2LAZ
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![BU of 2laz by Molmil](/molmil-images/mine/2laz) | Structure of the first WW domain of human Smurf1 in complex with a mono-phosphorylated human Smad1 derived peptide | Descriptor: | E3 ubiquitin-protein ligase SMURF1, Mothers against decapentaplegic homolog 1 | Authors: | Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J. | Deposit date: | 2011-03-22 | Release date: | 2011-07-06 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | A Smad action turnover switch operated by WW domain readers of a phosphoserine code. Genes Dev., 25, 2011
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2LAW
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![BU of 2law by Molmil](/molmil-images/mine/2law) | Structure of the second WW domain from human YAP in complex with a human Smad1 derived peptide | Descriptor: | Mothers against decapentaplegic homolog 1, Yorkie homolog | Authors: | Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J. | Deposit date: | 2011-03-22 | Release date: | 2011-07-06 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | A Smad action turnover switch operated by WW domain readers of a phosphoserine code. Genes Dev., 25, 2011
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2LAX
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![BU of 2lax by Molmil](/molmil-images/mine/2lax) | Structure of first WW domain of human YAP in complex with a human Smad1 doubly-phosphorilated derived peptide. | Descriptor: | Mothers against decapentaplegic homolog 1, Yorkie homolog | Authors: | Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J. | Deposit date: | 2011-03-22 | Release date: | 2011-07-06 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | A Smad action turnover switch operated by WW domain readers of a phosphoserine code. Genes Dev., 25, 2011
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2LB0
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![BU of 2lb0 by Molmil](/molmil-images/mine/2lb0) | Structure of the first WW domain of human Smurf1 in complex with a di-phosphorylated human Smad1 derived peptide | Descriptor: | E3 ubiquitin-protein ligase SMURF1, Mothers against decapentaplegic homolog 1 | Authors: | Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J. | Deposit date: | 2011-03-22 | Release date: | 2011-07-06 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | A Smad action turnover switch operated by WW domain readers of a phosphoserine code. Genes Dev., 25, 2011
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2LTV
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![BU of 2ltv by Molmil](/molmil-images/mine/2ltv) | YAP WW2 in complex with a Smad7 derived peptide | Descriptor: | Smad7 derived peptide, Yorkie homolog | Authors: | Macias, M.J, Aragon, E, Goerner, N, Xi, Q, Lopes, T, Gao, S, Massague, J. | Deposit date: | 2012-06-04 | Release date: | 2012-11-21 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-beta Pathways. Structure, 20, 2012
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2LB3
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![BU of 2lb3 by Molmil](/molmil-images/mine/2lb3) | Structure of the WW domain of PIN1 in complex with a human phosphorylated Smad3 derived peptide | Descriptor: | Mothers against decapentaplegic homolog 2, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Authors: | Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J. | Deposit date: | 2011-03-22 | Release date: | 2011-07-06 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | A Smad action turnover switch operated by WW domain readers of a phosphoserine code. Genes Dev., 25, 2011
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2LAY
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![BU of 2lay by Molmil](/molmil-images/mine/2lay) | Structure of the first WW domain of human YAP in complex with a phosphorylated human Smad1 derived peptide | Descriptor: | Mothers against decapentaplegic homolog 1, Yorkie homolog | Authors: | Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J. | Deposit date: | 2011-03-22 | Release date: | 2011-07-06 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | A Smad action turnover switch operated by WW domain readers of a phosphoserine code. Genes Dev., 25, 2011
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2LB2
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![BU of 2lb2 by Molmil](/molmil-images/mine/2lb2) | Structure of the second domain of human Nedd4L in complex with a phosphorylated pTPY motif derived from human Smad3 | Descriptor: | E3 ubiquitin-protein ligase NEDD4-like, Mothers against decapentaplegic homolog 3 | Authors: | Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J. | Deposit date: | 2011-03-22 | Release date: | 2011-07-06 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | A Smad action turnover switch operated by WW domain readers of a phosphoserine code. Genes Dev., 25, 2011
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2LB1
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![BU of 2lb1 by Molmil](/molmil-images/mine/2lb1) | Structure of the second domain of human Smurf1 in complex with a human Smad1 derived peptide | Descriptor: | E3 ubiquitin-protein ligase SMURF1, Mothers against decapentaplegic homolog 1 | Authors: | Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J. | Deposit date: | 2011-03-22 | Release date: | 2011-07-06 | Last modified: | 2016-04-27 | Method: | SOLUTION NMR | Cite: | A Smad action turnover switch operated by WW domain readers of a phosphoserine code. Genes Dev., 25, 2011
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2LAJ
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![BU of 2laj by Molmil](/molmil-images/mine/2laj) | Third WW domain of human Nedd4L in complex with doubly phosphorylated human smad3 derived peptide | Descriptor: | E3 ubiquitin-protein ligase NEDD4-like, Mothers against decapentaplegic homolog 3 | Authors: | Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J. | Deposit date: | 2011-03-16 | Release date: | 2011-07-06 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | A Smad action turnover switch operated by WW domain readers of a phosphoserine code. Genes Dev., 25, 2011
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2LTW
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![BU of 2ltw by Molmil](/molmil-images/mine/2ltw) | YAP WW1 in complex with a Smad7 derived peptide | Descriptor: | Smad7 derived peptide, Yorkie homolog | Authors: | Macias, M.J, Aragon, E, Goerner, N, Xi, Q, Lopes, T, Gao, S, Massague, J. | Deposit date: | 2012-06-04 | Release date: | 2012-11-21 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-beta Pathways. Structure, 20, 2012
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2LTY
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![BU of 2lty by Molmil](/molmil-images/mine/2lty) | NEDD4L WW2 domain in complex with a Smad7 derived peptide | Descriptor: | E3 ubiquitin-protein ligase NEDD4-like, Smad7 derived peptide | Authors: | Macias, M.J, Aragon, E, Goerner, N, Xi, Q, Lopes, T, Gao, S, Massague, J. | Deposit date: | 2012-06-04 | Release date: | 2012-11-21 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-beta Pathways. Structure, 20, 2012
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2LTX
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![BU of 2ltx by Molmil](/molmil-images/mine/2ltx) | Smurf1 WW2 domain in complex with a Smad7 derived peptide | Descriptor: | E3 ubiquitin-protein ligase SMURF1, Smad7 derived peptide | Authors: | Macias, M.J, Aragon, E, Goerner, N, Xi, Q, Lopes, T, Gao, S, Massague, J. | Deposit date: | 2012-06-04 | Release date: | 2012-11-21 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-beta Pathways. Structure, 20, 2012
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2LTZ
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![BU of 2ltz by Molmil](/molmil-images/mine/2ltz) | Smurf2 WW3 domain in complex with a Smad7 derived peptide | Descriptor: | E3 ubiquitin-protein ligase SMURF2, Smad7 derived peptide | Authors: | Macias, M.J, Aragon, E, Goerner, N, Xi, Q, Lopes, T, Gao, S, Massague, J. | Deposit date: | 2012-06-04 | Release date: | 2012-11-21 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-beta Pathways. Structure, 20, 2012
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3U5O
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![BU of 3u5o by Molmil](/molmil-images/mine/3u5o) | |
3U5M
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![BU of 3u5m by Molmil](/molmil-images/mine/3u5m) | |
3U5P
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![BU of 3u5p by Molmil](/molmil-images/mine/3u5p) | |
3U5N
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![BU of 3u5n by Molmil](/molmil-images/mine/3u5n) | |
5ODG
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![BU of 5odg by Molmil](/molmil-images/mine/5odg) | Crystal structure of Smad3-MH1 bound to the GGCT site. | Descriptor: | CHLORIDE ION, DNA (5'-D(P*CP*AP*GP*GP*CP*TP*AP*GP*CP*CP*TP*GP*CP*A)-3'), Mothers against decapentaplegic homolog 3, ... | Authors: | Kaczmarska, Z, Marquez, J.A, Macias, M.J. | Deposit date: | 2017-07-05 | Release date: | 2017-11-15 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors. Nat Commun, 8, 2017
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5OD6
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![BU of 5od6 by Molmil](/molmil-images/mine/5od6) | |
5MEY
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![BU of 5mey by Molmil](/molmil-images/mine/5mey) | Crystal structure of Smad4-MH1 bound to the GGCGC site. | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | Authors: | Kaczmarska, Z, Freier, R, Marquez, J.A, Macias, M.J. | Deposit date: | 2016-11-16 | Release date: | 2017-11-15 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors. Nat Commun, 8, 2017
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5NM9
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![BU of 5nm9 by Molmil](/molmil-images/mine/5nm9) | Crystal structure of the placozoa Trichoplax adhaerens Smad4-MH1 bound to the GGCGC site. | Descriptor: | DNA (5'-D(P*AP*TP*GP*CP*GP*GP*GP*CP*GP*CP*GP*CP*CP*CP*GP*CP*AP*T)-3'), Mothers against decapentaplegic homolog, ZINC ION | Authors: | Kaczmarska, Z, Freier, R, Marquez, J.A, Macias, M.J. | Deposit date: | 2017-04-05 | Release date: | 2017-11-15 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors. Nat Commun, 8, 2017
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5MF0
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![BU of 5mf0 by Molmil](/molmil-images/mine/5mf0) | Crystal structure of Smad4-MH1 bound to the GGCCG site. | Descriptor: | CHLORIDE ION, DNA (5'-D(P*AP*CP*GP*GP*GP*CP*CP*GP*CP*GP*GP*CP*CP*CP*GP*T)-3'), MH1 domain of human Smad4, ... | Authors: | Kaczmarska, Z, Freier, R, Marquez, J.A, Macias, M.J. | Deposit date: | 2016-11-16 | Release date: | 2017-11-15 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.03 Å) | Cite: | Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors. Nat Commun, 8, 2017
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5MEZ
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![BU of 5mez by Molmil](/molmil-images/mine/5mez) | Crystal structure of Smad4-MH1 bound to the GGCT site. | Descriptor: | CHLORIDE ION, DNA (5'-D(P*GP*CP*AP*GP*GP*CP*TP*AP*GP*CP*CP*TP*GP*CP*A)-3'), MH1 domain of human Smad4, ... | Authors: | Kaczmarska, Z, Freier, R, Marquez, J.A, Macias, M.J. | Deposit date: | 2016-11-16 | Release date: | 2017-11-15 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.98 Å) | Cite: | Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors. Nat Commun, 8, 2017
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7EBK
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![BU of 7ebk by Molmil](/molmil-images/mine/7ebk) | |