5EMB

Crystal structure of the SNX27 PDZ domain bound to the C-terminal phosphorylated PTHR PDZ binding motif

Summary for 5EMB

Entry DOI	10.2210/pdb5emb/pdb
Related	4Z8J 5DLQ 5EM9 5EMA
Descriptor	Sorting nexin-27, GLU-GLU-TRP-SEP-THR-VAL-MET (3 entities in total)
Functional Keywords	endosome, pdz domain, sorting nexin, protein transport
Biological source	Rattus norvegicus (Rat) More
Cellular location	Early endosome membrane; Peripheral membrane protein: Q8K4V4
Total number of polymer chains	2
Total formula weight	11659.02
Authors	Collins, B.M.,Clairfeuille, T. (deposition date: 2015-11-06, release date: 2016-09-07, Last modification date: 2023-09-27)
Primary citation	Clairfeuille, T.,Mas, C.,Chan, A.S.,Yang, Z.,Tello-Lafoz, M.,Chandra, M.,Widagdo, J.,Kerr, M.C.,Paul, B.,Merida, I.,Teasdale, R.D.,Pavlos, N.J.,Anggono, V.,Collins, B.M. A molecular code for endosomal recycling of phosphorylated cargos by the SNX27-retromer complex. Nat.Struct.Mol.Biol., 23:921-932, 2016 Cited by PubMed: 27595347 DOI: 10.1038/nsmb.3290 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (0.85 Å)

Structure validation