5HI3
| |
5HI5
| Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists | Descriptor: | (4S,20R)-7-chloro-N-methyl-4-{[(1-methyl-1H-pyrazol-5-yl)carbonyl]amino}-3,18-dioxo-2,19-diazatetracyclo[20.2.2.1~6,10~.1~11,15~]octacosa-1(24),6(28),7,9,11(27),12,14,22,25-nonaene-20-carboxamide, CAT-2000 FAB heavy chain, CAT-2000 light chain, ... | Authors: | Liu, S. | Deposit date: | 2016-01-11 | Release date: | 2016-08-31 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists. Sci Rep, 6, 2016
|
|
4Q8I
| Crystal Structure of beta-lactamase from M.tuberculosis covalently complexed with Tebipenem | Descriptor: | (4R,5S)-3-(1-(4,5-dihydrothiazol-2-yl)azetidin-3-ylthio)-5-((2S,3R)-3-hydroxy-1-oxobutan-2-yl)-4-methyl-4,5- dihydro-1H-pyrrole-2-carboxylic acid, Beta-lactamase, PHOSPHATE ION | Authors: | Hazra, S, Blanchard, J. | Deposit date: | 2014-04-27 | Release date: | 2014-08-20 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.901 Å) | Cite: | Tebipenem, a new carbapenem antibiotic, is a slow substrate that inhibits the beta-lactamase from Mycobacterium tuberculosis. Biochemistry, 53, 2014
|
|
4QB8
| |
2ZMV
| Crystal structure of Synbindin | Descriptor: | Trafficking protein particle complex subunit 4 | Authors: | Fan, F. | Deposit date: | 2008-04-21 | Release date: | 2008-07-01 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of human synbindin reveals two conformations of longin domain Biochem.Biophys.Res.Commun., 378, 2009
|
|
7W77
| cryo-EM structure of human NaV1.3/beta1/beta2-bulleyaconitineA | Descriptor: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Jiang, D, Li, X. | Deposit date: | 2021-12-03 | Release date: | 2022-04-06 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis for modulation of human Na V 1.3 by clinical drug and selective antagonist. Nat Commun, 13, 2022
|
|
7W7F
| Cryo-EM structure of human NaV1.3/beta1/beta2-ICA121431 | Descriptor: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2,2-diphenyl-~{N}-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]ethanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Jiang, D, Li, X. | Deposit date: | 2021-12-04 | Release date: | 2022-04-06 | Method: | ELECTRON MICROSCOPY (3.35 Å) | Cite: | Structural basis for modulation of human Na V 1.3 by clinical drug and selective antagonist. Nat Commun, 13, 2022
|
|
3BLI
| |
3BLE
| |
3BLF
| |
1RYQ
| Putative DNA-directed RNA polymerase, subunit e'' from Pyrococcus Furiosus Pfu-263306-001 | Descriptor: | DNA-directed RNA polymerase, subunit e'', ZINC ION | Authors: | Liu, Z.-J, Chen, L, Tempel, W, Shah, A, Arendall III, W.B, Rose, J.P, Brereton, P.S, Izumi, M, Jenney Jr, F.E, Lee, H.S, Poole II, F.L, Shah, C, Sugar, F.J, Adams, M.W.W, Richardson, D.C, Richardson, J.S, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG) | Deposit date: | 2003-12-22 | Release date: | 2004-08-10 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | Parameter-space screening: a powerful tool for high-throughput crystal structure determination. Acta Crystallogr.,Sect.D, 61, 2005
|
|
5F54
| Structure of RecJ complexed with dTMP | Descriptor: | MANGANESE (II) ION, Single-stranded-DNA-specific exonuclease, THYMIDINE-5'-PHOSPHATE | Authors: | Hua, Y, Zhao, Y, Cheng, K. | Deposit date: | 2015-12-04 | Release date: | 2016-06-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis for DNA 5 -end resection by RecJ Elife, 5, 2016
|
|
5F56
| Structure of RecJ complexed with DNA and SSB-ct | Descriptor: | ALA-ASP-LEU-PRO-PHE, DNA (5'-D(*CP*TP*GP*AP*TP*GP*GP*CP*A)-3'), MANGANESE (II) ION, ... | Authors: | Zhao, Y, Hua, Y, Cheng, K. | Deposit date: | 2015-12-04 | Release date: | 2016-06-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for DNA 5 -end resection by RecJ Elife, 5, 2016
|
|
5F55
| Structure of RecJ complexed with DNA | Descriptor: | DNA (5'-D(*GP*AP*TP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*C)-3'), MANGANESE (II) ION, SULFATE ION, ... | Authors: | Hua, Y, Zhao, Y, Cheng, K. | Deposit date: | 2015-12-04 | Release date: | 2016-06-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for DNA 5 -end resection by RecJ Elife, 5, 2016
|
|
3F6G
| Crystal structure of the regulatory domain of LiCMS in complexed with isoleucine - type II | Descriptor: | Alpha-isopropylmalate synthase, ISOLEUCINE, SULFATE ION, ... | Authors: | Zhang, P, Ma, J, Zhao, G, Ding, J. | Deposit date: | 2008-11-06 | Release date: | 2009-04-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular basis of the inhibitor selectivity and insights into the feedback inhibition mechanism of citramalate synthase from Leptospira interrogans Biochem.J., 421, 2009
|
|
5CH8
| Crystal structure of MDLA N225Q mutant form Penicillium cyclopium | Descriptor: | CHLORIDE ION, GLYCEROL, Mono- and diacylglycerol lipase, ... | Authors: | Xu, J, Xu, H, Hou, S, Liu, J. | Deposit date: | 2015-07-10 | Release date: | 2016-04-20 | Last modified: | 2017-09-27 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Lipase-Driven Epoxidation Is A Two-Stage Synergistic Process ChemistrySelect, 4, 2016
|
|
3F6H
| Crystal structure of the regulatory domain of LiCMS in complexed with isoleucine - type III | Descriptor: | Alpha-isopropylmalate synthase, ISOLEUCINE, ZINC ION | Authors: | Zhang, P, Ma, J, Zhao, G, Ding, J. | Deposit date: | 2008-11-06 | Release date: | 2009-04-21 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Molecular basis of the inhibitor selectivity and insights into the feedback inhibition mechanism of citramalate synthase from Leptospira interrogans Biochem.J., 421, 2009
|
|
8I6P
| The cryo-EM structure of OsCyc1 tetramer state | Descriptor: | Syn-copalyl diphosphate synthase, chloroplastic | Authors: | Ma, X.L, Xu, H.F, Tong, Y.R, Luo, Y.F, Dong, Q.H, Jiang, T. | Deposit date: | 2023-01-29 | Release date: | 2023-12-06 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural and functional investigations of syn-copalyl diphosphate synthase from Oryza sativa. Commun Chem, 6, 2023
|
|
8I6T
| The cryo-EM structure of OsCyc1 hexamer state | Descriptor: | Syn-copalyl diphosphate synthase, chloroplastic | Authors: | Ma, X.L, Xu, H.F, Tong, Y.R, Luo, Y.F, Dong, Q.H, Jiang, T. | Deposit date: | 2023-01-29 | Release date: | 2023-12-06 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural and functional investigations of syn-copalyl diphosphate synthase from Oryza sativa. Commun Chem, 6, 2023
|
|
8I6U
| The cryo-EM structure of OsCyc1 dimer state | Descriptor: | Syn-copalyl diphosphate synthase, chloroplastic | Authors: | Ma, X.L, Xu, H.F, Tong, Y.R, Luo, Y.F, Dong, Q.H, Jiang, T. | Deposit date: | 2023-01-29 | Release date: | 2023-12-06 | Method: | ELECTRON MICROSCOPY (7.9 Å) | Cite: | Structural and functional investigations of syn-copalyl diphosphate synthase from Oryza sativa. Commun Chem, 6, 2023
|
|
8IH5
| |
3GXA
| Crystal structure of GNA1946 | Descriptor: | METHIONINE, Outer membrane lipoprotein GNA1946, SULFATE ION | Authors: | Yang, X, Shen, Y. | Deposit date: | 2009-04-02 | Release date: | 2009-10-13 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Crystal structure of lipoprotein GNA1946 from Neisseria meningitidis J.Struct.Biol., 168, 2009
|
|
6AKW
| Crystal structure of RNA dioxygenase bound with an inhibitor | Descriptor: | 2-OXOGLUTARIC ACID, 2-[[2,6-bis(chloranyl)-4-(3,5-dimethyl-1,2-oxazol-4-yl)phenyl]amino]benzoic acid, Alpha-ketoglutarate-dependent dioxygenase FTO | Authors: | Yang, C.-G, Huang, Y, Gan, J. | Deposit date: | 2018-09-04 | Release date: | 2019-05-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia. Cancer Cell, 35, 2019
|
|
3IR1
| Crystal Structure of Lipoprotein GNA1946 from Neisseria meningitidis | Descriptor: | METHIONINE, Outer membrane lipoprotein GNA1946, SULFATE ION | Authors: | Yang, X, Wu, Z, Wang, X, Shen, Y. | Deposit date: | 2009-08-21 | Release date: | 2009-10-13 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal structure of lipoprotein GNA1946 from Neisseria meningitidis J.Struct.Biol., 168, 2009
|
|
3K3P
| |