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7Y3C
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BU of 7y3c by Molmil
Crystal structure of TRIM7 bound to RACO-1
分子名称: E3 ubiquitin-protein ligase TRIM7,E3 ubiquitin-protein ligase TRIM7,TRIM7-RACO-1
著者Dong, C, Yan, X.
登録日2022-06-10
公開日2022-08-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献C-terminal glutamine acts as a C-degron targeted by E3 ubiquitin ligase TRIM7.
Proc.Natl.Acad.Sci.USA, 119, 2022
7Y3B
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BU of 7y3b by Molmil
Crystal structure of TRIM7 bound to GN1
分子名称: E3 ubiquitin-protein ligase TRIM7,TRIM7-GN1
著者Dong, C, Yan, X.
登録日2022-06-10
公開日2022-08-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献C-terminal glutamine acts as a C-degron targeted by E3 ubiquitin ligase TRIM7.
Proc.Natl.Acad.Sci.USA, 119, 2022
7Y3A
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BU of 7y3a by Molmil
Crystal structure of TRIM7 bound to 2C
分子名称: E3 ubiquitin-protein ligase TRIM7,E3 ubiquitin-protein ligase TRIM7,E3 ubiquitin-protein ligase TRIM7,TRIM7-2C
著者Dong, C, Yan, X.
登録日2022-06-10
公開日2022-08-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献C-terminal glutamine acts as a C-degron targeted by E3 ubiquitin ligase TRIM7.
Proc.Natl.Acad.Sci.USA, 119, 2022
7U5V
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BU of 7u5v by Molmil
Crystal structure of the Mixed Lineage Leukaemia (MLL1) SET Domain with the cofactor product S-Adenosylhomocysteine and Borealin peptide
分子名称: Borealin, Histone-lysine N-methyltransferase 2A, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者An, S, Cho, U.S, Oh, H, Sha, L, Xu, J, Kim, S, Yang, W, An, W, Dou, Y.
登録日2022-03-02
公開日2023-09-27
最終更新日2024-04-10
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Non-canonical MLL1 activity regulates centromeric phase separation and genome stability.
Nat.Cell Biol., 25, 2023
5WOE
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BU of 5woe by Molmil
Solution structure of the sorting nexin 25 phox-homology domain
分子名称: Sorting nexin-25
著者Chin, Y.K.Y, Mas, C, Mobli, M, Collins, B.M.
登録日2017-08-01
公開日2018-08-08
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Classification of the human phox homology (PX) domains based on their phosphoinositide binding specificities.
Nat Commun, 10, 2019
5Y0G
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BU of 5y0g by Molmil
Crystal structure of human FABP4 complexed with ligand 4-Fluoro-3-((4-methoxynaphthalene)-1-sulfonamido) benzoic acid
分子名称: 4-fluoranyl-3-[(4-methoxynaphthalen-1-yl)sulfonylamino]benzoic acid, Fatty acid-binding protein, adipocyte
著者Su, H.X, Liu, Q.F, Xu, Y.C.
登録日2017-07-17
公開日2018-06-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.542 Å)
主引用文献From hit to lead: Structure-based discovery of naphthalene-1-sulfonamide derivatives as potent and selective inhibitors of fatty acid binding protein 4
Eur J Med Chem, 154, 2018
5Y0X
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BU of 5y0x by Molmil
Crystal structure of human FABP4 complexed with ligand 2-fluoro-3-((4-methoxynaphthalene)-1-sulfonamido)benzoic acid
分子名称: 2-fluoranyl-3-[(4-methoxynaphthalen-1-yl)sulfonylamino]benzoic acid, Fatty acid-binding protein, adipocyte
著者Su, H.X, Liu, Q.F, Xu, Y.C.
登録日2017-07-19
公開日2018-06-06
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.604 Å)
主引用文献From hit to lead: Structure-based discovery of naphthalene-1-sulfonamide derivatives as potent and selective inhibitors of fatty acid binding protein 4
Eur J Med Chem, 154, 2018
5Y13
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BU of 5y13 by Molmil
Crystal structure of human FABP4 complexed with ligand 5-((4-bromonaphthalene)-1-sulfonamido)pentanoic acid
分子名称: 5-[(4-bromanylnaphthalen-1-yl)sulfonylamino]pentanoic acid, Fatty acid-binding protein, adipocyte
著者Su, H.X, Liu, Q.F, Xu, Y.C.
登録日2017-07-19
公開日2018-06-06
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献From hit to lead: Structure-based discovery of naphthalene-1-sulfonamide derivatives as potent and selective inhibitors of fatty acid binding protein 4
Eur J Med Chem, 154, 2018
5Y0F
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BU of 5y0f by Molmil
Crystal structure of human FABP4 complexed with ligand 2-fluoro-5-((4-methoxynaphthalene)-1-sulfonamido) benzoic acid
分子名称: 2-fluoranyl-5-[(4-methoxynaphthalen-1-yl)sulfonylamino]benzoic acid, Fatty acid-binding protein, adipocyte
著者Su, H.X, Liu, Q.F, Xu, Y.C.
登録日2017-07-17
公開日2018-06-06
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献From hit to lead: Structure-based discovery of naphthalene-1-sulfonamide derivatives as potent and selective inhibitors of fatty acid binding protein 4
Eur J Med Chem, 154, 2018
5Y12
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BU of 5y12 by Molmil
Crystal structure of human FABP4 complexed with ligand 5-((4-methoxynaphthalene)-1-sulfonamido)pentanoic acid
分子名称: 5-[(4-methoxynaphthalen-1-yl)sulfonylamino]pentanoic acid, Fatty acid-binding protein, adipocyte
著者Su, H.X, Liu, Q.F, Xu, Y.C.
登録日2017-07-19
公開日2018-06-06
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献From hit to lead: Structure-based discovery of naphthalene-1-sulfonamide derivatives as potent and selective inhibitors of fatty acid binding protein 4
Eur J Med Chem, 154, 2018
5ZNP
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BU of 5znp by Molmil
Crystal structure of PtSHL in complex with an H3K4me3 peptide
分子名称: 15-mer peptide from Histone H3.2, SHORT LIFE family protein, ZINC ION
著者Lv, X, Du, J.
登録日2018-04-10
公開日2018-07-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Dual recognition of H3K4me3 and H3K27me3 by a plant histone reader SHL.
Nat Commun, 9, 2018
5ZNR
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BU of 5znr by Molmil
Crystal structure of PtSHL in complex with an H3K27me3 peptide
分子名称: 17-mer peptide from Histone H3.2, SHORT LIFE family protein, SULFATE ION, ...
著者Lv, X, Du, J.
登録日2018-04-10
公開日2018-07-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.202 Å)
主引用文献Dual recognition of H3K4me3 and H3K27me3 by a plant histone reader SHL.
Nat Commun, 9, 2018
5ZWZ
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BU of 5zwz by Molmil
Crystal structure of Arabidopsis thaliana AGDP1 AGD34
分子名称: Agenet domain-containing protein
著者Du, X, Du, J.
登録日2018-05-17
公開日2018-11-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Arabidopsis AGDP1 links H3K9me2 to DNA methylation in heterochromatin
Nat Commun, 9, 2018
5ZWX
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BU of 5zwx by Molmil
Crystal structure of Raphanus sativus AGDP1 AGD12 in complex with an H3K9me2 peptide
分子名称: DUF724 domain-containing protein 6-like, H3(1-15)K9me2 peptide
著者Du, X, Du, J.
登録日2018-05-17
公開日2018-11-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Arabidopsis AGDP1 links H3K9me2 to DNA methylation in heterochromatin
Nat Commun, 9, 2018
7DQA
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BU of 7dqa by Molmil
Cryo-EM structure of SARS-CoV2 RBD-ACE2 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, CHLORIDE ION, ...
著者Wang, J, Lan, J, Wang, X.Q, Wang, H.W.
登録日2020-12-22
公開日2021-12-29
最終更新日2022-07-13
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Reduced graphene oxide membrane as supporting film for high-resolution cryo-EM
Biophys Rep, 7, 2022
7YHP
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BU of 7yhp by Molmil
CryoEM structure of Arabidopsis ROS1 in complex with 5mC-dsDNA at 3.1 Angstroms resolution
分子名称: DNA (40-MER), IRON/SULFUR CLUSTER, Sex-determining region Y protein,REPRESSOR OF SILENCING 1,DNA glycosylase/AP lyase ROS1
著者Du, X, Du, J.
登録日2022-07-14
公開日2022-11-30
最終更新日2023-03-08
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Molecular basis of the plant ROS1-mediated active DNA demethylation.
Nat.Plants, 9, 2023
7YHO
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BU of 7yho by Molmil
CryoEM structure of Arabidopsis ROS1 in complex with TG mismatch dsDNA at 3.3 Angstroms resolution
分子名称: DNA (40-MER), IRON/SULFUR CLUSTER, Sex-determining region Y protein,DNA glycosylase/AP lyase ROS1
著者Du, X, Du, J.
登録日2022-07-14
公開日2022-11-30
最終更新日2023-03-08
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Molecular basis of the plant ROS1-mediated active DNA demethylation.
Nat.Plants, 9, 2023
7YHQ
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BU of 7yhq by Molmil
CryoEM structure of Arabidopsis ROS1 in complex with a covalent-linked reaction intermediate at 3.9 Angstroms resolution
分子名称: DNA (40-MER), IRON/SULFUR CLUSTER, Sex-determining region Y protein,DNA glycosylase/AP lyase ROS1
著者Du, X, Du, J.
登録日2022-07-14
公開日2022-11-30
最終更新日2023-03-08
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Molecular basis of the plant ROS1-mediated active DNA demethylation.
Nat.Plants, 9, 2023
7YT9
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BU of 7yt9 by Molmil
crystal structure of AGD1-4 of Arabidopsis AGDP3
分子名称: AGD1-4 of Arabidopsis AGDP3
著者Zhou, X, Du, J.
登録日2022-08-13
公開日2022-10-12
最終更新日2023-01-11
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The H3K9me2-binding protein AGDP3 limits DNA methylation and transcriptional gene silencing in Arabidopsis.
J Integr Plant Biol, 64, 2022
7YTA
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BU of 7yta by Molmil
crystal structure of NtAGDP3 AGD1-2 in complex with an H3K9me2 peptide
分子名称: AGDP3 AGD1-2, H3(1-15)K9me2 peptide
著者Zhou, X, Du, J.
登録日2022-08-13
公開日2022-10-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献The H3K9me2-binding protein AGDP3 limits DNA methylation and transcriptional gene silencing in Arabidopsis.
J Integr Plant Biol, 64, 2022
7WHI
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BU of 7whi by Molmil
The state 2 complex structure of Omicron spike with Bn03 (2-up RBD, 4 nanobodies)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Bn03_nano1, Bn03_nano2, ...
著者Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L.
登録日2021-12-30
公開日2022-05-11
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody.
Cell, 185, 2022
7WHK
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BU of 7whk by Molmil
The state 3 complex structure of Omicron spike with Bn03 (2-up RBD, 5 nanobodies)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Bn03_nano1, Bn03_nano2, ...
著者Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L.
登録日2021-12-30
公開日2022-05-11
実験手法ELECTRON MICROSCOPY (3.01 Å)
主引用文献Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody.
Cell, 185, 2022
7WHJ
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BU of 7whj by Molmil
The state 1 complex structure of Omicron spike with Bn03 (1-up RBD, 3 nanobodies)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Bn03_nano1, Bn03_nano2, ...
著者Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L.
登録日2021-12-30
公開日2022-05-11
実験手法ELECTRON MICROSCOPY (3.27 Å)
主引用文献Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody.
Cell, 185, 2022
7X9E
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BU of 7x9e by Molmil
Crystal structure of the 76E1 Fab in complex with a SARS-CoV-2 spike peptide
分子名称: 76E1 Fab Heavy Chain, 76E1 Fab Light Chain, Spike peptide
著者Chen, X, Zhang, T, Ding, J, Sun, X, Sun, B.
登録日2022-03-15
公開日2022-05-11
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Neutralization mechanism of a human antibody with pan-coronavirus reactivity including SARS-CoV-2.
Nat Microbiol, 7, 2022
7U2X
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BU of 7u2x by Molmil
Cryo-EM structure of the pancreatic ATP-sensitive potassium channel in the presence of carbamazepine and ATP with Kir6.2-CTD in the down conformation
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Shyng, S.L, Sung, M.W, Driggers, C.M.
登録日2022-02-25
公開日2022-08-31
最終更新日2022-09-14
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K ATP Channel.
J.Mol.Biol., 434, 2022

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