2023
|
|
8JY9
| Crystal Structure of Intracellular B30.2 Domain of VpBTN3 in Complex with HMBPP | 分子名称: | (2E)-4-hydroxy-3-methylbut-2-en-1-yl trihydrogen diphosphate, Butyrophylin 3, SULFATE ION | 著者 | Yang, Y.Y, Yi, S.M, Zhang, M.T, Huang, J.-W, Chen, C.-C, Guo, R.-T. | 登録日 | 2023-07-03 | 公開日 | 2023-09-13 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate V gamma 9V delta 2 T cells. Nature, 621, 2023
|
|
8JYA
| Crystal Structure of Intracellular B30.2 Domain of VpBTN3 in Complex with IPP | 分子名称: | 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Butyrophylin 3, SULFATE ION | 著者 | Yang, Y.Y, Yi, S.M, Zhang, M.T, Huang, J.-W, Chen, C.-C, Guo, R.-T. | 登録日 | 2023-07-03 | 公開日 | 2023-09-13 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate V gamma 9V delta 2 T cells. Nature, 621, 2023
|
|
8JYF
| Crystal Structure of Intracellular B30.2 Domain of VpBTN3 in Complex with DMAPP | 分子名称: | Butyrophylin 3, DIMETHYLALLYL DIPHOSPHATE, SULFATE ION | 著者 | Yang, Y.Y, Yi, S.M, Zhang, M.T, Huang, J.-W, Chen, C.-C, Guo, R.-T. | 登録日 | 2023-07-03 | 公開日 | 2023-09-13 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate V gamma 9V delta 2 T cells. Nature, 621, 2023
|
|
5DH3
| Crystal structure of MST2 in complex with XMU-MP-1 | 分子名称: | 4-[(5,10-dimethyl-6-oxo-6,10-dihydro-5H-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]benzenesulfonamide, CHLORIDE ION, SULFATE ION, ... | 著者 | Kong, L.L, Yun, C.H. | 登録日 | 2015-08-29 | 公開日 | 2016-08-31 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.468 Å) | 主引用文献 | Pharmacological targeting of kinases MST1 and MST2 augments tissue repair and regeneration Sci Transl Med, 8, 2016
|
|
3J9B
| Electron cryo-microscopy of an RNA polymerase | 分子名称: | Polymerase, Polymerase basic protein 2, RNA (5'-R(*UP*UP*UP*UP*UP*A)-3'), ... | 著者 | Chang, S.H, Sun, D.P, Liang, H.H, Wang, J, Li, J, Guo, L, Wang, X.L, Guan, C.C, Boruah, B.M, Yuan, L.M, Feng, F, Yang, M.R, Wojdyla, J, Wang, J.W, Wang, M.T, Wang, H.W, Liu, Y.F. | 登録日 | 2014-12-16 | 公開日 | 2015-02-18 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Cryo-EM Structure of Influenza Virus RNA Polymerase Complex at 4.3 angstrom Resolution. Mol.Cell, 2015
|
|
4RZE
| Crystal Structure Analysis of the NUR77 Ligand Binding Domain, L437W,D594E mutant | 分子名称: | GLYCEROL, Nuclear receptor subfamily 4 group A member 1 | 著者 | Fengwei, L, Xuyang, T, Anzhong, L, Li, L, Yuan, L, Hangzi, C, Qiao, W, Tianwei, L. | 登録日 | 2014-12-21 | 公開日 | 2015-03-18 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation. Nat.Chem.Biol., 11, 2015
|
|