6KYR

Crystal structure of DCLK1 mutant (P675L) Autoinhibited Kinase Domain

Summary for 6KYR

• Entry DOI: 10.2210/pdb6kyr/pdb
• Descriptor: Serine/threonine-protein kinase DCLK1, BETA-MERCAPTOETHANOL (3 entities in total)
• Functional Keywords: kinase, autoinhibition, signaling protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 73504.14

Authors

Yu, Y.,Chen, Q. (deposition date: 2019-09-20, release date: 2020-09-23, Last modification date: 2023-11-22)

• Primary citation: Cheng, L.,Yang, Z.,Guo, W.,Wu, C.,Liang, S.,Tong, A.,Cao, Z.,Thorne, R.F.,Yang, S.Y.,Yu, Y.,Chen, Q.; DCLK1 Autoinhibition and Activation in Tumorigenesis; Innovation (N Y), 2021; DOI: 10.1016/j.xinn.2021.100191

Experimental method

X-RAY DIFFRACTION (2.206 Å)