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Engineered form of a putative cystathionine gamma-lyase
分子名称:	Cystathionine gamma-lyase, PYRIDOXAL-5'-PHOSPHATE, PYRUVIC ACID
著者	Chen, S, Wang, Y.
登録日	2019-05-10
公開日	2020-05-13
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (2.32 Å)
主引用文献	Structural characterization of cystathionine gamma-lyase smCSE enables aqueous metal quantum dot biosynthesis. Int.J.Biol.Macromol., 174, 2021

5D4K

Crystal structure of the human polymeric Ig receptor (pIgR) ectodomain
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Polymeric immunoglobulin receptor, SULFATE ION, ...
著者	Stadtmueller, B.M, Bjorkman, P.J.
登録日	2015-08-07
公開日	2016-03-16
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (2.599 Å)
主引用文献	The structure and dynamics of secretory component and its interactions with polymeric immunoglobulins. Elife, 5, 2016

6K1O

Apo form of a putative cystathionine gamma-lyase
分子名称:	Cystathionine gamma-lyase
著者	Chen, S, Wang, Y.
登録日	2019-05-10
公開日	2020-05-13
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (2.033 Å)
主引用文献	Structural characterization of cystathionine gamma-lyase smCSE enables aqueous metal quantum dot biosynthesis. Int.J.Biol.Macromol., 174, 2021

6K1L

E53A mutant of a putative cystathionine gamma-lyase
分子名称:	Cystathionine gamma-lyase, PYRIDOXAL-5'-PHOSPHATE, PYRUVIC ACID
著者	Chen, S, Wang, Y.
登録日	2019-05-10
公開日	2020-05-13
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (2.46 Å)
主引用文献	Structural characterization of cystathionine gamma-lyase smCSE enables aqueous metal quantum dot biosynthesis. Int.J.Biol.Macromol., 174, 2021

6K1N

PLP-bound form of a putative cystathionine gamma-lyase
分子名称:	Cystathionine gamma-lyase, PYRIDOXAL-5'-PHOSPHATE
著者	Chen, S, Wang, Y.
登録日	2019-05-10
公開日	2020-05-13
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (2.26 Å)
主引用文献	Structural characterization of cystathionine gamma-lyase smCSE enables aqueous metal quantum dot biosynthesis. Int.J.Biol.Macromol., 174, 2021

6O8I

BTK In Complex With Inhibitor
分子名称:	4-[(3S)-3-{[(2E)-but-2-enoyl]amino}piperidin-1-yl]-5-fluoro-2,3-dimethyl-1H-indole-7-carboxamide, Tyrosine-protein kinase BTK
著者	Pokross, M, Tebben, A.J, Watterson, S.H.
登録日	2019-03-11
公開日	2019-04-03
最終更新日	2019-04-24
実験手法	X-RAY DIFFRACTION (1.42 Å)
主引用文献	Discovery of Branebrutinib (BMS-986195): A Strategy for Identifying a Highly Potent and Selective Covalent Inhibitor Providing Rapid in Vivo Inactivation of Bruton's Tyrosine Kinase (BTK). J. Med. Chem., 62, 2019

5EFM

Beclin 1 Flexible-helical Domian (FHD) (141-171)
分子名称:	Beclin-1, SULFATE ION
著者	Sinha, S, Mei, Y.
登録日	2015-10-23
公開日	2016-07-20
最終更新日	2017-11-22
実験手法	X-RAY DIFFRACTION (1.95 Å)
主引用文献	Conformational Flexibility Enables the Function of a BECN1 Region Essential for Starvation-Mediated Autophagy. Biochemistry, 55, 2016

5EM9

Crystal structure of the SNX27 PDZ domain bound to the phosphorylated C-terminal 5HT4(a)R PDZ binding motif
分子名称:	SEP-LEU-GLU-SER-CYS-PHE, Sorting nexin-27
著者	Collins, B.M, Clairfeuille, T.
登録日	2015-11-06
公開日	2016-09-07
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (1.6 Å)
主引用文献	A molecular code for endosomal recycling of phosphorylated cargos by the SNX27-retromer complex. Nat.Struct.Mol.Biol., 23, 2016

5EMB

Crystal structure of the SNX27 PDZ domain bound to the C-terminal phosphorylated PTHR PDZ binding motif
分子名称:	GLU-GLU-TRP-SEP-THR-VAL-MET, Sorting nexin-27
著者	Collins, B.M, Clairfeuille, T.
登録日	2015-11-06
公開日	2016-09-07
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (0.85 Å)
主引用文献	A molecular code for endosomal recycling of phosphorylated cargos by the SNX27-retromer complex. Nat.Struct.Mol.Biol., 23, 2016

5EMA

Crystal structure of the SNX27 PDZ domain bound to the phosphorylated C-terminal LRRC3B PDZ binding motif
分子名称:	ASP-ASP-ILE-SEP-THR-VAL-VAL, GLYCEROL, Sorting nexin-27
著者	Collins, B.M, Clairfeuille, T.
登録日	2015-11-06
公開日	2016-09-07
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (1.32 Å)
主引用文献	A molecular code for endosomal recycling of phosphorylated cargos by the SNX27-retromer complex. Nat.Struct.Mol.Biol., 23, 2016

6KYQ

Crystal structure of DCLK1 Autoinhibited Kinase Domain
分子名称:	BETA-MERCAPTOETHANOL, Serine/threonine-protein kinase DCLK1
著者	Yu, Y, Chen, Q.
登録日	2019-09-20
公開日	2020-09-23
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (2.141 Å)
主引用文献	DCLK1 Autoinhibition and Activation in Tumorigenesis Innovation (N Y), 2021

6KYR

Crystal structure of DCLK1 mutant (P675L) Autoinhibited Kinase Domain
分子名称:	BETA-MERCAPTOETHANOL, Serine/threonine-protein kinase DCLK1
著者	Yu, Y, Chen, Q.
登録日	2019-09-20
公開日	2020-09-23
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (2.206 Å)
主引用文献	DCLK1 Autoinhibition and Activation in Tumorigenesis Innovation (N Y), 2021

5F1S

Crystal structure of the teleost fish polymeric Ig receptor (pIgR) ectodomain
分子名称:	polymeric Immunoglobulin Receptor
著者	Stadtmueller, B.M, Bjorkman, P.J.
登録日	2015-11-30
公開日	2016-03-16
最終更新日	2019-12-11
実験手法	X-RAY DIFFRACTION (1.749 Å)
主引用文献	The structure and dynamics of secretory component and its interactions with polymeric immunoglobulins. Elife, 5, 2016

5ELQ

Crystal structure of the SNX27 PDZ domain bound to the C-terminal DGKzeta PDZ binding motif
分子名称:	GLU-ASP-GLN-GLU-THR-ALA-VAL, Sorting nexin-27, TETRAETHYLENE GLYCOL
著者	Collins, B.M, Clairfeuille, T.
登録日	2015-11-05
公開日	2016-09-07
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (1.1 Å)
主引用文献	A molecular code for endosomal recycling of phosphorylated cargos by the SNX27-retromer complex. Nat.Struct.Mol.Biol., 23, 2016

6PZB

Cryo-EM structure of the pancreatic beta-cell SUR1 Apo state
分子名称:	ATP-binding cassette sub-family C member 8
著者	Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W.
登録日	2019-07-31
公開日	2019-08-14
最終更新日	2020-10-07
実験手法	ELECTRON MICROSCOPY (4.55 Å)
主引用文献	Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM. Elife, 8, 2019

5DAH

Crystal structure of PZP domain of human AF10 protein fused with Histone H3 peptide
分子名称:	Histone H3 peptide, Protein AF-10, SULFATE ION, ...
著者	Chen, S, Patel, D.J.
登録日	2015-08-19
公開日	2015-10-21
最終更新日	2024-03-06
実験手法	X-RAY DIFFRACTION (2.611 Å)
主引用文献	The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79. Mol.Cell, 60, 2015

5DAG

Crystal structure of PZP domain of human AF10 protein
分子名称:	Protein AF-10, ZINC ION
著者	Chen, S, Patel, D.J.
登録日	2015-08-19
公開日	2015-10-21
最終更新日	2024-03-06
実験手法	X-RAY DIFFRACTION (1.6 Å)
主引用文献	The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79. Mol.Cell, 60, 2015

6PZI

Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP only
分子名称:	ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8
著者	Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W.
登録日	2019-07-31
公開日	2019-08-14
最終更新日	2020-10-07
実験手法	ELECTRON MICROSCOPY (4.5 Å)
主引用文献	Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM. Elife, 8, 2019

6PZA

Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP and glibenclamide
分子名称:	5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ...
著者	Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W.
登録日	2019-07-31
公開日	2019-08-14
最終更新日	2020-10-07
実験手法	ELECTRON MICROSCOPY (3.74 Å)
主引用文献	Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM. Elife, 8, 2019

6PZ9

Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP and repaglinide
分子名称:	ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11, ...
著者	Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W.
登録日	2019-07-31
公開日	2019-08-14
最終更新日	2024-03-20
実験手法	ELECTRON MICROSCOPY (3.65 Å)
主引用文献	Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM. Elife, 8, 2019

7XHN

Structure of human inner kinetochore CCAN-DNA complex
分子名称:	CENP-W, Centromere protein C, Centromere protein H, ...
著者	Sun, L.F, Tian, T, Wang, C.L, Yang, Z.S, Zang, J.Y.
登録日	2022-04-09
公開日	2023-01-25
実験手法	ELECTRON MICROSCOPY (3.71 Å)
主引用文献	Structural insights into human CCAN complex assembled onto DNA. Cell Discov, 8, 2022

3CMI

Crystal structure of glutathione-dependent phospholipid peroxidase Hyr1 from the yeast Saccharomyces cerevisiae
分子名称:	Peroxiredoxin HYR1
著者	Zhang, W.J.Z, He, Y.X, Yu, J, Zhou, C.Z.
登録日	2008-03-21
公開日	2008-09-16
最終更新日	2023-11-01
実験手法	X-RAY DIFFRACTION (2.02 Å)
主引用文献	Crystal structure of glutathione-dependent phospholipid peroxidase Hyr1 from the yeast Saccharomyces cerevisiae Proteins, 73, 2008

4P7I

Crystal structure of the Merlin FERM/DCAF1 complex
分子名称:	GLYCEROL, Merlin, Protein VPRBP
著者	Wei, Z, Li, Y, Zhang, M.
登録日	2014-03-27
公開日	2014-04-09
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (2.6 Å)
主引用文献	Structural basis of the binding of Merlin FERM domain to the E3 ubiquitin ligase substrate adaptor DCAF1. J.Biol.Chem., 289, 2014

2O7N

CD11A (LFA1) I-domain complexed with 7A-[(4-cyanophenyl)methyl]-6-(3,5-dichlorophenyl)-5-oxo-2,3,5,7A-tetrahydro-1H-pyrrolo[1,2-A]pyrrole-7-carbonitrile
分子名称:	7A-[(4-cyanophenyl)methyl]-6-(3,5-dichlorophenyl)-5-oxo-2,3,5,7A-tetrahydro-1H-pyrrolo[1,2-A]pyrrole-7-carbonitrile, Integrin alpha-L
著者	Sheriff, S.
登録日	2006-12-11
公開日	2007-03-20
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (1.75 Å)
主引用文献	Design of LFA-1 antagonists based on a 2,3-dihydro-1H-pyrrolizin-5(7aH)-one scaffold. Bioorg.Med.Chem.Lett., 17, 2007

7XKE

Cryo-EM structure of DHEA-ADGRG2-FL-Gs complex
分子名称:	3-BETA-HYDROXY-5-ANDROSTEN-17-ONE, Adhesion G-protein coupled receptor G2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者	Guo, S.C, Xiao, P, Lin, H, Sun, J.P, Yu, X.
登録日	2022-04-19
公開日	2022-08-10
最終更新日	2023-03-15
実験手法	ELECTRON MICROSCOPY (2.9 Å)
主引用文献	Structures of the ADGRG2-G s complex in apo and ligand-bound forms. Nat.Chem.Biol., 18, 2022

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