6XSR
 
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4U4F
 | | Structure of GluA2* in complex with partial agonist (S)-5-Nitrowillardiine | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(5-nitro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-L-alanine, ... | | 著者 | Yelshanskaya, M.V, Li, M, Sobolevsky, A.I. | | 登録日 | 2014-07-23 | | 公開日 | 2014-08-27 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (4.79 Å) | | 主引用文献 | Structure of an agonist-bound ionotropic glutamate receptor.
Science, 345, 2014
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4U4G
 | | Structure of GluA2* in complex with competitive antagonist ZK 200775 | | 分子名称: | Glutamate receptor 2, beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid | | 著者 | Yelshanskaya, M.V, Li, M, Sobolevsky, A.I. | | 登録日 | 2014-07-23 | | 公開日 | 2014-10-22 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (4.49 Å) | | 主引用文献 | Structure of an agonist-bound ionotropic glutamate receptor.
Science, 345, 2014
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7TNO
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7TNP
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7TNK
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7TNM
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7TNJ
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7TNL
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7TNN
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5L1H
 | | AMPA subtype ionotropic glutamate receptor GluA2 in complex with noncompetitive inhibitor GYKI53655 | | 分子名称: | (8R)-5-(4-aminophenyl)-N,8-dimethyl-8,9-dihydro-2H,7H-[1,3]dioxolo[4,5-h][2,3]benzodiazepine-7-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2 | | 著者 | Yelshanskaya, M.V, Singh, A.K, Sampson, J.M, Sobolevsky, A.I. | | 登録日 | 2016-07-29 | | 公開日 | 2016-10-19 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.801 Å) | | 主引用文献 | Structural Bases of Noncompetitive Inhibition of AMPA-Subtype Ionotropic Glutamate Receptors by Antiepileptic Drugs.
Neuron, 91, 2016
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5L1B
 | | AMPA subtype ionotropic glutamate receptor GluA2 in Apo state | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2,Glutamate receptor 2 | | 著者 | Yelshanskaya, M.V, Singh, A.K, Sampson, J.M, Sobolevsky, A.I. | | 登録日 | 2016-07-28 | | 公開日 | 2016-10-19 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (4 Å) | | 主引用文献 | Structural Bases of Noncompetitive Inhibition of AMPA-Subtype Ionotropic Glutamate Receptors by Antiepileptic Drugs.
Neuron, 91, 2016
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5L1F
 | | AMPA subtype ionotropic glutamate receptor GluA2 in complex with noncompetitive inhibitor Perampanel | | 分子名称: | 2-(6'-oxo-1'-phenyl[1',6'-dihydro[2,3'-bipyridine]]-5'-yl)benzonitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2 | | 著者 | Yelshanskaya, M.V, Singh, A.K, Sampson, J.M, Sobolevsky, A.I. | | 登録日 | 2016-07-29 | | 公開日 | 2016-10-19 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (4 Å) | | 主引用文献 | Structural Bases of Noncompetitive Inhibition of AMPA-Subtype Ionotropic Glutamate Receptors by Antiepileptic Drugs.
Neuron, 91, 2016
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5L1E
 | | AMPA subtype ionotropic glutamate receptor GluA2 in complex with noncompetitive inhibitor CP465022 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(2-chlorophenyl)-2-(2-{6-[(diethylamino)methyl]pyridin-2-yl}ethyl)-6-fluoroquinazolin-4(3H)-one, Glutamate receptor 2 | | 著者 | Yelshanskaya, M.V, Singh, A.K, Sampson, J.M, Sobolevsky, A.I. | | 登録日 | 2016-07-29 | | 公開日 | 2016-10-19 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (4.37 Å) | | 主引用文献 | Structural Bases of Noncompetitive Inhibition of AMPA-Subtype Ionotropic Glutamate Receptors by Antiepileptic Drugs.
Neuron, 91, 2016
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5L1G
 | | AMPA subtype ionotropic glutamate receptor GluA2 in complex with GYKI-Br | | 分子名称: | (8R)-5-(4-amino-3-bromophenyl)-N,8-dimethyl-8,9-dihydro-2H,7H-[1,3]dioxolo[4,5-h][2,3]benzodiazepine-7-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2 | | 著者 | Yelshanskaya, M.V, Singh, A.K, Sampson, J.M, Sobolevsky, A.I. | | 登録日 | 2016-07-29 | | 公開日 | 2016-10-19 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (4.507 Å) | | 主引用文献 | Structural Bases of Noncompetitive Inhibition of AMPA-Subtype Ionotropic Glutamate Receptors by Antiepileptic Drugs.
Neuron, 91, 2016
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6O9G
 | | Open state GluA2 in complex with STZ and blocked by AgTx-636, after micelle signal subtraction | | 分子名称: | CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2,Voltage-dependent calcium channel gamma-2 subunit, ... | | 著者 | Twomey, E.C, Yelshanskaya, M.V, Vassilevski, A.A, Sobolevsky, A.I. | | 登録日 | 2019-03-13 | | 公開日 | 2019-03-20 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | Mechanisms of Channel Block in Calcium-Permeable AMPA Receptors.
Neuron, 99, 2018
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5IWR
 | | Structure of Transient Receptor Potential (TRP) channel TRPV6 in the presence of barium | | 分子名称: | 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, BARIUM ION, Transient receptor potential cation channel subfamily V member 6 | | 著者 | Saotome, K, Singh, A.K, Yelshanskaya, M.V, Sobolevsky, A.I. | | 登録日 | 2016-03-22 | | 公開日 | 2016-06-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.85 Å) | | 主引用文献 | Crystal structure of the epithelial calcium channel TRPV6.
Nature, 534, 2016
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5IWT
 | | Structure of Transient Receptor Potential (TRP) channel TRPV6 in the presence of gadolinium | | 分子名称: | 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, GADOLINIUM ATOM, Transient receptor potential cation channel subfamily V member 6 | | 著者 | Saotome, K, Singh, A.K, Yelshanskaya, M.V, Sobolevsky, A.I. | | 登録日 | 2016-03-22 | | 公開日 | 2016-06-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Crystal structure of the epithelial calcium channel TRPV6.
Nature, 534, 2016
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5IWK
 | | Structure of Transient Receptor Potential (TRP) channel TRPV6 | | 分子名称: | 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, CALCIUM ION, Transient receptor potential cation channel subfamily V member 6 | | 著者 | Saotome, K, Singh, A.K, Yelshanskaya, M.V, Sobolevsky, A.I. | | 登録日 | 2016-03-22 | | 公開日 | 2016-06-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.247 Å) | | 主引用文献 | Crystal structure of the epithelial calcium channel TRPV6.
Nature, 534, 2016
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5IWP
 | | Structure of Transient Receptor Potential (TRP) channel TRPV6 in the presence of calcium | | 分子名称: | 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, CALCIUM ION, Transient receptor potential cation channel subfamily V member 6 | | 著者 | Saotome, K, Singh, A.K, Yelshanskaya, M.V, Sobolevsky, A.I. | | 登録日 | 2016-03-22 | | 公開日 | 2016-06-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.65 Å) | | 主引用文献 | Crystal structure of the epithelial calcium channel TRPV6.
Nature, 534, 2016
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5KBS
 | | Cryo-EM structure of GluA2-0xSTZ at 8.7 Angstrom resolution | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2,Voltage-dependent calcium channel gamma-2 subunit, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid | | 著者 | Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I. | | 登録日 | 2016-06-03 | | 公開日 | 2016-07-13 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (8.7 Å) | | 主引用文献 | Elucidation of AMPA receptor-stargazin complexes by cryo-electron microscopy.
Science, 353, 2016
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6DM0
 | | Open state GluA2 in complex with STZ and blocked by IEM-1460, after micelle signal subtraction | | 分子名称: | CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2,Voltage-dependent calcium channel gamma-2 subunit, ... | | 著者 | Twomey, E.C, Yelshanskaya, M.V, Vassilevski, A.A, Sobolevsky, A.I. | | 登録日 | 2018-06-04 | | 公開日 | 2018-08-22 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Mechanisms of Channel Block in Calcium-Permeable AMPA Receptors.
Neuron, 99, 2018
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6DM1
 | | Open state GluA2 in complex with STZ and blocked by NASPM, after micelle signal subtraction | | 分子名称: | CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2,Voltage-dependent calcium channel gamma-2 subunit, ... | | 著者 | Twomey, E.C, Yelshanskaya, M.V, Vassilevski, A.A, Sobolevsky, A.I. | | 登録日 | 2018-06-04 | | 公開日 | 2018-08-22 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Mechanisms of Channel Block in Calcium-Permeable AMPA Receptors.
Neuron, 99, 2018
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6DLZ
 | | Open state GluA2 in complex with STZ after micelle signal subtraction | | 分子名称: | CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2,Voltage-dependent calcium channel gamma-2 subunit | | 著者 | Twomey, E.C, Yelshanskaya, M.V, Vassilevski, A.A, Sobolevsky, A.I. | | 登録日 | 2018-06-04 | | 公開日 | 2018-08-22 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Mechanisms of Channel Block in Calcium-Permeable AMPA Receptors.
Neuron, 99, 2018
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6BO8
 | | Cryo-EM structure of human TRPV6 in nanodiscs | | 分子名称: | Transient receptor potential cation channel subfamily V member 6 | | 著者 | McGoldrick, L.L, Singh, A.K, Saotome, K, Yelshanskaya, M.V, Twomey, E.C, Grassucci, R.A, Sobolevsky, A.I. | | 登録日 | 2017-11-18 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Opening of the human epithelial calcium channel TRPV6.
Nature, 553, 2018
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