2LTX
Smurf1 WW2 domain in complex with a Smad7 derived peptide
Summary for 2LTX
Entry DOI | 10.2210/pdb2ltx/pdb |
Related | 2LTV 2LTW 2LTY 2LTZ |
NMR Information | BMRB: 18500 |
Descriptor | E3 ubiquitin-protein ligase SMURF1, Smad7 derived peptide (2 entities in total) |
Functional Keywords | ww, smurf1, smad7, protein binding-peptide complex, protein binding/peptide |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: Q9HCE7 Nucleus: O15105 |
Total number of polymer chains | 2 |
Total formula weight | 5836.44 |
Authors | Macias, M.J.,Aragon, E.,Goerner, N.,Xi, Q.,Lopes, T.,Gao, S.,Massague, J. (deposition date: 2012-06-04, release date: 2012-11-21, Last modification date: 2024-05-01) |
Primary citation | Aragon, E.,Goerner, N.,Xi, Q.,Gomes, T.,Gao, S.,Massague, J.,Macias, M.J. Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-beta Pathways. Structure, 20:1726-1736, 2012 Cited by PubMed: 22921829DOI: 10.1016/j.str.2012.07.014 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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